| Monday 22 March |
| Sandoz Biopharmaceuticals Satellite Symposium |
| 09.00-10.00 |
De Vere Grand Hotel |
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Turner's syndrome: dilemma of the generations |
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| COFFEE |
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| 10.00-10.30 |
Main Foyer and Hewison Hall |
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| Symposium 1: Endocrinology of obesity |
| GENEROUSLY SUPPORTED BY ASTRAZENECA PLC |
| 10.30-12.30 |
Main Hall Chair: TBC |
| S6 |
10.30 |
Learning from experiments of nature
Farooqi S (Cambridge) |
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| S7 |
11.00 |
Uncovering the genetic causes of common obesity
Froguel P (London) |
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| S8 |
11.30 |
Gut feeling
Bloom SR (London) |
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| S9 |
12.00 |
Current approaches, future therapies
Finer N (Cambridge) |
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| Clinical Management Workshop 1: Electrolyte disturbances |
| 10.30-12.30 |
Alpha Room Chair: PH Baylis (Newcastle) |
| S35 |
10.30 |
Cerebral salt wasting
Thompson CJ (Dublin) |
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| S36 |
11.10 |
Unexplained hyponatraemia - diagnosis strategies
Verbalis JG (Washington, DC, USA) |
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| S37 |
11.50 |
Potassium homeostasis: the renal perspective
Unwin R (London) |
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| Oral Communications 1: Reproduction |
| 10.30-12.30 |
Beta Room Chairs: S Franks (London) & R Abayasekara (London) |
| OC1 |
10.30 |
Allopregnanolone is involved in reduced HPA axis responses to immune challenge in late
pregnancy
Brunton PJ, Harrison CEL & Russell JA |
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| OC2 |
10.45 |
Gonadotrophs in annexin 1 knockout mice demonstrate enhanced secretory
activity by structural analysis
Wain S, Morris JF, Buckingham JC & Christian HC |
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| OC3 |
11.00 |
Decidual activation of vitamin D3 - a novel immunomodulatory mechanism in early
gestation
Evans KN, Innes BA, Bulmer JN, Kilby MD & Hewison M |
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| OC4 |
11.15 |
An anti-inflammatory role for progesterone at the human ovarian surface?
Niven D, Rae MT, Critchley HOD & Hillier SG |
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| OC5 |
11.30 |
Orlistat and metformin are equally beneficial in reducing hyperandrogenaemia
in polycystic ovarian syndrome
Jayagopal V, Kilpatrick ES, Holding S, Jennings PE & Atkin SA |
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| OC6 |
11.45 |
Effect of a high n-6 polyunsaturated fatty acid (PUFA) diet on COX expression
and PGE2 synthesis in the ovine amnion during gestation
Kirkup SE, Cheng Z, Chin E, Elmes M, Wathes DC & Abayasekara DRE |
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| OC7 |
12.00 |
Placental endokinins may play a paracrine role on the placental vasculature
Page NM, Gardiner SM, Morrish DW, Manyonda IT & Lowry PJ |
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| OC8 |
12.15 |
Effect of maternal dexamethasone treatment on hepatic and renal type
I 5'-monodeiodinase activity and plasma triiodothyronine concentration
in fetal sheep |
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Forhead AJ, Giussani DA & Fowden AL |
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| LUNCH |
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| 12.30-13.15 |
Main Foyer and Hewison Hall |
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| Nurses Workshop with Lunch: Compiling a portfolio |
| GENEROUSLY SUPPORTED BY SERONO LTD |
| 12.30-13.15 |
Beta Room |
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| Symposium 2: Actions of insulin in non-classical target tissues |
| 13.15-15.15 |
Main Hall Chair: PM Jones (London) |
| S10 |
13.15 |
Insulin signalling through PI 3-kinase
Cohen P (Dundee) |
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| S11 |
13.45 |
Insulin regulation of pancreatic beta cells
Withers D (London) |
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| S12 |
14.15 |
Insulin effects on cell signalling and nitric oxide synthesis in vascular endothelium
Mann GE (London) |
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| S13 |
14.45 |
Insulin action in the ovary
Franks S (London) |
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| Oral Communications 2: Development and growth |
| 13.15- |
15.15 |
Alpha Room Chairs: A Logan (Birmingham) & JMP Holly (Bristol) |
| OC9 |
13.15 |
The expression of monocarboxylate transporter 8 as a specific thyroid
hormone transporter in human fetal brain and placenta: the effects of intrauterine
growth restriction (IUGR) |
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Chan SY, McCabe CJ, Boelaert K, Visser TJ, Friesema EC, Franklyn JA & Kilby MD |
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| OC10 |
13.30 |
Key mitotic regulators securin and separase in the human fetal brain |
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Boelaert K, Pemberton HN, Kim DS, Tannahill LA, Chan SY, Khanim FL,
Gittoes NJ, Franklyn JA, Kilby MD & McCabe CJ |
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| OC11 |
13.45 |
KAL-1 and KAL-2 ontogeny and in vitro function in human GnRH-1 developing
system |
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Gonzalez-Martinez D, Hu Y, Schofield J, Kim S & Bouloux P |
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NOVARTIS AWARD WINNER (NP1) ALSO PRESENTED IN A DEDICATED POSTER SESSION IN HEWISON
HALL ON TUESDAY 23 MARCH AT 12.30. |
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| OC12 |
14.00 |
Alterations of the somatotrophic axis in the obese agouti (Ay/a) mouse
Martin NM, Houston PA, Patterson M, Carmignac DF, Ghatei MA, Bloom SR & Small
CJ |
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| OC13 |
14.15 |
A novel GH variant (Ile179Met) exhibits a decreased ability to activate the ERK
pathway
Lewis MD, Horan MP, Millar DS, Easter TE, Fryklund L, Gregory JW, del
Valle CJ, Canete R, Ulied A, Procter AM, Cooper DN & Scanlon
MF |
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| OC14 |
14.30 |
The susceptibility of growth hormone missense variants to proteolytic degradation |
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Easter TE, Millar DS, Horan MP, Newsway V, Fryklund L, Procter AM,
Cooper DN, Scanlon MF & Lewis MD |
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| OC15 |
14.45 |
Internalization of the GH antagonist pegvisomant |
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Maamra M, Kopchick JJ, Strasburger CJ & Ross RJM |
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| OC16 |
15.00 |
Responsiveness to growth hormone (GH) is increased in obesity |
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Gleeson HK, Lissett CA & Shalet SM |
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| Nurses Session: Congenital adrenal hyperplasia |
| 13.15-15.15 |
Beta Room Chair: S King (London) & E McGregor (Birmingham) |
| S44 |
13.15 |
Congenital adrenal hyperplasia: a multi-system disorder
Hughes IA (Cambridge) |
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| S45 |
14.00 |
Assessing the need for an interpreter in families of children with CAH from an ethnic
background
Jones JA (Manchester), Das U, Bucko J, Clayton PE & Hall CM |
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| S46 |
14.30 |
Congenital adrenal hyperplasia: the nurses' perspective
Ward ST (London) |
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14.45 |
Case presentations: |
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63 years, 10 consultants, one woman; a patients perspective of CAH
Miller M (Newcastle) |
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Siblings with CAH; ben there, done that, got the t-shirt
Barstow D (Newcastle) |
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| TEA |
| 15.15-15.45 |
Main Foyer and Hewison Hall |
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| Nurses Tea |
| GENEROUSLY SUPPORTED BY SERONO LTD |
| 15.15-15.45 |
The Brighton Centre Suite 3 |
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| Symposium 3: Pituitary adenomas |
| 15.45-17.15 |
Main Hall Chair: J Newell-Price (London) |
| S14 |
15.45 |
Somatostatin and dopamine receptors in vitro
Hafland L (Rotterdam, The Netherlands) |
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| S15 |
16.15 |
Natural history of prolactinomas: lessons after withdrawal of long-term cabergoline
Colao A (Naples, Italy) |
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| S16 |
16.45 |
Clinical markers of aggressive behaviour in non-functioning pituitary adenomas
Turner HE (Oxford) |
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| Oral Communications 3: Thyroid |
| 15.45-17.15 |
Alpha Room Chairs: JH Lazarus (Cardiff) & MC Eggo (Birmingham) |
| OC17 |
15.45 |
Thyroid hormone (T3) activates fibroblast growth factor (FGF) receptor signalling in
bone
Barnard JC, Williams AJ, Harvey CB & Williams GR |
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| OC18 |
16.00 |
Biological consequences of gain-of-function thyrotropin receptor (TSHR)
mutant expression in adipose tissue
Baker GRC, Gregory JW, Bakhsh A, Betts PR, Hughes IA & Ludgate M |
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| OC19 |
16.15 |
PBF predicts recurrence in thyroid cancer and potentiates the actions of PTTG in
vitro
Stratford AL, Boelaert K, Franklyn JA & McCabe CJ |
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| OC20 |
16.30 |
Steroid modulation of peripheral cytokine expression: increased resistance
to dexamethasone and progesterone inhibition of type 1 CD4+ response in
autoimmune thyroiditis
Okosieme OE, Premawardhana LDKE, Parkes AB & Lazarus JH |
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| OC21 |
16.45 |
Gender, age, goitre type and serum TSH level predict thyroid neoplasia
in 1500 patients with thyroid enlargement investigated by FNAC
Boelaert K, Horacek Y, Daykin J, Sheppard MC & Franklyn JA |
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| OC22 |
17.00 |
Defining genetic predictors for the development of Graves' disease in young females
Collins JE, Heward JM, Cordell H, Franklyn JA & Gough SCL |
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| Symposium 4: The extracellular calcium-sensing receptor in endocrine
tissues |
| 15.45-17.15 |
Beta Room Chair: P Squires (Coventry) |
| S17 |
15.45 |
The calcium-sensing receptor and disorders of calcium-sensing
Brown EM (Boston, MA, USA), Kifor O, Yano S, Butters R & Chattopadhyay
N |
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| S19 |
16.15 |
Calcium sensing and bone development
Bland R (Coventry) |
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| S18 |
16.45 |
Extracellular calcium as direct modulator of bone function
Riccardi D (Manchester), Dvorak MM, Siddiqua A, Carter DH & Dallas
SL |
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| Society for Endocrinology Transatlantic Medal Lecture |
| 17.30-18.15 |
Main Hall Chair: SR Bloom (London) |
| S1 |
17.30 |
Adipose tissue as an endocrine organ
Flier J (Boston, MA, USA) |
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| Welcome Reception |
| GENEROUSLY SUPPORTED BY BRIGHTON & HOVE CITY COUNCIL |
| 18.30-19.15 |
Main Foyer and Hewison Hall |
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| Champagne and Chips |
| GENEROUSLY SUPPORTED BY PFIZER LTD |
| 20.00 |
Brighton Pier (entrance by ticket only) |
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