23rd Joint Meeting of the British Endocrine Societies

Programme: Attended Posters

Sun 21 & Mon 22 Mar | Tues 23 Mar | Wed 24 Mar | Attended Posters

Acrobat Icon Download Programme (pdf) (878kb)


Posters will be on display in Hall D. Please note that even-numbered posters will be attended on Tuesday 5 April at 11.45-13.00 and odd-numbered posters will be attended on Wednesday 6 April at 11.45-13.00.

Posters will be on display in the Main Foyer and Hewison Hall. Please note that even-numbered posters will be attended on Tuesday 23 March at 12.00-13.00 and odd-numbered posters will be attended on Wednesday 24 March at 12.00-13.00.

Bone Reproduction
Comparative endocrinology Steroids
Cytokines and growth factors Thyroid
Diabetes, metabolism and cardiovascular Clinical case reports
Endocrine tumours and neoplasia Clinical practice
Growth and development Novartis Awards Poster Session
Neuroendocrinology and behaviour  


Bone
P1 Failure to normalise PTH during the treatment of osteomalacia
Peacey SR, Wright D & Harries MJ
 
P2 Does leptin regulate bone turnover in adult growth hormone deficiency?
Joseph F, Ahmad AM, Wallace AM, White HD, Durham BH, Fraser WD & Vora JP
 
P3 Oral bisphosphonates may reverse the decline in bone mineral density in adults with cystic fibrosis
Cawood TJ, Smith D, Wen YC, Gibney J, Dodd JD, Au-Yeoung ML, McKenna M, Fitzgerald O, Gallagher C & O'Shea D
 
P4 The role of the growth hormone-insulin-like growth factor-I (GH-IGF-I) axis in the aetiology of male idiopathic osteoporosis
Patel MBR, Arden NK, Masterson L, Phillips DIW, Swaminathan R, Syddall HE, Wood PJ, Cooper C & Holt RIG
 
P5 Growth hormone replacement is important for the restoration of PTH circadian rhythmicity in older adult growth hormone deficient patients
White HD, Ahmad AM, Joseph F, Prabhakar VKB, Patwala A, Whittingham P, Durham BH, Fraser WD & Vora JP
 
P6 Parathyroid hormone and phosphate circadian rhythms are altered in osteopaenic adult growth hormone deficient patients
White HD, Ahmad AM, Joseph F, Chandran S,Corlett P, Durham BH, Fraser WD & Vora JP
 
P7 Transdermal testosterone replacement in men with evidence of borderline gonadal failure
Merza Z, Mah PM, Blumsohn A, Meads D, McKenna S, Wylie K, Eastell R & Ross RJM
 
P8 Application of new indices of bone activity for evaluation of the response to treatment of hyperthyroidism and Paget's disease
Smith D, Murray B, Gibney J, O'Shea D & McKenna TJ
 
P9 Outcome of parathyroidectomy for primary hyperparathyroidism in 249 consecutive patients
Ma YT, Toogood AA, Campbell D, Ready AR & Gittoes NJL
 
P10 Inactivating progesterone metabolism in human osteoblasts
Kaur K, Cooper MS, Arlt W, Stewart PM, Hewison M & Quinkler M
 
P11 Utility of biochemical screening in the context of evaluating patients with a presumptive diagnosis of osteoporosis
Rajeswaran C, Spencer J & Orme SM
P12 Investigation of seasonal reference intervals for 25-cholecalciferol (vitamin D)
Donaldson A, Leung YH, Jackson DA, Hill PA & Chapman RS
P13 The role of local corticosteroid generation in inflammation-associated bone loss
Cooper MS, Filer A, Moore J, Emery P, Buckley CD, Hewison M & Stewart PM
P14 Adenosine stimulates IL-6 but inhibits osteoprotegerin secretion by osteoprogenitor cells
Evans BAJ, Elford C & Ham J
P15 Growth retardation following prenatal GC exposure is more pronounced in the female offspring and is associated with raised serum IGF-I
Mushtaq T, Farquharson C, Nyirenda M, Seawright E, Seckl J & Ahmed SF
Comparative endocrinology
P16 Developmental changes in gonadal and adrenal steroidogenesis in the blue fox (Alopex lagopus)
Osadchuk LV, Braastad BO, Hovland AL & Bakken M
P17 An appraisal of biochemical assessment of hypogonadism and bio-available testosterone in adult men
Malkin CJ, Morris PD, Channer KS & Jones TH
P18 Usefulness of ultrasonography in girls with true precocious puberty before and after two years of treatment with an LH-RH analogue
Zosi P, Triantafyllidis G, Nikolaidou A, Karakaidos D, Varhalama F, Kokori E & Karis C
P19 Changes in bone mineral density in response to growth hormone replacement in adults with isolated growth hormone deficiency compared with multiple pituitary hormone deficiencies
Waterhouse M, Laureiro R, Walker D, Besser GM & Monson JP
Cytokines and growth factors
P20 Glucocorticoids suppress macrophage migration inhibitory factor (MIF) expression in a cell-type specific manner
Alourfi Z, Donn R, Stevens A & Ray DW
P21 Responsiveness to growth hormone throughout the menstrual cycle
Gleeson HK & Shalet SM
P22 The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men
Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS & Jones TH
P23 Effects of estrogen on leptin signalling and leptin-induced TNF-alpha production
Fazeli M, Zarkesh-Esfahani SH, Maamra M & Ross RJM
P24 Excessive daytime sleepiness associated with hypercytokinaemia in POEMS
Wong SPY, Cresswell P, English P, Wilding JPH, Huda M, Pazmany L, Pinkney JH & Hart IK
P25 Effects of long term growth hormone replacement on leptin and body composition in adult growth hormone deficiency
Joseph F, Ahmad AM, Wallace AM, White HD, Durham BH, Fraser WD & Vora JP
P26 GHR-GPI insertion into target CHO cell membranes
Gavalas NG, Zarkesh-Esfahani H, Wilkinson IR, Pradhananga SL, Beghadi C, Baumann GP, Wu Z, Artymiuk PJ, Sayers JR & Ross RJM
P27 Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: relationship to type and tumour behaviour
Garcia de la Torre N, Buley I, Wass JAH, Jackson DG & Turner HE
P28 Adrenomedullin mRNA and peptide content are increased in skin following wounding
Renshaw D, Kapas S & Hinson JP
P29 Basic fibroblast growth factor (FGF2) in hypothalamus, neurohypophysis and choroid plexus: dehydration supports a putative linkage with arginine vasopressin and fluid balance
Gonzalez AM, Taylor WM, Stopa EG, King JC, Duncan JA, Baird A & Johanson CE
P30 Comparison of IL-1 alpha induced gene expression in normal human ovarian surface epithelial cells and ovarian cancer cells
Gubbay O, Guo W, Rae MT, Niven D & Hillier SG
P31 Thyroid hormone regulates heparan sulphate proteoglycans in the growth plate
Bassett JHD, Swinhoe R & Williams GR
P32 Urinary human chorionic gonadotrophin (hCG) associated proteins: isolation and characterisation by peptide identification mass spectrometry
Iles RK, Malatos S, Butler SA, Neubert H & Kicman AT
Diabetes, metabolism and cardiovascular
P33 Non-alcoholic fatty liver disease among Saudi type-2 diabetics attending medical outpatient clinic
Akbar DH & Kawther AH
P34 The effect of DHT on the regulation of therenin-angiotensin system in human abdominal subcutaneous adipocytes: implications for PCOS
Harte AL, Fowler AE, Rodriguez-Cuenca S, Chetty R, Fisher FM, Anderson LA, Roca P, Kumar S, Matyka K & McTernan PG
P35 The effect of body mass index on duration of intensive care stay and in-hospital mortality after cardiac surgery in an Irish centre
Cawood TJ, O'Shea D, Dowd N, McGovern E, Tolan M, Young V, O'Connell M & Lyons FM
P36 A7r5 rat aortic vascular smooth muscle cell apoptosis is reduced by testosterone
Kerry KE, Clark S, Jones RD, Channer KS & Jones TH
P37 Mitogen-induced apoptosis in A7r5 rat aortic vascular smooth muscle cells is not effected by testosterone
Kerry KE, Clark S, Jones RD, Channer KS & Jones TH
P38 Reduced insulin content and secretory capacity in the adult offspring of rats exposed to a high fat diet in pregnancy
Persaud SJ, Taylor PD, Poston L, Asare-Anane H, Burns CJ & Jones PM
P39 A randomised controlled trial of laser treatment among hirsute women with polycystic ovary syndrome
Clayton W, Lipton M, Sherr L, Rustin M & Elford J
P40 Understanding the fetal origins of the metabolic syndrome and its amplification by obesity; high fat feeding potentiates the programming of hepatic insulin resistance by antenatal dexamethasone in rats
Drake AJ, Raubenheimer PJ, Seckl JR & Walker BR
P41 The N363S polymorphism of the glucocorticoid receptor in South Asians in the north east
Syed AA, Irving JAE, Redfern CPF, Hall AG, Unwin NC, White M, Bhopal RS, Alberti KGMM & Weaver JU
P42 PYY deficiency may reinforce obesity
Le Roux CW, Aylwin SJB, Batterham RL, Borg CM, Wynne K, Hunt C, Coyle F, Ghatei MA, Patel A & Bloom SR
P43 Improvements in glucose utilisation immediately following exercise in patients with and without type 2 diabetes seem to be independent of improvements in insulin sensitivity
MacDonald AL, Harrison M, Bone AJ & Watt PW
P44 Effect of size at birth on glucose tolerance in pigs at 5 months of age
Perkins KS, Laws J, Litten JC, Corson AM & Clarke L
P45 Transcriptional interference by novel human PPARgamma mutants associated with lipodystrophic insulin resistance
Agostini M, Schoenmakers E, Smith AG, Szatmari I, Rajanayagam O, Savage DB, Mitchell C, Clarke M, Zalin AM, Trembath RC, Kumar S, Schwabe JWR, Nagy L, O'Rahilly S, Gurnell M & Chatterjee VKK
P46 Single nucleotide polymorphisms within oxidative stress genes affect arterial compliance: gene function relationships
Drummond RS, Brosnan MJ, Tan C, Kirk A, Hamilton CA, Connell JMC & Dominiczak AF
P47 A novel non-steroidal inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 improves features of metabolic syndrome in murine disease models
Thieringer R, Balkovec JM, Chen HY, Frazier E, Le Grand CB, Li Z, Metzger JM, Mundt SS, Nunes CN, Strowski M, Olson SH, Robertson N, Strack AM, Schaeffer JM, Wright SD, Zhang BB & Hermanowski-Votska A
P48 Mechano-receptors and cell-to-cell communication in the human collecting duct: functional involvement of TRPV4 and connexin-43
Hills CE, Wheelans DC, Ronco PM, Bland R & Squires PE
P49 Increased C-jun N terminal kinase (JNK) activity may link insulin resistance and inflammation in human central obesity
Fowler AE, da Silva NF, Burman C, Harte AL, McTernan PG & Kumar S
P50 Circulating pro-inflammatory cytokines and epicardial expression of resistin and TNF-alpha are increased in patients with cardiovascular disease
Baker AR, Quinn DW, da Silva NF, McTernan CL, Harte AL, Bonser RS, Kumar S & McTernan PG
P51 Relation of plasma homocysteine levels to atherosclerotic vascular disease and inflammation markers in type 2 diabetic patients
Akalin A, Alatas O, Colak O, Sahin F & Efe B
P52 The IGF system influences prevalence of the metabolic syndrome in a population with high rates of cardiovascular disease
Heald AH, Anderson SG, Vyas A, Patel J, Siddals KW, Cruickshank JK & Gibson JM
P53 Investigation and management of severe hyponatraemia - cause for concern?
Huda MSB, Gill GV, Wile D, Skagen K, Boyd A, Watson ID & van Heynigen C
P54 TLR mediated activation of the innate immune response in human adipocytes with associated down-regulation of adiponectin secretion and elevated TNF-alpha and IL-6 levels
Fisher FFM, Creely S, Burman C, Harte AL, Chetty R, Valsamakis G, McTernan PG & Kumar S
P55 Expression of mineralocorticoid effector mechanisms in renal biopsies of patients with severe proteinuria
Quinkler M, Zehnder D, Lepenies J, Hughes S, Lipkin GW, Hewison M & Stewart PM
P56 Testosterone regulates renal expression of the alpha-subunit of the epithelial sodium channel (alpha-ENaC)
Quinkler M, Bujalska IJ, Kaur K, Hughes S, Hewison M & Stewart PM
P57 Protective effects of phytoestrogens against oxidative stress in human endothelial cells
Zhong W, Adams IP, Adams RL & Atkin SL
P58 Targeted RNA interference to selectively modulate expression of PPARgamma2 and -1 isoforms
Schoenmakers E, Hadaschick DH, O'Rahilly S & Chatterjee VKK
P59 Quantitative analysis of glucose and insulin sensing genes in the hypothalami of Zucker diabetic fatty (ZDF) rats
Gyte AC, Pritchard LE, Brennand JC & White A
P60 Increased aromatase expression in human subcutaneous adipose tissue in obesity
Wake DJ, Elferink C, Rask E, Westerbacka J, Livingstone DEW, Soderberg S, Yki-Jarvinen H, Olsson T, Andrew R & Walker BR
P61 PPARgamma2 and RXRalpha are required for the transcriptional activation of the melanocortin 2 receptor during adipocyte differentiation
Noon LA, Clark AJL & King PJ
P62 Physiological concentrations of testosterone inhibit extracellular calcium entry via voltage-gated calcium channels in A7r5 vascular smooth muscle cells
Hall J, Jones RD, Kang P, Channer KS, Peers C & Jones TH
P63 Testosterone inhibits Ca2+ currents in A7r5 vascular smooth muscle cells, and in HEK293 cells stably expressing the alpha1C subunit of L-type Ca2+ channels (CaV1.2) and alpha1H T-type Ca2+ channels (CaV3.2)
Scragg JL, Jones RD, Channer KC, Jones TH & Peers C
P64 High prevalence of low testosterone in men with type 2 diabetes and an association with glycaemic control and obesity
Kapoor D, Aldred H, Channer KS & Jones TH
P65 Leptin increases lipid peroxidation in the mouse brain
Kutlu S, Canpolat S, Yasar A, Tuzcu M, Aydin M & Baydas G
P66 Testosterone-induced vasodilatation of isolated human mesenteric and pulmonary resistance arteries is independent of the vascular endothelium
Jones RD, Rowell KO, Pugh PJ, Shorthouse AJ, Adam IA, Vaughan R, Rocco G, Hopkinson DN, Channer KS & Jones TH
P67 Evaluation of the in-house radioimmunoassay method for peptide YY (PYY)
Vincent RP, le Roux CW, Ghatei MA & Bloom SR
P68 Diastolic blood pressure, waist circumference and cardiovascular disease in patients with obesity and type 2 diabetes
Tuthill A, Tuthill V, Barrett C, McKenna M, O'Shea D & McKenna TJ
P69 Diabetes risk in Turner syndrome - a unique metabolic defect?
Ostberg JE, Attar J, Mohamed-Ali V & Conway GS
P70 The metabolic syndrome is common in type 2 but uncommon in type 1 diabetes mellitus
Al-Saraj F, McDermott JH, McAteer S, Ali M,Tormey W & Sreenan S
P71 Diabetes knowledge deficits in adolescents and young adults with type 1 diabetes mellitus
Khamis A, Hoashi S, Duffy G, Forde R, Vizzard N, Keenan P, Cregan D, Firth RGR & Kinsley BT
P72 Maternal serum hCG binding to immobilised wheat germ agglutinin in women with and without type 1 diabetes mellitus
Nayar R, Harris J, Marley L & Chapman J
P73 A comparison of the impact of exercise in Asian and Caucasian women with polycystic ovary syndrome
Banerjee A, Bano G & Kaushal R
P74 Exercise instruction in patients with type 2 diabetes and obesity: a randomised controlled trial
Tuthill A, Quinn A, McColgan D, McKenna M,O'Shea D & McKenna TJ
P75 Characteristics and outcome of severe hyponatraemia - a case control study
Gill GV, Huda MSB, Wile D, Boyd A, Skagen K, Watson ID & van Heynigen C
Endocrine tumours and neoplasia
P76 Galectin-3 staining of benign and malignant thyroid lesions - is it a useful diagnostic tool?
Davies R, Barakat M, Meeran K & Dina R
P77 A case of severe Cushing's disease in a treated non-functioning pituitary adenoma with difficult medical management
Akber M, Muza TR & Clayton RN
P78 Proliferation of colon cancer cell line and parathyroid hormone-related peptide gene
Alokail MS
P79 Is there an ultra-short loop feedback of ACTH on itself?
Sharma M, Nanzer AM, Morris DG, Adams EF, Korbonits M & Grossman AB
P80 FSH-secreting pituitary gonadotroph adenoma producing ovarian hyperstimulation
Norris AJ, Hay C, Wilding M, McDowell G, Laing I, Holland JP, McNeilly JR, McNeilly AS & Davis JRE
P81 Deacetylating agents as mediators of iodide uptake and efflux in thyroid and breast
Clarke C, Burbridge E & Smyth PPA
P82 Over-expression and over-activation of protein kinase B/Akt in human pituitary tumours
Musat M, Korbonits M, Kola B, Nanzer A, Morris DG, Coculescu M & Grossman AB
P83 An audit of acromegaly in North-East Scotland: increased use of medical therapy enables preservation of pituitary function
Viswanath AK, Booth SA, Abraham P & Bevan JS
P84 The cyclin E specific F-box protein archipelago is over-expressed in pituitary tumours
Morris DG, Bonner SE, Korbonits M & Grossman AB
P85 Urinary free metadrenalines provide the best diagnostic biochemical test for phaeochromocytoma; experience in a tertiary care centre
Boyle JG, Davidson DF & Connell JMC
P86 A clinic for multiple endocrine neoplasia highlights needs for greater family awareness of type 1 MEN and for genetic testing of other family members
Pinkney JH, MacFarlane IA, Ellard S & Cave-Bigley D
P87 Association between serum insulin-like growth factor-I and serum growth hormone levels across an oral glucose tolerance test in assessing disease activity in acromegaly
Ayuk J, Stewart SE, Sheppard MC & Stewart PM
P88 Ovarian stromal luteoma - a rare cause of postmenopausal virilization diagnosed by selective ovarian venous sampling
Nag S, Cruickshank D, Jackson T, Leen B & Kelly W
P89 The GnRH test in the assessment of patients with pituitary and parapituitary lesions. Results of a 5-year retrospective study
Chammas NK, Chambers S & Harris PE
P90 Adrenal incidentalomas and insulin resistance - a simple coincidence or a complex syndrome?
Zieleniewski W
P91 Should post hypophysectomy patients be discharged on steroids? The use of 0900h-cortisol measurements as a screening test for pituitary-adrenal dysfunction
Walker JN, Nickerson E, Gardner SG, Shine B, Turner HE & Wass JAH
P92 Inhibition of cell proliferation, but lack of antiangiogenic effect on GH-secreting pituitary adenomas treated with Lanreotide
Garcia de la Torre N, Sullivan N, Fazal-Sanderson V, Nagy Z, Wass JAH, Ansorge O & Turner HE
P93 A new operation for adrenal pathology: laparoscopically-assisted mini-adrenalectomy
Abdel-Rahamn AT, Laban CA, Besser GM, Monson JP, Grossman AB, Savage MO, Jenkins PJ, Drake WM, Chew SL, Ashby M & Carpenter R
P94 Somatostatin and VEGF expression within the larynx
Bedford KJ, MacDonald AW, Condon L, Stafford N & Atkin SL
P95 The effects of surgery and tamoxifen on serum IGF-I and IGFBP-3 levels in breast cancer
McVittie CJ, McCarthy K, Laban CA, Miraki-Moud F, Camacho-Hubner C, Bustin SA, Carpenter R & Jenkins PJ
P96 Results of different primary treatment procedures for acromegalic patients
Ozbey N, Gjergji D, Sertkaya A, Kurt R & Molvalilar S
P97 Transcriptional silencing of the IGF-I receptor inhibits proliferation of MCF-7 breast cancer cells
McVittie CJ, Ogunkolade W, Khalaf S, Bustin SA, Carpenter R & Jenkins PJ
P98 Diagnosis - 'query acromegaly'
Hordern SVM, Banu G & Nussey SS
P99 Factors determining remission of microprolactinomas after dopamine agonist withdrawal
Powrie JK & Athauda NB
P100 Pituitary tumor transforming gene (PTTG) regulates downstream angiogenic genes in thyroid cells
Kim DS, Boelaert K, Stratford AL, Eggo MC, Watkinson JC, Gittoes NJL, Franklyn JA & McCabe CJ
P101 Clinical studies of patients with neuroendocrine tumours (NETs)
Ali A, Richards D, Thakker RV & Hammersley MS
P102 IGF-I and IGFBP-3 mRNA expression in tamoxifen-resistant, recurrent breast cancers
McCarthy K, Laban CA, McVittie CJ, Ogunkolade WB, Khalaf S, Bustin SA, Carpenter R & Jenkins PJ
P103 IGF-I and IGFBP-3 mRNA expression in tamoxifen-resistant, recurrent breast cancers
McCarthy K, Laban CA, McVittie C, Ogunkolade WB, Khalaf S, Bustin SA, Carpenter R & Jenkins PJ
P104 A somatostatin analogue and octreotide exert anti-proliferative effects on colonic cancer cells
Khalaf S, Bailey F, Davies D, Ogunkolade BW, Kelly P, McCarthy K, Laban C, Bustin SA & Jenkins PJ
P105 Imbalance between separase and securin levels in thyroid and other malignancies
Khanim FL, Parmley JL, Boelaert K, Stratford AL, Manners A, Hodges N, McCabe CJ, Gittoes NJL & Franklyn JA
P106 The effects of ghrelin on IGF-I expression in normal and malignant breast tissue explants
Laban CA, Edwards C, Seb Gupta P, McCarthy K, Ogunkolade BW, Bustin SA, Edwards R, Carpenter R & Jenkins PJ
P107 Prevalence of hypopituitarism in patients with prolactin-secreting pituitary microadenomas
Behan LA, Seoighe D, Agha A, Sherlock M, Ryan J, Rogers B & Thompson CJ
P108 Systematic dose extension of octreotide LAR - the importance of individual tailoring of treatment
Thornton-Jones VA, Wass JAH & Turner HE
P109 Investigation into the efficacy of routine octreotide scanning in post-operative acromegalics with refractory disease
Creely SJ, Varma TR & Vora J
P110 Octreotide dependency: a cautionary tale
Levy MJ & Goadsby PJ
P111 Expression of SSTR subtypes (1-5) in normal and malignant colonic tissue
Ogunkolade BW, Kelly PD, Fairclough PD, Khalaf S, Bustin SA & Jenkins PJ
P112 Metastatic glucagonoma de-differentiated to an insulinoma: response to embolization
Dhillo WS, Meeran K & Todd JF
P113 Long acting somatostatin analogues administered by practice nurses: an audit
Fazal-Sanderson V, Thornton-Jones VA, Wass JAH & Turner HE
P114 Long-term remission following withdrawal of dopamine agonist therapy in subjects with microprolactinomas
Biswas M, Smith J, Jadon D, McEwan P, Rees DA, Evans LM, Scanlon MF & Davies JS
P115 The effects of pituitary tumours on cognitive function
Treece KA, Wass JA, Lincoln NB & Page RCL
P116 Novel actions of the anti-estrogen faslodex at the estrogen receptor
Fleming FJ, Hill AD, McDermott EW, O'Higgins NJ & Young LS
P117 Managing prolactinomas: our experience at Preston
Banerjee M, Myers M & Vice PA
P118 Expression and localisation of BAD and Akt in human breast cancer cell lines pre- and post- irradiation
Al-Bazz Y, Corke KP, Dobson PRM, Underwood JCE & Brown BL
P119 Bilateral laparoscopic adrenalectomy for ACTH-dependent Cushing's syndrome
Newell-Price J, Gandhi A & Harrison BJ
P120 BIM-23244, a somatostatin analogue with high affinity for somatostatin receptors 2 and 5, inhibits endothelial proliferation in vitro
Adams RL, Adams IP, Zhong W, Lindow SW  & Atkin SL
P121 Discrepancies between current consensus criteria for cure after transsphenoidal surgery for acromegaly
Petakov MS, Djurovic M, Miljic D, Doknic M, Pekic S, Popovic V & Damjanovic S
P122 Retrospective audit of bilateral adrenalectomies with reference to the occurrence of Nelson's syndrome
Green AJ, Barakat MT, Lynn JA & Meeran K
P123 Parathyroid imaging: which modality best informs surgical treatment?
Shaafi KO, West TET & Walsh T
P124 The efficacy of an octreotide test dose to predict the outcome of treatment for acromegaly with somatostatin LAR
Claridge AG, Shakoor SKA & Trainer PJ
P125 The changing patterns of presentation and treatment of acromegaly in the UK as reflected by the UK National Acromegaly Database
Wass JAH, Carson MN & Bates PR
P126 Improved quality of life (QOL) with normalisation of IGF-I in patients with acromegaly
Paisley AN, Rowles SV, Roberts ME, Lee C & Trainer PJ
P127 24-Hour ambulatory blood pressure monitoring (ABPM) in patients with acromegaly and the value of clinic blood pressure measurements
Paisley AN, Roberts ME, Heagerty AM & Trainer PJ
P128 Regional variations in colonic neoplasia in acromegaly
Ahmad B, Fazal-Sanderson V, Jewell DP, Warren B, Turner HE & Wass JAH
Growth and development
P129 The effect of nutritional deprivation in late gestation on uncoupling protein-2 mRNA abundance in the ovine neonatal lung
Gnanalingham MG, Mostyn A, Symonds ME & Stephenson TJ
P130 Possible factors determining individual sensitivity to GH replacement therapy; a KIMS database analysis
Monson J, Lundberg M, Bouloux PMG, Bevan JS, Svensson J, Koltowska-Häggström M & Finer N
P131 Do prolonged courses of testosterone affect final height in extreme maturational delay?
Lee R & Butler G
P132 The hydration fraction of lean body mass (LBM) does not change during six months physiological GH replacement in adults with severe GHD
Mukherjee A, Adams JE, Smethurst L & Shalet SM
P133 The relationship between maternal thyroid status in the antenatal period and new born growth measurements: a cohort study
Hindmarsh P, Franklyn JA, Clark P, Geary M, Rodeck C & Kilby MD
P134 Quality of life (QOL) improvement, during physiological GH replacement in severely GHD adults, is not explained by favourable changes in body composition
Mukherjee A, Adams JE, Smethurst L & Shalet SM
P135 Leptin and leptin receptor localisation in endocrine glands of fetal sheep
O'Connor DM, Wooding FBP, Hoggard N, Forhead AJ & Fowden AL
P136 The value of the TRH test in the assessment of hypothalamic-pituitary disorders in children
Tatnall S, Slim B, Kumar K, Patel L, Hall CM, Price DA & Clayton PE
P137 Frequency of single nucleotide polymorphisms in the GHRH receptor gene in short children
Smith KG, Gueorguiev M, Adams EF, Mein CA, Johnston LB, Bonner SE, Froguel P, Savage MO, Grossman AB & Korbonits M
P138 A dominant negative thyroid hormone receptor (TR) beta1 mutant enhances N-Tera-2 (NT2) cell proliferation
Chan SY, McCabe CJ, Franklyn JA & Kilby MD
P139 Transdermal testosterone application: pharmacokinetics and effects on pubertal status, short-term growth and bone turnover
Ahmed SF, Mayo A, MacIntyre H & Wallace AM
P140 Long-term association of the Y chromosome and blood pressure in boys at the pre- and post-pubertal periods
Charchar FJ, Shankar R, Eckert GJ, Tomaszewski M, Dominiczak AF & Pratt JH
P141 Growth hormone replacement reduces circulating inflammatory markers, blood pressure and large artery compliance but does not affect resistance artery function in adult hypopituitary patients
McCallum RW, Spiers A, Sattar N, Petrie JR, Dominiczak AF & Connell JMC
P142 Regulation of the growth hormone (GH) and insulin-like growth factor-I (IGF-I) paracrine pathway by thyroid hormone (T3) during bone development
Sriskantharajah S, O'Shea PJ, Yao H, Suzuki H, Cheng SY & Williams GR
P143 Pregnancy-induced plasticity in rat pituitary: a morphological and endocrine study of somatotroph and lactotroph function
El-Kasti MM, Christian HC, Huerta I, Hill N, Matthews DR & Wells T
P144 Gene expression in peripheral blood mononuclear cells: the effect of GH in a GH-deficient child
Whatmore AJ, Hayes A, Patel L & Clayton PE
Neuroendocrinology and behaviour
P145 The insulin tolerance test (ITT) in clinical practice: the experience of a busy pituitary unit
Liew A, Agha A, Finucane F, Thornton E, Rogers B, Tormey W & Thompson CJ
P146 Cardiovascular risk burden in adult patients with hypopituitarism
Kyaw Tun T, Agha A, Muigai N, Al-Sahli W, Rogers B, Tormey W & Thompson CJ
P147 Incorporating social preferences in the measurement of QoL outcomes in growth hormone deficiency (GHD) in adults
Kind P & Koltowska-Häggström M
P148 Neuroendocrine abnormalities in the acute phase of traumatic brain injury
Rogers B, Agha A, Mylotte D, Tormey W, Phillips J & Thompson CJ
P149 Investigating the potential role of melanocortin receptor 5 in the rodent adrenal gland
Kosti O, Renshaw D, Harrold J, Cone R & Hinson J
P150 Quality of life deficit in hypopituitary adults with growth hormone deficiency (GHD): comparison of age-sex matched patient data and a UK population survey
Koltowska-Häggström M, Monson JP, Hennessy S, Mattsson A & Kind P
P151 Downward resetting of the osmotic threshold for thirst in patients with syndrome of inappropriate antidiuretic hormone
Smith D, Moore K, Tormey W, Baylis PH & Thompson CJ
P152 Nephrogenic diabetes insipidus in the mouse does not deplete vasopressin neurons or activate oxytocin neurons
Morris JF, Epton MJ & Jenkins D
P153 Comparison of anterior pituitary annexin 1 expression in male/female and old/young Long Evans and Brattleboro rats
Davies E, Christian HC, Buckingham JC & Morris JF
P154 Prevalence of hypopituitarism in survivors of traumatic brain injury
Agha A, Rogers B, Tormey W, Phillips J & Thompson CJ
P155 The effect of oestrogen replacement therapy (ORT) on growth hormone (GH) dose; KIMS database perspective
Mah PM, Ross RJM, Jönsson P, Feldt-Rasmussen U, Koltowska-Häggström M & Webster J
P156 Metastatic glucagonoma transforming to an insulinoma
Byard A, Rangan S, Dixon A, Kos K, Edavalath M, Buch HN & Singh BM
P157 Investigation of the hypothalamo-pituitary-adrenal axis in patients with irritable bowel syndrome
Baskol M, Gokce C, Yucesoy M & Kelestimur F
P158 DNA microarray analysis of NECA action in a pituitary folliculostellate cell line
Rees DA, Scanlon MF & Ham J
P159 Imaging of the pituitary is indicated in marginal hyperprolactinaemia (<1000 milliunits per litre) to detect microadenoma
Shore HCA, Karavitaki N, Turner HE & Wass JAH
P160 Effects of melatonin on catecholaminergic neurotransmitters in brain areas regulating food intake in the male rat
Canpolat S, Sandal S, Kutlu S, Aydin M, Yilmaz B & Kelestimur H
P161 The acute octreotide suppression test is useful in predicting long-term responses to depot somatostatin analogue injections in patients with active acromegaly
Botusan I, Karavitaki N, Radian S, Turner HE & Wass JAH
P162 Effects of melatonin on the regulation of leptin production in rat anterior pituitary cells
Kus I, Sarsilmaz M, Colakoglu N, Kukner A, Ozen OA, Yilmaz B & Kelestimur H
P163 Primary therapy with somatostatin analogues in acromegaly does not restore orderly GH secretion
Parkinson C, Darzy K, Peacey SR, Thorner MO, Veldhuis JD, Trainer PJ & Shalet SM
P164 Down-regulation of neurotrophin receptor expression limits the regenerative potential of injured CNS neurons
Brown ER, Berry M & Logan A
P165 Functional interactions between anosmin-1, heparan sulphate and urokinase-type plasminogen activator and the pathogenesis of X-linked Kallmann's Syndrome
Hu Y, Gonzalez-Martinez D & Bouloux P
P166 Are cortisol responses to psychological stress related to size at birth in humans?
Ward AMV, Moore VM, Steptoe A, Robinson JS & Phillips DIW
P167 Addition of dopamine agonists to somatostatin analogue therapy improves biochemical control of acromegaly
Selverajah D, Webster J, Ross RJM & Newell-Price J
P168 Variability in GH assays undermines the value of consensus criteria for the diagnosis of adult GH deficiency and acromegaly
Pokrajac-Simeunovic A, Wieringa GE, Ellis AK & Trainer PJ
P169 The role of the melanocortin 5 receptor in the hypothalamic regulation of appetite and pituitary function
Sajedi A, Abbott CR, Small CJ, Haskell-Luevano C, Ghatei MA & Bloom SR
Reproduction
P170 Leptin, inhibin B and LH levels in patients with anorexia nervosa
Djurovic M, Pekic S, Cetkovic A, Doknic M, Petakov M, Damjanovic S, Zivkovic V, Dieguez C, Casanueva F & Popovic V
P171 Regulation of ovine placentome morphology by cortisol in late gestation
Ward JW & Fowden AL
P172 The effect of insulin-like growth factor I (IGF-I) on initiation of follicle growth in normal and polycystic ovaries in vitro
Stubbs S, Zachery-Jennings C, Margara R, Trew GH, Lavery S, Stark J, Hardy K & Franks S
P173 Specificity and clinical utility of methods for the detection of macroprolactin
Smith TP, Gibney J, Kavanagh L, Fahie-Wilson MN & McKenna TJ
P174 New approach in treatment of hyperandrogenism with triiodothyronine
Kazanavicius G
P175 Effect of supplementing the maternal diet with excess energy during late gestation on body fat deposition, reproductive performance and plasma insulin concentration in pigs
Laws J, Perkins KS, Litten JC, Corson AM & Clarke L
P176 The effects of thyroid hormone on cytokine-induced proliferation in human trophoblast cells
Barber KJ, Khanim FL, McCabe CJ, Bulmer JN, Whitley GS, Franklyn JA & Kilby MD
P177 Oral tibolone combined with testosterone as a potential male contraceptive: pharmacodynamic study examining additive effects in suppression of pituitary-testicular axis
Oxynos C & Wu FCW
P178 Routine screening for macroprolactin
Gibney J, Smith TP & McKenna TJ
P179 Microarray studies of human ovarian surface epithelium exposed to an inflammatory stimulus
Rae MT, Ross A, Niven D, Critchley HOD, Ghazal P, Lathe R & Hillier SG
P180 Peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists increase glucose metabolism in a human granulosa cell line (HGL-5)
Berdiaki A, Chatterjee VKK, Rainey WE & Franks S
P181 The CAM technique and follicle development
Qureshi AI, Bano G, Whitehead S, Nussey SS & Mason HD
P182 Paint thinner exposure inhibits testosterone synthesis and secretion in a reversible manner in the rat
Yilmaz B, Akpolat N, Canpolat S, Sandal S, Kutlu S, Ilhan N & Kelestimur H
P183 Ultrastructural and immunohistochemical examination of effects of leptin on testis in mice
Kus I, Canpolat S, Akpolat N, Ozogul C, Yilmaz B, Sarsilmaz M & Kelestimur H
P184 Stimulatory effects of ghrelin on spontaneous contractions in the rat myometrium
Kutlu S, Dayangac A, Ozcan M, Konar V, Kumru S & Ayar A
P185 The expression of somatostatin receptors in human granulosa cells
Adams IP, Staunton B, Gilson J, Adams RL, Robinson J & Atkin SL
P186 Anti-Müllerian hormone (AMH) protein expression in normal and polycystic human ovaries
Stubbs S, Webber L, Flanagan A, Da Silva-Buttkus P, Themmen APN, Visser JA, Groome NP, Hardy K & Franks S
P187 Effects of oral nomegestrol acetate, a 19 norprogesterone-derived progestin on the reproductive axis and lipids in men
Hay CJ & Wu FCW
P188 Follow up of women with Turner's syndrome in an adult endocrine clinic
Ghosh S, Hussein NM, Gibson C, Ray DW, Wu FC & Davis JRE
P189 TGFbeta signaling pathways in LHRH neurons
Galbiati M, Saredi S & Melcangi RC
P190 Müllerian inhibiting substance is elevated in obese women with PCOS and is suppressed by metformin treatment
Fleming R, Harborne L, MacLaughlin DT, Ling D, Norman J, Sattar N & Seifer DB
P191 Protein kinase (PKA)-independent but cAMP-dependent regulation of progesterone secretion by luteinizing human granulosa cells
Chin EC & Abayasekara DRE
P192 Intramuscular testosterone (T) undecanaote for the treatment of male hypogonadism: a parallel-group randomised open-label pharmacokinetic study
Hay CJ & Wu FCW
P193 Neurokinin B-like immunoreactivity can be detected in peripheral tissues in the non-pregnant rat
Brayley KJ & Bell NJ
P194 Biochemical evidence for follicular maturation (1): changes of inhibins and activin-A levels in follicular fluid from matched follicles
Wen XU, Tozer A, Butler SA & Iles RK
P195 Analysis of hCG beta core fragment glycosylation in normal and aberrant pregnancy by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry
Malatos S, Jacoby ES, Juneja NA, Butler SA, Kicman AT & Iles RK