21st Joint Meeting of the British Endocrine Societies

Programme: Attended Posters

Mon 8 Apr | Tues 9 Apr | Wed 10 Apr | Thu 11 Apr | Attended Posters

Please note that even-numbered posters will be attended on Tuesday 9 April from 14.00 to 15.30 and odd-numbered posters will be attended on Wednesday 10 April from 13.30 to 15.00.

Bone
Clinical Cases
Cytokines and Growth Factors
Diabetes and Metabolism
Endocrine Tumours and Neoplasia
Genetics		 Growth and Development
Neuroendocrinology
Reproduction
Signalling
Steroids
Thyroid

Steroids

P243 Free cortisol index in suspected HPA axis pathology
LeRoux C, Dhillo W, Kong WM, Chapman G, Jones J & Alaghband Zadeh J
    
P244 Expression and corticosteroid regulation of serum and glucocorticoid regulated kinase, and epithelial sodium channel subunits in human ocular ciliary epithelium
Rauz S, Walker EA, Hughes SV, Coca-Prados M, Hewison M, Murray PI & Stewart PM
          
P245 Carbenoxolone, an inhibitor of 11b-hydroxysteroid dehydrogenase type 1, reduces intraocular pressure in patients with ocular hypertension
Cheung CMG, Rauz S, Murray PI & Stewart PM
     
P246 Comparison of the efficacy of long-term self-administration of subcutaneous human chorionic gonadotrophin with intramuscular exogenous testosterone (Sustanon) in male hypogonadism
Caddy SJ & Jones TH
     
P247 The prevalence and morbidity of long-term oral corticosteroid therapy
Mackie JH, Cooper MS & Stewart PM
               
P248 The relationship between smoking, statin therapy and testosterone in men with coronary artery disease
Morris PD, Pugh PJ, Hall J, Channer KS & Jones TH
      
P249 Androgens and diabetes mellitus in men with coronary artery disease
Morris PD, Pugh PJ, Roberts SA, Channer KS & Jones TH
  
P250 Testosterone and pro-inflammatory cytokines in men with chronic heart failure
Hall J, Pugh PJ, Jones RD, Corlett G, Channer KS & Jones TH
       
P251 Testosterone therapy improves depressive symptoms in men with chronic heart failure
Pugh PJ, Jones RD, Hall J, Channer KS & Jones TH
      
P252 Testosterone increases interleukin 10, an anti-inflammatory cytokine, in whole blood from hypogonadal men
Corlett GL, Pugh PJ, Kapoor D, Jones RD, Channer KS & Jones TH
      
P253 Testosterone and skeletal muscle parameters in men with chronic heart failure
Pugh PJ, Jones RD, Hall J, Channer KS, Jones TH & van Beek E
      
P254 Hypoglycaemia and Addison’s disease - cause or association?
Kennedy A, Hadden DR & Hunter SJ
      
P255 Intermittent hyponatraemia due to isolated ACTH deficiency
Ajjan R, Scott E, Ismail A, Walker P & Nagi DK
     
P256 Expression of adipose 11b-hydroxysteroid dehydrogenase type 1 in human obesity
Tomlinson JW, Sinha B, Hewison M & Stewart PM
      
P257 Enhanced hepatic A-ring reduction of glucocorticoids in obesity: regulation by glucocorticoids and insulin
Livingstone DEW, McInnes KJ, Walker BR & Andrew R
        
P258 In vitro expression of catalytically active human aldosterone synthase
Inglis GC, Davies E, Stewart PM, Fraser R & Connell JMC
      
P259 Reduced glucocorticoid receptor expression in obese Zucker rats: protection from the metabolic consequences of obesity?
Drake AJ, Cleasby ME, Livingstone DEW, Seckl JR & Walker BR
    
P260 Assessment of mineralocorticoid status by urinary corticosteroid profiling using gas chromatography-mass spectrometry (GCMS)
Shakerdi L, Fraser R & Wallace AM
        
P261 Angiotensin II and ACTH differentially regulate adrenal steroid production through key steroidogenic enzymes
Kelly SN, Smith TP, Cunningham SK, Young LS & McKenna TJ
       
P262 A role for nur-77 in the regulation of adrenal steroid production
Kelly SN, Smith TP, Cunningham SK, McKenna TJ & Young LS
         
P263 Growth hormone increases fat mass in patients with simple obesity
Tomlinson JW, Crabtree N, Clark PMS, Holder G, Shackleton CHL & Stewart PM
         
P264 Cortisone reductase (11b-hydroxysteroid dehydrogenase type 1) deficiency presenting with features of late onset congenital adrenal hyperplasia
Laing I, Adams JE, Wood PJ, Taylor NF & Ray DW
     
P265 Phytoestrogen dietary supplementation does not alter serum IGF-1 levels in postmenopausal women
Jayagopal V, Albertazzi P, Kilpatrick ES, Jennings PE & Atkin SL
      
P266 Testosterone exhibits a calcium antagonistic action upon store operated calcium channels in cultured vascular smooth muscle cells
Jones RD, Ruban LN, Pugh PJ, English KM, Channer KS & Jones TH
         
P267 Testosterone does not increase the production of cyclic AMP (cAMP) in cultured vascular smooth muscle cells
Ruban LN, Jones RD, Pugh PJ, English KM, Channer KS & Jones TH
        
P268 Circulating steroid levels in the testicular feminised (Tfm) mouse
Jones RD, Hall J, Pugh PJ, English KM, Channer KS & Jones TH
      
P269 Size at birth, gestational age and cortisol secretion in adult life: do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?
Kajantie E, Phillips DIW, Dunkel L, Andersson S, Barker DJP, Forsen T, Osmond C, Wood PJ, Tuominen J & Eriksson J
        
P270 Roles of k-ras and Gadd153 in 17b-oestradiol-induced apoptosis in colo205 cells
Qiu Y, Langman MJS & Eggo MC
       
P271 Fetal and maternal regulation of aldosterone synthase and 11b-hydroxylase
Lo YC, Mason JI, Williams BC, Lloyd-MacGilp SA & Kenyon CJ
      
P272 Quantification of aldosterone synthase (CYP11B2) gene expression in the adrenal gland and central nervous system following dietary sodium manipulation
Ye P, Kenyon CJ, Mackenzie SM, Fraser R, Connell JMC & Davies E
       
P273 Long-term overall success after transsphenoidal surgery for Cushing’s disease: time for a reappraisal of therapy?
Kennedy A, Wiggam MI, Hadden DR, McCance DR, Sheridan B & Atkinson AB
      
P274 What value do cortisol measurements provide in monitoring metyrapone therapy?
Wieringa G, Naing S, Perry LA, Anderson JM, Wiener K, Burrows GC, Warburton R, Kane JW & Trainer PJ
     

Thyroid
P275 Atrial fibrillation predicts mortality in thyrotoxicosis
Osman F, Daykin J, Sheppard MC, Gammage MD & Franklyn JA
       
P276 Increased force/unit cross sectional area as well as increased bulk causes recovery in proximal strength in hyper/hypothyroidism
Khaleeli AA & Houghton T
      
P277 Influence of pre-treatment factors on outcomes following the use of high fixed dose radioiodine treatment for hyperthyroidism
Barton DM, Buch HN, Baskar V, Kumar H & West TET
       
P278 The female preponderance to autoimmune thyroid disease is reduced in multiplex type 1 diabetes families
Tait KF, Berman J, Carr-Smith J, Rowe B, Heward JM, Franklyn JA, Todd JA, Bain SC, Barnett AH & Gough SCL
      
P279 Analysis of a clinical workstation thyrotoxicosis share-care scheme
Chatterjee S, Kieffer V & Howlett TA
       
P280 Thyrotoxic heart failure in a previously fit 40 year old woman
Banerjee M, Javaid K, Khan S & Vice PA
      
P281 Delayed resolution of endothelial dysfunction despite biochemical correction of thyrotoxicosis
Obuobie K, Evans SA & Lazarus JH
P282 Thyroid function in paediatric patients with malignancy after radiotherapy in Isfahan, Iran
Hashemipoor M, Golpaiegani F, Babazadeh S, Maafi AR, Javanmardy GA & Iranpour R
      
P283 Thyroid hormone (TH) regulation of iodothyronine deiodinase and thyroid hormone receptor (TR) expression in placental trophoblast cells
Hobbs EL, Driver P, McCabe CJ, Franklyn JA & Kilby MD
      
P284 Pituitary tumor transforming gene and basic fibroblast growth factor-2 - novel potential molecular indicators for thyroid cancer
Boelaert K, McCabe CJ, Tannahill LA, Gittoes NJL, Eggo MC, Watkinson JC, Sheppard MC & Franklyn JA
      
P285 Outcome at two years of fixed dose radioiodine treatment for thyrotoxicosis
Forde I, Corgie D & Trainer PJ
       
P286 Effect of blood exchange transfusion on neonatal thyroid function
Iranpour R, Hashemipoor M, Haghshenas I, Hamidi M & Heydarzadeh A
       
P287 Provision of a new strength thyroxine tablet would facilitate tight control of TSH concentrations in primary hypothyroidism
Bhala N, Weetman AP & Jenkins RC
      
P288 The follow-up status of patients 10 years after treatment with radioactive iodine (RI) for hyperthyroidism
Varghese B & Trainer PJ
   
P289 A cluster of cases of subacute thyroiditis in north east England
Craig FE, Frewin S & Perros P
      
P290 Audit of the management of maternal hypothyroidism in pregnancy: implications for service provision
Hannon T, Sturgiss S & Ball SG
        
P291 Lithium associated thyrotoxicosis
Ghosh S & Bangar V
        
P292 Thyroid dysfunction in diabetes: can we justify routine screening?
Moulik PK, Nethaji C & Khaleeli AA
      
P293 Clinical assessment of two methods for measuring thyrotropin binding inhibiting immunoglobulin (TBII)
Schardt CW, Perros P, Fleetwood A, Self C & Weightman DR
P294 Thyroid peroxidase antibodies are not a surrogate for thyroid stimulating antibodies in the investigation of the etiology of thyrotoxicosis
Evans C, Alkhafaji F, Selwood C & Ludgate M
       
P295 Molecular characterisation of congenital hypothyroidism
Jordan NJ, Gregory J, Evans C, Williams NM, Owen MJ & Ludgate Mv
     
P296 Pyrimidine and purine metabolism in human leukocytes in autoimmunological thyroid diseases - RNA expression of some enzymes
Lewinski A, Brzezianska E, Karbownik M, Zasada K, Migdalska-Sek M & Pastuszak-Lewandoska D
      
P297 Protein kinase C delta interacts with the sodium iodide symporter (NIS) to increase its activity in human thyrocytes
Turner FE & Eggo MC
       
P298 Profile of the thyroid function in a population with type-2 diabetes mellitus
Nobre EL, Jorge Z, Pratas S, Silva C & Castro JJ
         
P299 Thyroid function in early pregnancy. A prospective study
Bohnet HG & Martens K
      
P300 Determining the molecular causes of hyperthyroidism
Al-Khafaji F, Baker G & Ludgate M
        
P301 Telephone follow-up following radioiodine therapy for thyrotoxicosis improves outcome
Murphy E, Mehta S, Gannon D, Bassett JHD, Frank J & Meeran K
       
P302 Environmental factors produce variation within a model of thyroid eye disease
Baker GRC & Ludgate M
        
P303 The use of lithium as an adjunct to radioiodine therapy for thyrotoxicosis
Murphy E, Bassett JHD, Frank J & Meeran K
       
P304 Adenoviral expression of secreted Tie-2 reduces thyroid follicular cell growth and adhesion
Ramsden JD, Mautner V, Watkinson J & Eggo MC
       
P305 Primary hypothyroidism and unilateral thyroid eye disease: a case report
Ozgen AG, Terzioglu E, Duman E & Kabalak T
    
P306 Plasma total and free tissue factor pathway inhibitor, tissue plasminogen activator antigen, and plasminogen activator inhibitor antigen levels in various thyroid disorders
Comlekci A, Ozcan MA, Demirkan F, Sari I, Demir T, Ozsan H, Oruk G & Yesil S
       
P307 High thyroglobulin autoantibodies in Sri Lankan Tamil tea workers exhibit an epitope-recognition pattern distinct from healthy subjects and autoimmune thyroid disease (AITD) patients
Okosieme OE, Parkes AB, Premawardhana LDKE, Ruf J, Carayon P & Lazarus JH
     
P308 Thyroid disease in patients with genetic haemochromatosis - a prospective study
Murphy MS & Walsh CH
ics		  

Bone

P1 Bone mineral density in children with insulin dependent diabetes mellitus (IDDM)
Triantafyllidis G, Ouzouni G, Bizanias S, Karakaidos D, Karahaliou E, Zosi P & Karis C
   
P2 Bone mineral density of asthmatic children after long term treatment with inhaled corticosteroids
Ouzouni G, Bizanias S, Karakaidos D, Vovolis V, Triantafyllidis G, Nikolaidou A & Karis C
    
P3 Investigation into the plasticity of adult human bone marrow adipocytes
Ioannidou S, Staley W, Byers RJ, Selby PL, Freemont AJ & Hoyland JA
       
P4 Is bone mineral density in women with type 2 diabetes different from nondiabetic women?
Pajouhi M, Larijani B, Soltani A, Hossieni R, Baradar-Jalili R & Adibi H
   
P5 Changes in parathyroid hormone sensitivity and rhythmicity and its effects on bone metabolism following growth hormone replacement in adult growth hormone deficient patients
Ahmad AM, White HD, Thomas J, Clewes A, Hopkins MT, Guzder R, Ibrahim H, Durham BH, Vora JP & Fraser WD
       
P6 Evaluation of vitamin D deficiency and other bone biochemical factors in the urban population of Tehran-winter 2001
Larijani B, Soltani A, Pajouhi M, Hashemipoor S, Khalili-fard AR, Hamidi Z & Adibi H
         
P7 Bone turnover markers after a single intravenous injection of growth hormone in adults with growth hormone deficiency
Al-Mrayat M, Kyd P, Donaldson O & Johnston DG
          
P8 Availability of a reliable marker of bone resorption in serum, C-terminal cross-linking telopeptide of type I collagen, for evaluation of metabolic bone disease
Fitzgibbon MC, Murray BF, McBrinn YM, O’Shea D, McKenna MJ & McKenna TJ
      
P9 Development of bone remodelling balance and turnover indices in patients with metabolic bone disease
Murray BF, Fitzgibbon MC, McBrinn YM, O’Shea D, McKenna MJ & McKenna TJ
        
P10 A comparative study of raloxifen and estrogen on bone strength and cholesterol levels in ovariectomized rats
Oge A, Bayraktar F, Sevin G, Uyulgan B, Yilmaz C & Kabalak T
         
P11 Effect of rosiglitazone on bone strength in osteoporotic rats
Oge A, Bayraktar F, Uyulgan B, Yilmaz C & Kabalak T
           

Clinical Case Reports
P12 The perils of low dose locally delivered steroids
Browne DL, Cummings MH, Murdoch SR, Cook LJ & Meeking DR
     
P13 Isolated growth hormone deficiency and BPES
Varghese B, Donnai D & Shalet SM
        
P14 Pituitary mass and hypopituitarism with Wegeners granulomatosis
   Freeman MS & Belchetz PE
          
P15 Hyperparathyroidism and polycythaemia
Kamalakannan D, Baskar V, Buch HN, Barton DM & Singh BM
       
P16 Type 1 diabetes in the elderly
Kumar J, Laji K & Page M
       
P17 Management of thyrotoxicosis in a non-compliant pregnant woman
John LJ & Lloyd JL
          
P18 Lack of cortisol response using the glucagon stimulation test in diabetic autonomic neuropathy
Devendra D, Millward BA & Flanagan DEH
        
P19 ‘Brittle Addison’s disease’ but not ‘Brittle diabetes’ in a young woman with Addison’s disease and type 1 diabetes mellitus
Beshyah SA, Aylwin S, Abouglila K & Monson JP
        
P20 A rare cause of intrasellar mass: cholesterol granuloma
Kelestimur F, Unluhizarci K, Colak R, Balkanli S, Karahan IO, Selcuklu A, Ozturk F & Bayram F
     
P21 Mitochondrial inheritance of maternal, familial short stature with diabetes mellitus
Sabin MA, Crowne EC, Poulton J & Shield JPH
  
P22 Prolactin elevation to 16,630 mU/l in a case of a large non-functioning pituitary adenoma
Syed AA, Mathias DB, Wahid ST, Hall K & Weaver JU
  
P23 Glucocorticoid remediable aldosteronism. A Northern Ireland experience
McLaughlin D, Harper R, Inglis GC, Connell JMC, Sheridan B & Atkinson AB
      
P24 Acute polyarticular synovitis complicating Graves’ disease
Wong SPY, Malik IA, Huda B, Dewan S & McCrimmon RJ
      
P25 Congenital adrenal hyperplasia: a tale of two enzymes
Chaudhri O, Goodlad C, Hameed A, Barakat M & Meeran K
         
P26 A new management for congenital adrenal hyperplasia?
Goodlad C, Chaudhri O, Barakat MT & Meeran K
       
P27 A case of pseudohypoparathyroidism with diagnostic dilemmas
Kennedy A, Hadden DR & Hunter SJ
            
P28 Cushing’s syndrome of indeterminate origin. Successful treatment of a liver abscess after therapy with a block and replacement medical regimen
Harding JA, Kennedy A, Sheridan B & Atkinson AB
         
P29 Self-hypophysectomy - and return to normal
Stewart AL, Connolly V & Kelly WF
          
P30 Acute presentation of a ruptured craniopharyngioma
Lane H, Ray A, Vafidis J & Davies JS
         
P31 What is the natural history of scalp hairloss in association with the use of somatostatin analogues in the treatment of acromegaly?
Bradley KJ, Turner HE, Wass JAH & Colao A
        
P32 Fish oil and antacids: a cautionary tale
Hameed A, Fielding R, Barakat MT, Pusey CD & Williams GR
       
P33 Primary hyperaldosteronism in association with primary hyperparathyroidism and prolactinoma - a case report
Marshall JA & Kong MF
           
P34 A case of Gitelman’s syndrome
Gilbert J & Price P
       
P35 Iatrogenic acromegaly
Tuthill A, McKenna TJ & O’Shea D
       
P36 Efficacy and safety of high dose testosterone therapy in partial androgen insensitivity
Bandyopadhyay S, Watson WA, Park CM, Abraham P, Philip S, Acharya S & Bevan JS
        
P37 Xanthoma Disseminatum: a rare cause of hypopituitarism
Ray S & Belchetz PE
        
P38 Sustained improvement in vision in a recurrent growth hormone secreting macroadenoma during treatment with octreotide in the absence of marked tumour shrinkage. A reason for cautious optimism?
Harding JA, Sheridan B & Atkinson AB
       
P39 Hyperprolactinaemia in a patient taking the herbal remedy Agnus Castus
Harding JA, Sheridan B & Atkinson AB
         
P40 Differentiated thyroid carcinoma with large bony metastases - what is the best approach?
Watson WA, Park CM, Abraham P, Bandyopadhyay S, Philip S, Acharya SH, Samuel L & Bevan JS
        
P41 An unusual presentation of sarcoidosis
King P & Kong MF
         
P42 A spontaneously resolving mediastinal parathyroid adenoma with no previous Tc-99m pertechnetate uptake
Idris IR, Kong MF & King P
          
P43 A patient with Turner’s syndrome, type 2 diabetes and primary biliary cirrhosis
Ray S, Gilbey SG & Mansfield MW
              
P44 A case of polyuria, thirst and weight loss
Nethaji C, Moulik PK & Khaleeli AA
           
P45 Growth hormone deficiency in salt-losing congenital adrenal hyperplasia
Traggiai C, Conway GS & Stanhope R
       
P46 Steroid responsiveness in a case of Riedel’s thyroiditis and retroperitoneal fibrosis
Khaleeli AA, Al-Jafari MS & Moulik PK
           
P47 Thromboembolism in patients with Cushing’s disease - a retrospective case review
Ahmad B, Turner HE & Wass JAH
       
P48 Multidisciplinary management of Cushing’s syndrome due to a malignant thymic carcinoid tumour
Park CM, Watson WA, Abraham P, Acharya SH, Bandyopadhyay S, Philip S, Samuel L, Nicolson M & Bevan JS
            
P49 Li-Fraumeni syndrome with adrenocortical tumours producing oestrogens in the father and testosterone in his 18 month old daughter
O’Connell J, Green A, O’Shea D & McKenna TJ
         
P50 Cushing’s disease and nasal obstruction from a large biochemically ‘silent’ corticotroph adenoma
Gable DR, Powell M, Pollock J & Ahlquist JA
         
P51 Cushing’s syndrome presenting with weight loss and type II diabetes mellitus
Coll A, Jerges WK, Taylor NF, Wood PJ, Scott-Coombes DM, McGregor AM & Aylwin SJB
        
P52 Extremely long effects of vitamin D therapy: a near-fatal complication of thyroid surgery
Gable DR & Ahlquist JA
       
P53 Severe thyroid eye disease associated with stable primary hypothyroidism
Prakash PK, Biswas M, Brown A, Raghuram A & Hanna FWF
       
P54 Apparent mineralocorticoid excess caused by Barnips cough tablets
Lewandowski KC & Burr WA
      
P55 Bilateral adrenal histoplasmosis
Rohrer JD, Hamour SMA, Tan TMM & Bouloux PMG
        
P56 Cranial diabetes insipidus and possible prolactinoma - an interesting case
Razvi S & McCulloch AJ
         
P57 The use of the domperidone test in differentiating macroprolactinaemia from true hyperprolactinaemia
Pinto L, Evans M, Hanna F & Scanlon M
        
P58 A case report of hungry bone syndrome in the course of Graves’ disease
Boysan SN, Kadioglu P, Tiryakioglu O, Acbay O & Gundogdu S
        
P59 Anaplastic carcinoma of the thyroid presenting with hyperthyroidism
Dale JE, Watkinson J, Sheppard MC & Franklyn JA
          
P60 A case of Addison’s disease caused by the antiphospholipid syndrome
Leonard N, Weir C, Boyd K & Ritchie C
          
P61 Acute adrenal insufficiency and encephalomeningitis with cerebral haemorrhage: a case of secondary lupus anticoagulant syndrome?
Hamour SMA, Tan TMM, Rohrer JD, Leff A, Brenner R & Bouloux PMG
         
P62 Pituitary carcinoma - a pain in the head and a pain in the neck
Ayuk J & Gittoes NJL
         
P63 A case of false immunoassay results due to assay interference
Park AJ, Goodlad C, Chaudhri O, Donaldson M, Ghatei M & Meeran K
        
P64 Prolactinoma and macroprolactin
Fayers K, Cox S, Bower L, Dyer RG, Dearman G & Fahie-Wilson MN
          
P65 Is the endocrine nurse too accessible?
Stewart SE & McGregor E
              
P66 Ghanaian influenza
Field BCT, Davis K & Meeran K
           
P67 Seizures as first manifestation of catch 22 syndrome in adulthood
Nath U, Jones RE & Chapman AJ
         
P68 An androgen-secreting tumour presenting with resistant hypertension and an ‘incidentaloma’
Kong MF, Moleele G & King P
        
P69 A near fatal case of haematuria
Kumar H, O’Shea L, Joyce M, Tanner A & Barragry J
      
P70 An unusual case of secondary amenorrhea
O’Shea L, Callally E, Leen E, Barry-Kinsella C & Screenan S
      
P71 A diagnostic trilemma of primary adrenal failure, sepsis and HITTS
O’Shea LA, O’Gorman O, Regan F, Enright H & Barragry JM
          

Cytokines and Growth Factors

P72 Studying of e-selectin in patients with diabetes type 1 and microangiopathy
Dedov I, Shestakova M, Kochemasova T, Osipova T & Baryshnikov A
          
P73 The universal expression of ghrelin in normal and malignant breast tissue and its association with tumourigenic genes
Laban C, Ogunkolade W, Bustin S, Carpenter R & Jenkins PJ
    
P74 Antiangiogenic effect of lanreotide on GH-secreting pituitary adenomas
Garcia de la Torre N, Fazal-Sanderson V, Wass JAH & Turner HE
     
P75 Ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon: importance of P-selectin, CXC chemokines
Riaz AA, Wan MX, Dawson PM, Jeppsson B & Thorlacius H
       
P76 Expression of the membrane interleukin-6 receptor (mIL6R) but absence of shedding of soluble IL6R (sIL6R) in human pituitary tumour cells
Borg SA, Kerry KE, Hall J, Suliman ME, Royds JA & Jones TH
           
P77 Inhibitory effects of interleukin-1a, interleukin-6 and leptin on growth of HP75 human pituitary tumour cells
Hall J, Borg SA, Kerry KE & Jones TH
         
P78 Leptin increases expression of CD11b on human neutrophils
Zarkesh-Esfahani SH, Pockley G, Norman K, Metcalfe RA, Aylott C, Hellewell P, Weetman AP & Ross RJM
        
P79 Adrenomedullin stimulation of cytokines and growth factor release in endothelial cells and skin fibroblasts: a possible role in wound healing
Renshaw D, Hinson JP & Kapas S
        
P80 Growth hormone treatment does not decrease homocysteine levels
Lewandowski KC, Murray RD, Drzewoski J, Czupryniak L, Hillhouse EW, Shalet SM & Randeva HS
        
P81 Bacterial lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells
Vakharia K, Renshaw D & Hinson JP
             
P82 IGFBP-5 regulates IGF-I mediated signaling and survival in the mouse mammary gland
Marshman E, Streuli CH, Green KA, White A & Westwood M
         

Diabetes and Metabolism
 

P83 Effects of growth hormone replacement (GHR) on VLDL and LDL APOB100 kinetics in growth hormone deficient (GHD) subjects
Kearney TM, Navas de Gallegos C, Miras A, Parker K, Anayaouku V, Gray R, Venkatesan S & Johnston DG
     
P84 The effect of growth hormone replacement (GHR) on lipoprotein composition in growth hormone deficient (GHD) hypopituitary adults
Kearney TM, Proudler A, Navas de Gallegos C, Robinson S, Venkatesan S & Johnston DG
         
P85 Demonstration of diurnal variation of plasma glycated insulin in type 2 diabetes
Lindsay JR, McKillop AM, Mooney MH, O’Harte FP, Bell PM & Flatt PR
      
P86 Increased red cell folate subsequent to folic acid supplementation in type II diabetes results in a reduction in microalbumin excretion but an increased atherogenic lipid profile
Child DF, Hudson PR, Jones H, Davies GK, De P, Harvey JN & Williams CP
          
P87 Changes in anthropometric, metabolic and insulin resistance indices among offspring of Caribbean patients with type 2 diabetes mellitus
Ezenwaka CE, Kalloo R, Kuhn-Velten WN & Eckel J
          
P88 Insulin secretion and metabolic control in Caribbean type 2 diabetic patients commonly treated with sulphonylurea drugs
Ezenwaka CE, Offiah NV & Kalloo R
      
P89 Abnormalities of vascular function and fibrinolysis in young women with polycystic ovary syndrome
Kelly CJG, Sattar N, Petrie JR, Lyall H & Connell JMC
         
P90 Insulin resistance and metabolic syndrome in obese children
Averianov AP, Bolotova NV & Lazebnikova SV
     
P91 Thioland and steroid levels in polycystic ovary syndrome
Dvorakova K, Tallova J, Hill M & Vrbikova J
        
P92 Acanthosis nigricans: a valid clinical marker of insulin resistance in obesity
Packianathan I, Stevenson O & Finer N
        
P93 Effects of ACE inhibitors on myocardial infarction, cerebrovascular death, stroke, diabetic nephropathy and insulin sensitivity in patients with diabetes mellitus type 2
Velija-Asimi Z
       
P94 Screening strategy and cost analysis of gestational diabetes mellitus in Iranian pregnant women
Larijani B, Hosseinnezhad A, Bastanhagh MH & Pajouhi M
         
P95 Incidence of hypertension in patients with gestational diabetes mellitus and non-diabetic pregnant women
Hosseinnezhad A, Larijani B, Pajouhi M & Bastanhagh MH
         
P96 Effectiveness of a weight management programme in a hospital staff setting
O’ Connell J, Robinson D, McLaughlin A, Stuart B, Orsmond E & O’Shea D
          
P97 The expression of resistin mRNA in human adipose tissue
McTernan PG, McTernan CL, Lauer MA, Barnett AH & Kumar S
      
P98 Expression of adiponectin mRNA in human adipose tissue depots in non-diabetic and diabetic patients
Fisher FFM, McTernan PG, McTernan CL, Chetty R, Anwar AJ, Barnett AH & Kumar S
          
P99 Expression of purinergic receptors in human insulin-secreting cells in health and disease
Gonzalez A-M, Shepherd RM, Lee A, Hussain K, Clayton PE, Aynsley-Green A, Lindley KJ & Dunne MJ
        
P100 A novel gender dimorphism in the response of the gonadal axis to critical illness
Jaiswal V, Baudouin SV & Ball SG
     
P101 Weight gain is not inevitable in the management of type 2 diabetes mellitus
Tuthill A, Suliman A, Curran S, McKenna M, O’Shea D & McKenna TJ
     
P102 Comparison of effect of insulin in hypothyroidism and after the thyroid hormone therapy
Stanická S, Vondra K, Pelikánová T, Vlèek P, Nìmec J, Masek Z, Skibová J & Zamrazil V
      
P103 The utility of the HOMA model for identifying women with polycystic ovarian syndrome (PCOS) who are insulin resistant
Heald AH, Whitehead S, Anderson S, Laing I & Buckler H
         
P104 Paradoxical variability of SHBG and insulin resistance in PCOS patients and controls
Jayagopal V, Kilpatrick ES, Holding S, Jennings PE & Atkin SL
        
P105 Islet amyloid polypeptide (IAPP) accumulates in lysosomes of human b-cells by crinophagy but does not form fibrils
Bhogal RK, Novials A, Gomis R, Morris JF & Clark A
    
P106 Audit on lipid management in diabetes
Moulik PK, Nethaji C, Arsalanizadeh B & Khaleeli AA
         
P107 Single nucleotide polymorphisms in the ghrelin gene in tall obese children
Gueorguiev M, O’Grady E, Grossman AB, Froguel P & Korbonits M
   
P108 Paediatric diabetes survey shows type 2 diabetes prevalence 0.4%, distinct from type 1, and associated with overweight, puberty, female sex and ethnic minority status
Barrett TG, Ehtisham S, Smith A & Hattersley AT
     
P109 ACTH stimulates insulin secretion by MIN6 mouse insulinoma cells
Al-Majed HT, Jones PM, Persaud SJ, Sugden D & Whitehouse BJ
         
P110 Intensive insulin therapy in diabetic pregnancy
Safonova OV
          
P111 Counterregulatory hormone responses to hypoglycaemia in type 2 diabetes mellitus - comparison of metformin and sulphonylurea treated subjects
Hoashi S, Cannon D, Kilbane M, Wade BM& Kinsley BT
       
P112 Complication in acute myocardial infarction and admission hyperglycaemia
Garg R, Haider Y & Agaarwal AK
      
P113 Serum lipoprotein (a) and other lipid parameters in patients with liver cirrhosis and chronic active hepatitis
Comlekci A, Kuralay F, Caliskan S, Akpinar H,Okan I, Ellidokuz E, Okan A, Topalak O, Tankurt E & Yesil S
     
P114 Lectin binding of serum hCG in pregnancy and type 1 diabetes
Nayar R, Dillon S, McNab G & Chapman AJ
        
P115 Atorvastatin decreases LDL oxidation in glucocorticoid excess state
Bayraktar F, Oge A, Ozgonul M, Ozgen AG, Sozmen E & Yilmaz C
       
P116 A pilot study of metformin for the treatment of hirsutism in patients without diabetes
Moleele GT & Sturrock NDC
        
P117 Ultrasound features of polycystic ovaries (PCO) and metabolic syndrome X
Atiomo WU, Mikhalides DP, Morris R & Hardiman P
    

Endocrine Tumours and Neoplasia

P118 Outcome of transphenoidal surgery by one surgeon for acute acromegaly
Akber M, Clayton RN & Carlin WV
       
P119 Identification of novel epigenetically silenced sequences in pituitary tumours
Simpson DJ, Cutty SJ, Clayton RN & Farrell WE
       
P120 Expression of the F-box protein Skp-2 in normal and tumorous human pituitary
Musat M, Korbonits M, Pyle M, Gueorguiev M, Powell M, Dumitrache C, Poiana C & Grossman AB
        
P121 High resolution allelotyping of adenomas identifies novel regions of genetic loss
Simpson DJ, Buch HN, Bicknell EJ, Cutty SJ, Clayton RN & Farrell WE
        
P122 Cushing’s syndrome due to apparently autonomous adrenal hyperplasia in a patient with multiple endocrine neoplasia type I
Khoo B, Field B, Rosenfelder N, Lowe DG, Beshyah SA & Monson JP
        
P123 An evaluation of endocrine assessment of patients with pituitary tumours prior to tertiary referral
Baskar V, Barton DM, Kamalakannan D & Singh BM
      
P124 Hereditary multiple exostosis due to an acceptor splice site mutation in the EXT1 gene
Lemos MC, Christie PT, Harding B, Kotanko P, Thakker RV & Javor T
      
P125 Approaches to evaluating the role of vitamin D receptor polymorphisms in breast and prostatic carcinoma
Guy M, Lowe LC, Oades G, Bretherton-Watt D, Mansi JL & Colston KW
           
P126 Treatment options for refractory hypercalcaemia in a patient with PTHrP-secreting neuroendocrine tumour and primary hyperparathyroidism
Barakat MT, Hameed A, Goodlad C, Tait P, Meeran K, Howard JK & Williams GR
     
P127 Multiple endocrine neoplasia type 1 (MEN-1) with two different pancreatic tumours
Kalavalapalli S, Barakat MT, Jackson J, Todd JF, Williams GR & Meeran K
        
P128 Cigarette smoking exposure, serum insulin-like growth factors, and cancer risk: a population-based study
Renehan AG, Gleeson H, Atkin WS, O’Dwyer ST & Shalet SM
        
P129 Hypercalcaemia associated with clear cell carcinoma of the ovary
Haq M & Simpson RD
         
P130 £31,474 saved with shared care
Thornton Jones VA, Wass JAH & Turner HE
     
P131 The pathogenesis of pancreatic b-cell adenoma does not involve defects in ATP-sensitive potassium channels
Cosgrove KE, Barnes PD, O’Brien RE, Natarajan A, Lee AT, Shepherd RM, Gonzalez AM, Hussain K, Clayton PE, Aynsley-Green A, Lindley KJ, Rahier J, Glaser B & Dunne MJ
        
P132 Do symptoms and signs of acromegaly correlate with GH during medical treatment?
Fazal-Sanderson V, Wass JAH & Turner HE
         
P133 Alterations in expression levels of ER subtypes and their coregulators in endocrine resistant breast cancer
Parkes AT, Ponchel F, Burdall S, Farmery S & Speirs V
      
P134 A role for co-regulators in estrogen receptor function
Fleming FJ, Hill AD, Duffy MJ, McDermott EW, O’Higgins NJ & Young LS
    
P135 Experience with cabergoline therapy in 34 patients with acromegaly
Rowles SV, Shalet SM & Trainer PJ
     
P136 Expression of somatostatin receptor subtypes 1, 2, 3 and 5 in the hyperplastic and neoplastic endometrium
Railton AL, Richmond I, Green VL & Atkin SL
      
P137 Do non-functioning pituitary adenomas with positive immunoreactivity for ACTH behave more aggressively than other non-functioning adenomas?
Bradley KJ, Turner HE & Wass JAH
             
P138 Chronic lymphoedema improved by the diagnosis and treatment of underlying acromegaly
Sibal L, Harris M & James RA
        
P139 The destruction box of pituitary tumor transforming gene (PTTG) mediates cell transformation
McCabe CJ, Horwitz GA, Tannahill LA, Boelaert K,Yu R, McRobbie LJ, Sheppard MC, Franklyn JA & Gittoes NJL
      
P140 Growth hormone receptor and type 1 IGF receptor in human somatotroph tumours
Kola B, Korbonits M, Powell M, Metherell L, Czirják S, Boscaro M, Mantero F & Grossman AB
      
P141 Hunting for oncogenes in pituitary adenomas - a cautionary tale of new technology
Morris D, Lillington D, Strefford J, Korbonits M, Young B & Grossman AB
         
P142 Diagnostic accuracy of ultrasound in preoperative assessment of primary hyperparathyroidism
Randall J, Malthouse S, Maddox P, Lawrence J & Robinson A
         
P143 Choice of calcitonin assay
Busbridge M, Donaldson A, Hill PA & Chapman RS
         
P144 The incidence of colorectal neoplasia in acromegaly
Kelly PA, Fairclough PD, Monson JP, Grossman AB, Chew SL, Besser GM & Jenkins PJ
        
P145 Clinical and biochemical findings in paragangliomas
Peaston RT, Ibrahim IM, Woods D, Senior PA & Perros P
          
P146 Inhibition of 11b-HSD2 has an anti-proliferative effect on pituitary tumour cells
Rabbitt EH, Bujalska IJ, Stewart PM, Sheppard MC, Hewison M & Gittoes NJL
       
P147 Reference ranges for urinary metadrenalines in patient populations
Standing SJ, Gardner SG, Shine B, Wass JAH & Turner HE
         
P148 Primary medical management of macroprolactinomas with cabergoline (CAB)
Philip S, Booth A, Abraham P, Kumaravel M, Watson WA, Park CM, Bandyopadhyay S, Acharya SH & Bevan JS
         
P149 Routine calcitonin measurement in management of thyroid nodules: a decision analysis approach
Shine B
          
P150 Patterns and mechanisms of hypercortisolism in association with phaeochromocytoma
Abraham P, Watson WA, Park CM, Philip S, Bandyopadhyay S, Acharya SH, Talbot JA, White A & Bevan JS
      
P151 Ghrelin, but not GHRP-6 or hexarelin, increases proliferation of colonic epithelium via effects on c-myc mRNA
Khalaf S, Ogunkolade BW, Kelly PA, Fairclough PD, Bustin SA & Jenkins PJ
     

Genetics
P152 No association of a 3’ UTR polymorphism of the interleukin-12 P40 (IL12B) gene with Graves’ disease in a UK population
Heward JM, Allahabadia A, Franklyn JA & Gough SCL
       
P153 Lack of association of the insulin gene region with Graves’ disease in the UK
Tait KF, Collins JE, Heward JM, Allahbadia A, Barnett AH, Franklyn JA & Gough SCL
      
P154 The angiotensin II response to an acute exercise stimulus and the angiotensin converting enzyme (ACE) genotype
Woods DR, Jones A, Sanders J, Hurel S, Jamshidi Y, Hawe E, Goldstone J, Gohlke P, Humphries S & Montgomery H
        
P155 A nonsense mutation in exon two of the DNase1 gene is not present in UK subjects with SLE and autoimmune thyroid disease
Simmonds MJ, Heward JM, Allahabadia A, Foxall H, Gordon C, Franklyn JA & Gough SCL
       
P156 Seven novel mutations in the androgen receptor gene associated with complete androgen insensitivity syndrome
Jääskeläinen JES, Mongan NP, Martin H & Hughes IA
    
P157 Compound heterozygous AIRE-1 mutations in autoimmune polyendocrinopathy type 1
Bowl MR, Turner JJO, Nesbit MA, Harding B & Thakker RV
         
P158 Lack of association between polymorphic markers within 11b-hydroxysteroid dehydrogenase type 1 gene (HSD11B1) and obesity
Draper N, Echwald SM, Sorensen TIA, Astrup A, Lavery GG, Chalder SM, Hewison M, Pedersen OB & Stewart PM
       
P159 Single nucleotide polymorphisms of the b2-adrenergic receptor (ADRB2) gene and hypertension
Brain NJR, Tomaszewski M, Lacka B, Charchar FJ, Wang W, Padhmanaban S, Anderson NH, Zukowska-Szczechowska E, Grzeszczak W & Dominiczak AF
       
P160 Independent Y chromosome markers associated with blood pressure and testosterone levels
Charchar FJ, Tomaszewski M, Padmanabhan S, Lacka B, Anderson NH, Zukowska-Szczechowska E, Grzeszczak W & Dominiczak AF
        

Growth and Development

P161 Increased heights and weights of Isfahani male children and adolescents in Iran
Aminorroaya A, Amini M, Maghdi H & Zadeh AH
      
P162 Androgen receptors are expressed in the developing antler tip and velvet skin of the red deer (Cervus elaphus)
Croft NJ & Randall VA
         
P163 Gender variation in leptin circadian rhythm and pulsatility in adult growth hormone deficiency; effects of growth hormone replacement
White HD, Ahmad AM, Guzder R, Wallace AM, Syed AA, Thomas J, Fraser WD & Vora JP
       
P164 Monitoring insulin-like growth factor-I and IGF binding protein-3 in children and adolescents on GH treatment using filter paper blood spots
Das U, Price DA, Khosravi J, Wales JKH, Butler G, Kibirige MS, Diamandi A, Jones J, Hall CM & Clayton PE
        
P165 Serum ghrelin concentrations in healthy children and adolescents
Clayton PE, Hall CM, Jones J & Whatmore AJ
      
P166 BMI corresponds to oestradiol levels and delayed puberty in boys
Chatterjee S
    
P167 An audit of paediatric to adult transition of childhood onset growth hormone deficiency
Nandlal SA, Nelson C & Conway GS
         
P168 Factors affecting insulin-like growth factor I response to growth hormone (GH) treatment in GH-deficient adults
Sathiavageeswaran M, Bisp K, Shine B & Wass JAH
         
P169 Familial combined pituitary hormone deficiency by PROP1 gene mutation, in a Portuguese family
Bacelar C, Monteiro M, Vargas G, Lemos MC, Regateiro F, Carvalheiro M & Ramos H
       
P170 A survey of the investigation of short stature in Wales
Evans C & Gregory JW
         
P171 Accelerated aortic root dilatation in Turner syndrome
Ostberg JE
         
P172 Cellular proliferation in the adrenal cortex in vitro
Whitworth EJ, Vakharia K, Vinson GP & Hinson JP
     
P173 Developmental regulation of the mt1 melatonin receptor gene in the rat pituitary gland
Johnston JD, Messager S, Barrett P & Hazlerigg DG
       
P174 Growth hormone therapy decreases LDL oxidation in oestrogen deficiency
Bayraktar F, Oge A, Ozgonul M, Ozgen AG, Sozmen E & Yilmaz C
        
P175 Abnormal collagen morphology and decreased bone strength in growth hormone deficient rats
Lange M, Qvortrup K, Svendsen OL, Flyvbjerg A, Nowak J, Olgaard K, Petersen MM & Feldt-Rasmussen U
       
P176 Growth hormone replacement: patients’ views
Carson MN, Perrin P & Wass JAH
      

Neuroendocrinology
P177 Growth hormone deficient patients over 60 years require a low dose of GH and short titration phase to achieve normal serum IGF-I levels
Mah PM, Newell-Price J, Doane A, Ibbotson V, Ho K & Ross RJ
         
P178 A relationship between interleukin-1 and interleukin-6 secretion by human pituitary adenomas in culture
Kerry KE, Borg SA & Jones TH
        
P179 Time dependency of somatotroph dysfunction following radiation damage of the hypothalamic-pituitary axis
Darzy K, Ghigo E & Shalet SM
      
P180 Ghrelin is acutely regulated by insulin but not glucose
Flanagan DEH, Evans ML, Monsod TP, Rife F, Heptulla RA, Tamborlane WV & Sherwin RS
        
P181 Gender differences in the relationship between leptin and the autonomic nervous system
Flanagan DEH, Vaile JC, Petley GW, Moore VM, Godsland IF, Cockington RA, Robinson JS & Phillips DI
        
P182 Magnetic resonance perfusion enables assessment of blood supply to pituitary gland
Turner HE, Jezzard P, Levy JC, Matthews PM, Wass JAH & Byrne JV
       
P183 Long term treatment of adult growth hormone deficiency does not normalise quality of life compared to control subjects: a need for a different strategy?
Malik IA, Groves T, Wallymahmed M, Wilding JPH & MacFarlane IA
       
P184 Expression and purification of histidine-tagged anosmin-1 by Drosophila S2 cells and Ni-NTA agarose chromatography
Hu Y, Bouloux P & MacColl G
     
P185 Cardiac sympathovagal balance correlates positively with age in growth hormone deficient (GHD) patients
Leong KS, Malik IA, Wallymahmed M, MacFarlane IA & Wilding JPH
        
P186 The pattern of green fluorescent protein (GFP) expression following intrahypothalamic injection of adeno-associated virus-GFP
Ward HL, Gardiner JV, Kong WM, Murphy KG & Bloom SR
       
P187 The effect of serotonin on the GH, T3, T4, milk production and composition
Khazali H
       
P188 Diet-induced obesity in the Sprague-Dawley (SD) rat
Archer ZA, Rayner DV & Mercer JG
       
P189 The correlation between serum insulin-like growth factor 1 levels and creatinine clearance in adults with growth hormone deficiency
        
Al-Mrayat M, Donaldson O, Anyaoka V & Johnston DG
      
P190 Functional neurosecretory GnRH deficiency in a man with adult onset hypogonadotrophic hypogonadism: an unrecognised entity?
Silveira LGF, Thomas M & Bouloux PMG
       
P191 Precipitating factors and surgical outcome in pituitary apoplexy
Levy MJ, Pollock JR, Baldeweg SE, Conway GS & Powell M
       
P192 Single centre audit of surgical outcome in Cushing’s disease
Baldeweg SE, Pollock JR, Kane P, Levy MJ, Akinwunmi J, Conway GS & Powell M
       
P193 Leptin and leptin receptors are developmentally regulated in rat pituitary
Morash BA, Imran SA, Ur E & Wilkinson M
        
P194 Influence of age on the vulnerability of the hypothalamic-pituitary axis to radiation damage
Gleeson HK, Baylis CF & Shalet SM
     
P195 Weight gain and obesity in patients with hypothalamic damage
Daousi C, MacFarlane IA & Pinkney JH
    
P196 Urinary catecholamines and catecholamine metabolites in the immediate post-operative period following coronary revascularization surgery
Syed AA, Wheatley HA, Badminton MN & McDowell IFW
        
P197 The effect of bombesin on the GH, T3, T4 and milk production and compositions
Khazali H
        
P198 Functional complement C3a receptors in the rat pituitary gland
Lewis BM, Francis K, Gasque P, Scanlon MF & Ham J
        
P199 Serum IGF-I levels and correlation with functional activity in the elderly
Jenkins PJ, Barber M, Camacho-Hubner C, Braid V, Gilmore D & Stott DJ
        
P200 Disease activity in acromegaly may be assessed four weeks after discontinuation of pegvisomant
Drake WM, Loureiro RA, Parkinson C, Roberts M, Akker SA, Monson JP, Besser GM & Trainer PJ
       
P201 Outcome of treatment for Cushing’s disease in Birmingham: the experience of a single surgeon
Dale JE, McGregor EJ, Johnson AP & Gittoes NJL
    
P202 b-adrenergic input exerts both acute and chronic effects on steroid production in H295R human adrenocortical cells
Kosti O, King PJ & Hinson JP
    
P203 Neuropeptides and adrenocortical proliferation in vitro
Whitworth EJ, Hinson JP & Vinson GP
         
P204 Growth hormone (GH) deficiency in adults treated for acute lymphoblastic leukaemia (ALL) in childhood
Ayuk J, McGregor E, Mann JR, Stewart PM & Toogood AA
      
P205 Outcomes in the management of pituitary apoplexy: a conservative approach may be prudent
McGregor EJ, Ayuk J & Gittoes NJL
             
P206 Prolactin releasing peptide does not have a significant role in the control of growth hormone secretion either in vitro or in vivo in freely moving male rats
Seal LJ, Small CJ, Wren AM, Dhillo WS, Ghatei MA & Bloom SR
     
P207 Measures of cardiovascular parameters in patients with acromegally switched from SC octreotide to Sandostatin-LAR
Smith W, Oldroyd B, Belchetz PE, Sivananthan M & Orme SM
        

Reproduction

P208 Is the antidiuretic effect of recombinant prolactin mediated by changes in the glomerular filtration rate?
Jones GG, Bagshaw L & Laycock JF
         
P209 Cardiovascular risk profiles in women with polycystic ovarian syndrome (PCOS)
Bickerton AST, Clark N, Meeking DR, Crook M, Shaw KM & Cummings MH
        
P210 Weight change and androgen levels during contraceptive treatment of women affected by polycystic ovary syndrome (PCOS)
Vrbikova J, Dvorakova K, Hill M & Starka L
          
P211 Parathyroid polyhormone action on motility of pregnant mouse uterus in vitro: role of nitric oxide
Francis M, Precious S, Brown J & Dacke CG
     
P212 Phenotype and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians (SA) and Caucasians (C): is there a difference?
Wijeyaratne CN, Balen AH, Barth J & Belchetz PE
        
P213 Detection of bio-inactive prolactin (macroprolactin) is analyser dependant
Smith TP, Suliman AM, Fahie-Wilson MN & McKenna TJ
       
P214 Awareness of Libyan women of the menopause and their attitudes to hormone replacement therapy
Beshyah SA, Bay NA & Sherif IH
  
P215 The mRNA expression and regulation of natural antimicrobials in human fetal membranes and placenta
King AE, Riley SC & Kelly RW
  
P216 Activation of supraoptic nucleus (SON) oxytocin neurones during mouse parturition
Douglas AJ & Willen S
      
P217 Residual ovarian function after cytotoxic chemotherapy and possible predictors of ovarian recovery
Howell SJ, Radford JA, McNeilly AS & Shalet SM
        
P218 A randomised controlled trial comparing the use of metformin and dianette in hirsutism associated with PCOS
Harborne L, Fleming R, Lyall H & Norman J
        
P219 Testicular Leydig cell tumour presenting as primary infertility
Markou A, Vale J & Franks S
      
P220 Phytoestrogens as inhibitors of aromatase and 17b-hydroxysteroid dehydrogenase type 1 in luteinized human granulosa cells
Lacey M & Whitehead SA
           
P221 Oxygen tension regulates placental 11b-hydroxysteroid dehydrogenase type 2
Driver PM, Hewison M, Kilby MD & Stewart PM
       
P222 Androgen status and female sexual dysfunction in healthy pre-menopausal women
Nyunt A, Stephen G, Fielding A, Wheeler M, Gibbin J, Durgan L & Price DE
       
P223 A novel sensitive radioimmunoassay for the measurement of soluble Flt-1 (soluble vascular endothelial growth factor receptor-1)
McKeeman G, Ardill J, Caldwell C, McFerran N, Greer B & McClure N
        
P224 Improvement of hyperandrogenism and insulin resistance in females with severe obesity after weight loss through bariatric surgery
Monteiro M, Cardoso H, Vargas G, Pichel F, Pereira IA, Sergio A, Santos MJ, Bravo F, Santos C & Ramos H
       
P225 Oral clatharate-DHEA as a potential form of androgen replacement in hypogonadal men. A phase 2, open label, placebo controlled, parallel group pharmacokinetic study
Oxynos C, Phillips JM, Laing I, Saad F & Wu FCW
        
P226 Significant ethnic variation in circulating total bound and free testosterone
Heald AH, Bethell F, Anderson S, Owen D, Laing I, Gibson JM & Cruickshank JK
        
P227 Increased HOXA10 expression in late gestation: a novel target for hormonal regulation in placenta and decidua
Evans KN, Driver PM, Zehnder D, Bulmer JN, Stewart PM, Kilby MD & Hewison M
       
P228 Efficacy of metformin for ovulation induction in polycystic ovary syndrome
Tsilchorozidou T, West C, Parikh B, Davies M & Conway GS
        
P229 Expression of mRNA for IGF-1, IGF-2, type 1-IGF receptor, type 2-IGF receptor and insulin receptor in isolated, human preantral follicles
Rice S, Taylor D, Margara R, Franks S & Hardy K
        
P230 FSH alters metabolism and increases chromosomal abnormalities in mouse cumulus-oocyte-complexes matured in vitro
Roberts R, Iatropoulou A, Franks S & Hardy K
      
P231 Engineering of single chain antibodies selected from a phage display library into human IgGs that recognise gonadotrophin surge-attenuating factor (GnSAF) bioactivity
Sorsa-Leslie T, Harris WJ, Mason HD & Fowler PA
          
P232 1,25-dihydroxyvitamin D3 receptors (VDR) are present on human granulosa cells and cells of the corpus luteum
Brain HPS, Bano G, Murray J, Nussey SS & Mason HD
        
P233 Semen profile, hormonal analysis and physiological activity of Pakistani men with varying degrees of sperm concentrations
Tahir F, Subhan F, Sultan S, Kazi BM, Saeed Dil A, Ahmed MM & Afzal M
       
P234 Effectiveness of antioxidant vitamin therapy in improving semen quality
Tahir F, Subhan F, Sultan S, Kazi BM, Saeed Dil A, Ahmed MM & Afzal M
        
P235 Regulation of expression and activity of lysyl oxidase in developing ovarian follicles
Rae MT, Harlow CR, Davidson L & Hillier SG
       

Signalling
P236 Do inhibitors of NAD(P)H oxidase improve endothelial function in rat and human arteries?
Hamilton CA, Brosnan MJ & Dominiczak AF
        
P237 Analysis of GR/NFkb interactions in living cells
Garside HJ, Stevens A & Ray DW
         
P238 Interactions of vitamin D analogues with downstream effectors of insulin-like growth factor 1 (IGF-I) signalling
Lowe LC, Mørk Hansen C & Colston KW
        
P239 Dexamethasone blocks mitochondrial targeting-induced apoptosis
Newton CJ, Bilko D, Adams IP, Ran J, Green V & Atkin SL
        
P240 Expression and function of voltage-gated calcium channels in human pancreatic b-cells in health and disease
Natarajan A, Cosgrove KE, Shepherd RM, O’Brien RE, Gonzalez A-M, Lindley KJ, Clayton PE, Aynsley-Green A & Dunne MJ
        
P241 Mutations in the growth hormone receptor (GHR) may differentially affect signalling and receptor trafficking
Milward A, Wilkinson I, Webb S, Metherell L, Camacho-Hubner C, Savage M, Chew S, Akker S, Clark A & Ross R
      
P242 Essential role of p38 mitogen-activated protein kinase in adipogenesis
Patel NG, Holder JC, Smith S, Kumar S & Eggo MC
         

Steroids

P243 Free cortisol index in suspected HPA axis pathology
LeRoux C, Dhillo W, Kong WM, Chapman G, Jones J & Alaghband Zadeh J
    
P244 Expression and corticosteroid regulation of serum and glucocorticoid regulated kinase, and epithelial sodium channel subunits in human ocular ciliary epithelium
Rauz S, Walker EA, Hughes SV, Coca-Prados M, Hewison M, Murray PI & Stewart PM
          
P245 Carbenoxolone, an inhibitor of 11b-hydroxysteroid dehydrogenase type 1, reduces intraocular pressure in patients with ocular hypertension
Cheung CMG, Rauz S, Murray PI & Stewart PM
     
P246 Comparison of the efficacy of long-term self-administration of subcutaneous human chorionic gonadotrophin with intramuscular exogenous testosterone (Sustanon) in male hypogonadism
Caddy SJ & Jones TH
     
P247 The prevalence and morbidity of long-term oral corticosteroid therapy
Mackie JH, Cooper MS & Stewart PM
               
P248 The relationship between smoking, statin therapy and testosterone in men with coronary artery disease
Morris PD, Pugh PJ, Hall J, Channer KS & Jones TH
      
P249 Androgens and diabetes mellitus in men with coronary artery disease
Morris PD, Pugh PJ, Roberts SA, Channer KS & Jones TH
  
P250 Testosterone and pro-inflammatory cytokines in men with chronic heart failure
Hall J, Pugh PJ, Jones RD, Corlett G, Channer KS & Jones TH
       
P251 Testosterone therapy improves depressive symptoms in men with chronic heart failure
Pugh PJ, Jones RD, Hall J, Channer KS & Jones TH
      
P252 Testosterone increases interleukin 10, an anti-inflammatory cytokine, in whole blood from hypogonadal men
Corlett GL, Pugh PJ, Kapoor D, Jones RD, Channer KS & Jones TH
      
P253 Testosterone and skeletal muscle parameters in men with chronic heart failure
Pugh PJ, Jones RD, Hall J, Channer KS, Jones TH & van Beek E
      
P254 Hypoglycaemia and Addison’s disease - cause or association?
Kennedy A, Hadden DR & Hunter SJ
      
P255 Intermittent hyponatraemia due to isolated ACTH deficiency
Ajjan R, Scott E, Ismail A, Walker P & Nagi DK
     
P256 Expression of adipose 11b-hydroxysteroid dehydrogenase type 1 in human obesity
Tomlinson JW, Sinha B, Hewison M & Stewart PM
      
P257 Enhanced hepatic A-ring reduction of glucocorticoids in obesity: regulation by glucocorticoids and insulin
Livingstone DEW, McInnes KJ, Walker BR & Andrew R
        
P258 In vitro expression of catalytically active human aldosterone synthase
Inglis GC, Davies E, Stewart PM, Fraser R & Connell JMC
      
P259 Reduced glucocorticoid receptor expression in obese Zucker rats: protection from the metabolic consequences of obesity?
Drake AJ, Cleasby ME, Livingstone DEW, Seckl JR & Walker BR
    
P260 Assessment of mineralocorticoid status by urinary corticosteroid profiling using gas chromatography-mass spectrometry (GCMS)
Shakerdi L, Fraser R & Wallace AM
        
P261 Angiotensin II and ACTH differentially regulate adrenal steroid production through key steroidogenic enzymes
Kelly SN, Smith TP, Cunningham SK, Young LS & McKenna TJ
       
P262 A role for nur-77 in the regulation of adrenal steroid production
Kelly SN, Smith TP, Cunningham SK, McKenna TJ & Young LS
         
P263 Growth hormone increases fat mass in patients with simple obesity
Tomlinson JW, Crabtree N, Clark PMS, Holder G, Shackleton CHL & Stewart PM
         
P264 Cortisone reductase (11b-hydroxysteroid dehydrogenase type 1) deficiency presenting with features of late onset congenital adrenal hyperplasia
Laing I, Adams JE, Wood PJ, Taylor NF & Ray DW
     
P265 Phytoestrogen dietary supplementation does not alter serum IGF-1 levels in postmenopausal women
Jayagopal V, Albertazzi P, Kilpatrick ES, Jennings PE & Atkin SL
      
P266 Testosterone exhibits a calcium antagonistic action upon store operated calcium channels in cultured vascular smooth muscle cells
Jones RD, Ruban LN, Pugh PJ, English KM, Channer KS & Jones TH
         
P267 Testosterone does not increase the production of cyclic AMP (cAMP) in cultured vascular smooth muscle cells
Ruban LN, Jones RD, Pugh PJ, English KM, Channer KS & Jones TH
        
P268 Circulating steroid levels in the testicular feminised (Tfm) mouse
Jones RD, Hall J, Pugh PJ, English KM, Channer KS & Jones TH
      
P269 Size at birth, gestational age and cortisol secretion in adult life: do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?
Kajantie E, Phillips DIW, Dunkel L, Andersson S, Barker DJP, Forsen T, Osmond C, Wood PJ, Tuominen J & Eriksson J
        
P270 Roles of k-ras and Gadd153 in 17b-oestradiol-induced apoptosis in colo205 cells
Qiu Y, Langman MJS & Eggo MC
       
P271 Fetal and maternal regulation of aldosterone synthase and 11b-hydroxylase
Lo YC, Mason JI, Williams BC, Lloyd-MacGilp SA & Kenyon CJ
      
P272 Quantification of aldosterone synthase (CYP11B2) gene expression in the adrenal gland and central nervous system following dietary sodium manipulation
Ye P, Kenyon CJ, Mackenzie SM, Fraser R, Connell JMC & Davies E
       
P273 Long-term overall success after transsphenoidal surgery for Cushing’s disease: time for a reappraisal of therapy?
Kennedy A, Wiggam MI, Hadden DR, McCance DR, Sheridan B & Atkinson AB
      
P274 What value do cortisol measurements provide in monitoring metyrapone therapy?
Wieringa G, Naing S, Perry LA, Anderson JM, Wiener K, Burrows GC, Warburton R, Kane JW & Trainer PJ
     

Thyroid
P275 Atrial fibrillation predicts mortality in thyrotoxicosis
Osman F, Daykin J, Sheppard MC, Gammage MD & Franklyn JA
       
P276 Increased force/unit cross sectional area as well as increased bulk causes recovery in proximal strength in hyper/hypothyroidism
Khaleeli AA & Houghton T
      
P277 Influence of pre-treatment factors on outcomes following the use of high fixed dose radioiodine treatment for hyperthyroidism
Barton DM, Buch HN, Baskar V, Kumar H & West TET
       
P278 The female preponderance to autoimmune thyroid disease is reduced in multiplex type 1 diabetes families
Tait KF, Berman J, Carr-Smith J, Rowe B, Heward JM, Franklyn JA, Todd JA, Bain SC, Barnett AH & Gough SCL
      
P279 Analysis of a clinical workstation thyrotoxicosis share-care scheme
Chatterjee S, Kieffer V & Howlett TA
       
P280 Thyrotoxic heart failure in a previously fit 40 year old woman
Banerjee M, Javaid K, Khan S & Vice PA
      
P281 Delayed resolution of endothelial dysfunction despite biochemical correction of thyrotoxicosis
Obuobie K, Evans SA & Lazarus JH
P282 Thyroid function in paediatric patients with malignancy after radiotherapy in Isfahan, Iran
Hashemipoor M, Golpaiegani F, Babazadeh S, Maafi AR, Javanmardy GA & Iranpour R
      
P283 Thyroid hormone (TH) regulation of iodothyronine deiodinase and thyroid hormone receptor (TR) expression in placental trophoblast cells
Hobbs EL, Driver P, McCabe CJ, Franklyn JA & Kilby MD
      
P284 Pituitary tumor transforming gene and basic fibroblast growth factor-2 - novel potential molecular indicators for thyroid cancer
Boelaert K, McCabe CJ, Tannahill LA, Gittoes NJL, Eggo MC, Watkinson JC, Sheppard MC & Franklyn JA
      
P285 Outcome at two years of fixed dose radioiodine treatment for thyrotoxicosis
Forde I, Corgie D & Trainer PJ
       
P286 Effect of blood exchange transfusion on neonatal thyroid function
Iranpour R, Hashemipoor M, Haghshenas I, Hamidi M & Heydarzadeh A
       
P287 Provision of a new strength thyroxine tablet would facilitate tight control of TSH concentrations in primary hypothyroidism
Bhala N, Weetman AP & Jenkins RC
      
P288 The follow-up status of patients 10 years after treatment with radioactive iodine (RI) for hyperthyroidism
Varghese B & Trainer PJ
   
P289 A cluster of cases of subacute thyroiditis in north east England
Craig FE, Frewin S & Perros P
      
P290 Audit of the management of maternal hypothyroidism in pregnancy: implications for service provision
Hannon T, Sturgiss S & Ball SG
        
P291 Lithium associated thyrotoxicosis
Ghosh S & Bangar V
        
P292 Thyroid dysfunction in diabetes: can we justify routine screening?
Moulik PK, Nethaji C & Khaleeli AA
      
P293 Clinical assessment of two methods for measuring thyrotropin binding inhibiting immunoglobulin (TBII)
Schardt CW, Perros P, Fleetwood A, Self C & Weightman DR
P294 Thyroid peroxidase antibodies are not a surrogate for thyroid stimulating antibodies in the investigation of the etiology of thyrotoxicosis
Evans C, Alkhafaji F, Selwood C & Ludgate M
       
P295 Molecular characterisation of congenital hypothyroidism
Jordan NJ, Gregory J, Evans C, Williams NM, Owen MJ & Ludgate Mv
     
P296 Pyrimidine and purine metabolism in human leukocytes in autoimmunological thyroid diseases - RNA expression of some enzymes
Lewinski A, Brzezianska E, Karbownik M, Zasada K, Migdalska-Sek M & Pastuszak-Lewandoska D
      
P297 Protein kinase C delta interacts with the sodium iodide symporter (NIS) to increase its activity in human thyrocytes
Turner FE & Eggo MC
       
P298 Profile of the thyroid function in a population with type-2 diabetes mellitus
Nobre EL, Jorge Z, Pratas S, Silva C & Castro JJ
         
P299 Thyroid function in early pregnancy. A prospective study
Bohnet HG & Martens K
      
P300 Determining the molecular causes of hyperthyroidism
Al-Khafaji F, Baker G & Ludgate M
        
P301 Telephone follow-up following radioiodine therapy for thyrotoxicosis improves outcome
Murphy E, Mehta S, Gannon D, Bassett JHD, Frank J & Meeran K
       
P302 Environmental factors produce variation within a model of thyroid eye disease
Baker GRC & Ludgate M
        
P303 The use of lithium as an adjunct to radioiodine therapy for thyrotoxicosis
Murphy E, Bassett JHD, Frank J & Meeran K
       
P304 Adenoviral expression of secreted Tie-2 reduces thyroid follicular cell growth and adhesion
Ramsden JD, Mautner V, Watkinson J & Eggo MC
       
P305 Primary hypothyroidism and unilateral thyroid eye disease: a case report
Ozgen AG, Terzioglu E, Duman E & Kabalak T
    
P306 Plasma total and free tissue factor pathway inhibitor, tissue plasminogen activator antigen, and plasminogen activator inhibitor antigen levels in various thyroid disorders
Comlekci A, Ozcan MA, Demirkan F, Sari I, Demir T, Ozsan H, Oruk G & Yesil S
       
P307 High thyroglobulin autoantibodies in Sri Lankan Tamil tea workers exhibit an epitope-recognition pattern distinct from healthy subjects and autoimmune thyroid disease (AITD) patients
Okosieme OE, Parkes AB, Premawardhana LDKE, Ruf J, Carayon P & Lazarus JH
     
P308 Thyroid disease in patients with genetic haemochromatosis - a prospective study
Murphy MS & Walsh CH