Programme

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Monday 7 April
 09.00 onwards     Registration
Main Foyer
     
 10.30 12.30    Bone and Mineral Special Interest Group Satellite: Osteoporosis
In association with the National Osteoporosis Society
Generously supported by Novartis & Roche
Queen's Suite 2
Chairs: J Wass (Oxford) & R Eastell (Sheffield)
10.30 Reception
11.00 Chairman's introduction: osteoporosis - the silent epidemic?
J Wass (Oxford) & R Eastell (Sheffield)
11.10 NICE ways to manage osteoporosis
P Selby (Manchester)
11.30 'But doctor I can't take generic alendronic acid!'
R Eastell (Sheffield)
11.50 'But doctor no guidelines apply to my situation'
S Orme (Leeds)
12.10 So you want to set up an osteoporosis service?
A McLellan (Glasgow)
     
 10.30 12.30    Andrology Special Interest Group Satellite: Controversies in the diagnosis and management of hypogonadism
Generously supported by Bayer Schering Pharma & ProStrakan
Queen's Suite 1
Chair: H Jones (Sheffield)
10.30 Hypogonadism and diabetes
H Jones (Sheffield)
10.50 Aging, frailty and testosterone
F Wu (Manchester)
11.10 Difficulties in the diagnosis of hypogonadism
S Arver (Stockholm, Sweden)
11.30 Testosterone and prostate safety
M Feneley (London)
11.50 Discussion
     
 12.30 13.00    Lunch
Hall Q
     
 13:00 15:00     Symposium 1: New twists in appetite/satiety signalling pathways
King's Suite
Chairs: S O'Rahilly (Cambridge) & K Smith (London)
13.00 S9 Plasma triglycerides and appetite control
W Banks (St Louis, USA)
13.30 S10 Imaging the brain appetite network
S Luckman (Manchester)
14.00 S11 Role of central serotonin 2C receptors in appetite control
L Heisler (Cambridge)
14.30 S12 Central role of AMP-Kinase in appetite control
M Korbonits (London)
     
 13:00 15:00    Clinical Management Workshop 1: Fibrous dysplasia and McCune-Albright syndrome
Supported by Clinical Endocrinology
Main Auditorium
Chairs: R Thakker (Oxford) & M Cooper (Birmingham)
13.00 S44 The endocrine consequences of McCune-Albright syndrome
P Trainer (Manchester)
13.40 S45 Molecular genetics and cell biology of McCune-Albright syndrome and fibrous dysplasia
L Weinstein (Bethesda, USA)
14.20 S46 Medical treatment of fibrous dysplasia of bone
R Chapurlat (Lyon, France)
     
 13:00 15:00    Molecular Endocrinology Workshop
Queen's Suite 1
Chairs: M Gurnell (Cambridge) & K Boelaert (Birmingham)
13.00 S70 Cell metabolomics: differential metabolism of glucose and fructose in pancreatic cancer
T Heaney (Los Angeles, USA)
14.00 S71 Combining mouse genetics, transgenics and knockouts to explore the biology of MC1R aganism and antagonism
I Jackson (Edinburgh)
     
 15:00 15:30    Coffee
Hall Q
     
 15:30 17:30    Symposium 2: System-specific effect steroids
King's Suite
Chairs: S Lightman (Bristol) & G Lavery (Birmingham)
15.30 S13 Glucocorticoid signalling in the brain
S Lightman (Bristol)
16.00 S14 Glucocorticoids, 11beta HSDs and neuroprotection
M Holmes (Edinburgh)
16.30 S15 Glucocorticoids, liver, fat and metabolic syndrome
P Stewart (Birmngham)
17.00 S16 Glucocorticoids, folliculo-stellate cells and the pituitary
H Christian (Oxford)
     
 15:30 17:30    Oral Communications 1: Young Endocrinologists Prize Session
Main Auditorium
Chairs: J Wass (Oxford) & A McNeilly (Edinburgh)
15.30 OC1 Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B gene mutation carriers
U Srirangalingam; L Walker; B Khoo; F MacDonald; D Gardner; T Wilkin; R Skelly; E George; D Spooner; J Monson; A Grossman; S Akker; P Pollard; N Plowman; N Avril; D Berney; J Burrin; R Reznek; V Kumar; E Maher; S Chew;
15.45 OC2 The ghrelin-cannabinoid axis – a novel pathway in the regulation of appetite and metabolism
F Amin; B Kola; M Christ-Crain; F Lolli; G Wittmann; J Harvey-White; G Kunos; A Grossman; C Fekete; M Korbonits;
16.00 OC3 Does 11beta-HSD1 in visceral adipose tissue (VAT) deliver cortisol to the liver? Studies with portal vein sampling and tracer infusion in humans.
R Stimson; R Andrew; D Redhead; P Hayes; B Walker;
16.15 OC4 Hypoxia and GC signalling regulate macrophage migration inhibitory factor (MIF) gene expression through a common element
L Elsby; R Donn; Z Alourfi; E Beaulieu; D Ray;
16.30 OC5 Placental vascular development and nutrient transport in 11ß-HSD2-/-mice
C Wyrwoll; J Seckl; M Holmes;
16.45 OC6 MRAP2 permits the functional expression of the melanocortin-2-receptor: a new member of a new family of melanocortin receptor accessory proteins
L Chan; L Metherell; M Elphick; J Chapple; A Clark;
17.00 OC7 Testosterone treatment improves muscle strength, lean mass and quality of life in prefrail and frail elderly men: Results from a randomised double-blind placebo-controlled study
U Srinivas-Shankar; S Roberts; J Adams; M Connolly; J Oldham; F Wu;
17.15 OC8 β-cell 11β-Hydroxysteroid dehydrogenase type 1 contributes to Type 2 Diabetes.
S Turban; L Ramage; J Paterson; J Mullins; J Seckl; N Morton;
     
 15:30 17:30    Oral Communications 2: Reproduction
Queen's Suite 1
Chairs: H Critchley (Edinburgh) & J Prague (London)
15.30 OC9 Dynamic responses of oestrogen receptors revealed by fluorescent recovery after photobleaching (FRAP)
C Fitzgerald; F Collins; P Brown; V Bombail; K Kerr; S Macpherson; M Millar; P Saunders;
15.45 OC10 Expression of somatostatin receptors 1-5 in normal human endometrium through the menstrual cycle
E Dickerson; K Bedford; I Richmond; S Maguiness; J Robinson; S Xu; S Atkin;
16.00 OC11 Identification of a novel compound heterozygous mutation in the gonadotrophin releasing hormone receptor in two siblings with isolated hypogonadotrophic hypogonadism
A Chesover; S Kim; J Ahlquist; P Bouloux;
16.15 OC12 Modelling Kallmann's Syndrome in the zebrafish
S Cadman; G Philp; S Kim; P Bouloux; I Mason;
16.30 OC13 Effect of hypoxia and inflammatory and anti-inflammatory signals on gene expression in sheep ovarian surface epithelium (OSE) in vitro.
C Harlow; M Rae; D Price; A McNeilly; S Rhind; S Hillier;
16.45 OC14 IGF-mediated cell turnover in the human placenta is positively regulated by the protein tyrosine phosphatase, SHP-2.
K Forbes; J Aplin; M Westwood;
17.00 OC15 Evaluation of the prevalence of vitamin D deficiency and its treatment in a west London pregnant population
H Salmasi; A Banerjee; M Donaldson; A Wren;
17.15 OC16 Enhanced hypothalamic-pituitary-adrenal axis activation, 5α-reductase activity and insulin resistance distinguishes polycystic ovary syndrome from simple obesity
D Vassiliadi; J Tomlinson; B Hughes; C Gay; S Sira; P Nightingale; C Shackleton; P Stewart; W Arlt;
     
 17:30 17:45    Tea
Hall Q
     
 17:45 18:45    Young Endocrinologist Prize Lectures
Main Auditorium
Chairs: P Stewart (Birmingham) & A McNeilly (Edinburgh)
17.45 S64 Peptide YY: Food for thought
R Batterham (London)
18.15 S65 11b-HSD1 and metabolic disease: a mouses’ Tail
N Morton (Edinburgh)
     
 18:45 onwards     Welcome Reception
Holiday Inn
     
 19:45 onwards     Young endocrinologists quiz night
Generously supported by Fisher Scientific & Novo Nordisk Ltd
Hall D