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CodeAbstractAuthorsCategory
P1 Hypercalcaemia following a Road Traffic Accident. Nyi Htwe, Koshy JacobBone
P2 Protracted Hungry Bone Syndrome Post Parathyroidectomy for Primary Hyperparathyroidism Subhash Rana, Vijay Bangar, Khaled Al-Zwae, Abdusalam MousaBone
P3 Hypertrophic Pulmonary Osteoarthropathy: not all longstanding raised Bony Alkaline Phosphatase is Paget’s Disease Ahmed El-Laboudi, Emma WardBone
P4 Vitamin D sufficiency is rare in patients attending the Endocrine Antenatal Clinic even in the Caucasian population. Ammar Tarik, Deepan Bathia, Emma WardBone
P5 A mouse model, Slip, for an X-linked metaphyseal chondrodysplasia Chris Esapa, Rosie Head, Simona Di Pretoro, Elisabeth Crane, Holly Evans, Gethin Thomas, Steve Brown, Roger Cox, Matt Brown, Peter Croucher, Rajesh ThakkerBone
P6 Bone Mineral Density in Transitional Endocrine Clinic in a UK Teaching Hospital Gayatri Sreemantula, Cherakkattil Iqbal, Mohammed Didi, Aftab AhmadBone
P7 Osteoporosis in a young cohort: aetiology and gender differences in referral for DXA Stephen Ryan, Rachel K Crowley, Shawn Chavrimootoo, Sinead Harney, Antoinette TuthillBone
P8 Vitamin D deficiency in primary hyperparathyroidism- prevalence and complications Vidhya Jahagirdar, Sundus Yahya, Andrew Bates, Asad RahimBone
P9 Osteoporosis in Patients with Chronic Obstructive Pulmonary Disease Mohammad Alhadj Ali, Said Hamdoun, Abdallah KhouryBone
P10 Recurrence of spontaneously resolving hypercalcaemia, an unusual case. nihad jaleel, darryl meeking, lorraine albon, lina chongBone
P11 Assessment of Vitamin D status in patients with primary hyperparathyroidism. Mary Jane Brassill, Muhammed Adrees, John O'Mullane, Antoinette TuthillBone
P12 Secondary Preventative Alendronate use in the Prevention of Fragility Fractures in women above 75 years: The Implementation of NICE Guidance Ramalingam Srinivasan, Mazhar Zaidi, Adam DevanyBone
P13 Is it time to replace the 24 hour urine calcium : creatinine clearance ratio in the investigation of PTH-dependent hypercalcaemia? Jaimini Cegla, Sharan Saroya, Barbara McGowan, Mandy Donaldson, Tricia TanBone
P14 Mutational analysis of the PHEX gene in three patients with X-linked hypophosphatemic rickets: discovery of a novel point mutation Tina Kienitz, Manfred Ventz, Elke Kaminsky, Marcus QuinklerBone
P15 A study on accuracy of Sestamibi and Ultrasound scanning in identifying a solitary parathyroid adenoma in patients with primary hyperparathyroidism SENTHILKUMAR KRISHNASAMY, RESHMI MANJUNATHA, SANJAY VYDIANATH, PETER STOUHAL, VARADARAJAN BASKAR, BALDEV M SINGH, HARIT BUCHBone
P16 A novel GATA3 mutation, Tyr345Cys, in Hypoparathyroidism, Deafness and Renal dysplasia (HDR) syndrome results in abolished DNA binding Irina Grigorieva, Katie Gaynor, Treena Cranston, Catherine McWilliam, Faisal Ahmed, M. Andrew Nesbit, Rajesh ThakkerBone
P17 Adenosine A2b receptors induce osteoblastogenesis whereas A1 receptors induce adipogenesis Borzo Gharibi, Jack Ham, Bronwen EvansBone
P18 Management of primary hyperparathyroidism- Are we following the guidelines? Abdul Rafi Mohammed, Joyce Cheung, Rustam ReaBone
P19 Hereditary renal calcification locus, Rcalc1, is associated with altered expression of cell survival genes Nellie Y. Loh, Michael J. Stechman, Herbert Schulz, Jeshmi Jeyabalan, Anita A.C. Reed, Bushra Ahmad, Michelle Stewart, Steve D.M. Brown, Norbert Huebner, Rajesh V. ThakkerBone
P20 Is Vitamin D deficiency a common cause of elevated PTH post-parathyroidectomy? Starla Yarde, Tony Skene, Joe Begley, Abigail Evans, Tristan RichardsonBone
P21 Transient receptor potential cation channel, subfamily Vanilloid, member 5 (Trpv5) mutation (Ser682Pro) results in loss of apical membrane expression in the distal convoluted tubule, thereby resulting in hypercalciuria Nellie Y. Loh, Henrik Dimke, Liz Bentley, Paolo Tammaro, Tertius Hough, Roger D. Cox, Steve D.M. Brown, Frances M. Ashcroft, Joost Hoenderop, René Bindels, Rajesh V. ThakkerBone
P22 AMP-activated protein kinase (AMPK) regulates in vitro bone formation and bone mass in vivo Mittal Shah, Attia Bataveljic, Benoit Violet, Tim Arnett, Leanne Saxon, Marta Korbonits, chantal ChenuBone
P23 A mouse model of early-onset renal failure, tertiary hyperparathyroidism and renal osteodystrophy Chris Esapa, Rosie Head, Simona Di Pretoro, Elisabeth Crane, Nellie Loh, Olivier Devuyst, Gethin Thomas, Steve Brown, Matt Brown, Peter Croucher, Roger Cox, Rajesh ThakkerBone
P24 The association among bone mineral density (BMD), 24-hour mean sex hormone binding globulin (SHBG) concentration and its circadian rhythm Aung Mon, Franklin Joseph, Anna Robinson, Ashwin Joshi, Nagaraj Malipatil, Rabia Aftab, William Fraser, Jiten VoraBone
P25 Extra-pituitary expression of the prolactin gene in the bone and cartilage of an hPRL-Luc transgenic rat model Sabrina Semprini, Judith R McNeilly, Lindsay Ramage, David G Brownstein, Donald M Salter, Alan McNeilly, Michael RH White, Julian RE Davis, John J MullinsBone
P26 PREVELANCE OF VARIOUS MORBIDITY IN NORTH INDIAN ADULT OBESE PATIENTS hemanta nayak, dinesh dhanwalClinical practice/governance and case reports
P27 Intervention to improve the management of diabetes in an academic primary care practice Assim AlfaddaClinical practice/governance and case reports
P28 Are adrenal incidentalomas routinely referred to endocrinology services ? - an audit of referral pattern and appropriate investigation. Louise Osborne, Steve R PeaceyClinical practice/governance and case reports
P29 Kelp Induced Thyrotoxicosis James Lawrence, Lina, Pui Lin ChongClinical practice/governance and case reports
P30 Unusual Presentation of a Phaeochromocytoma Sumudu Bujawansa, King Sun LeongClinical practice/governance and case reports
P31 Severe abdominal pain as presentation of Addison’s disease in undiagnosed case of autoimmune polyglandular disease. Bashir El-Mahmoudi, Tony Tetlow, Chaminda JayawarnaClinical practice/governance and case reports
P32 A CASE OF POLYGLANDULAR AUTOIMMUNE SYNDROME TYPE II AND SARCOIDOSIS Ghulam Mustafa Shaikh, Matthew MurphyClinical practice/governance and case reports
P33 The importance of HLA haplotype analysis in the Polyglandular Autoimmune Syndromes Allison Martin, Gul BanoClinical practice/governance and case reports
P34 Marked Hypercalcaemia In A Case Of Primary Hyperparathyroidism Devesh Sennik, Safdar Naqvi, Damodharan SureshClinical practice/governance and case reports
P35 “Mighty oaks from little acorns grow”: A review of the development of Endocrine Nursing in the UK. Maggie CarsonClinical practice/governance and case reports
P36 Altered Time-Effect Profile of Insulin Glargine in Overdose: A Case Report Zaki Hassan-Smith, Kalyan GangopadhyayClinical practice/governance and case reports
P37 The pitfalls of abrupt reduction in glucocorticoid availability – illustrated in the treatment of Cushing’s Syndrome Tolu Olateju, Micheal CummingsClinical practice/governance and case reports
P38 A case of microprolactinoma in a young man presenting as obesity despite regular heavy exercise. Sarah Bradley, Milan Piya, Shahrad TaheriClinical practice/governance and case reports
P39 Insulin Induced Hypoglycaemia in Hospital Inpatients Caryn Wujanto, Sophie Barlow, Paresh MistryClinical practice/governance and case reports
P40 Cushing’s disease or pituitary incidentaloma? Hemanth Bolusani, Srinivasa Munigoti, Neera Agarwal, Steve Davies, Aled ReesClinical practice/governance and case reports
P41 Extensive Hirsutism, a valuable clue to a sinister pathology Yared Demssie, Annice Mukherjee, Tara Kearney, Akheel A SyedClinical practice/governance and case reports
P42 Aetiology of Hyperprolactinaemia Sharon Sheehan, Thomas King, Sze Ann Woon, Ana Rakovac-Tisdall, John McDermott, Seamus SreenanClinical practice/governance and case reports
P43 Testosterone replacement in the setting of Finasteride therapy: a therapeutic dilemma Christian Hariman, Laks Varadhan, Adrian Walker, George VarugheseClinical practice/governance and case reports
P44 Addison's disease unmasking an occult systemic cause for cerebral ischaemic event. Christian Hariman, Laks Varadhan, Indira Natarajan, Adrian Walker, George VarugheseClinical practice/governance and case reports
P45 BARIATRIC SURGERY IN RENAL TRANSPLANT RECIPIENTS Salma S Kamaledeen, Marco Bueter, Ahmed Ahmed, Carel W Le RouxClinical practice/governance and case reports
P46 Intermittent galactorrhoea due to vacant episodes Sampath Satish Kumar, chinnadori RajeswaranClinical practice/governance and case reports
P47 Assessment of risk factors given in GP referral letters for DEXA imaging. Ghulam Mustafa shaikh, Mortimer.B O'Connor, Jeetandra Rathi, Fredo Lainis, Ursula Bond, Joan Swan, Matthew Murphy, Mark.J PhelanClinical practice/governance and case reports
P48 Forensic Endocrinology: A Case Report of Factitious Hypoglycaemia Yee Seun Cheah, Atim Etok, Andrew Gough, Pauline Kane, Simon Aylwin, Klaus-Martin Schulte, Jackie GilbertClinical practice/governance and case reports
P49 Severe hypoglycaemia leading to death in a patient with Type 2 diabetes – Insulinoma, sulphonylurea overdose or some other cause? Lina, Pui Lin Chong, Nihad Jaleel, Darryl MeekingClinical practice/governance and case reports
P50 Hypocalcaemia Post Total Thyroidectomy: A Clinical Experience RAHAT MAITLAND, JOHN MIELLClinical practice/governance and case reports
P51 Mass in the median eminence: an unusual cause of confusion Aikaterini Theodoraki, Pierre-Mark Bouloux, Bernard KhooClinical practice/governance and case reports
P52 A CASE OF FATAL ACUTE SEVERE MULTI-FACTORIAL HYPONATRAEMIA Agnieszka Falinska, Dina Saleh, Alex Comninos, Khalid AhmedClinical practice/governance and case reports
P53 An unusual presentation of polyendocrinopathy Maya Venu, Haris Marath, Francesca SwordsClinical practice/governance and case reports
P54 Acute fatty liver due to poor diabetic control. Agnieszka Swiecicka, Manjunath MaligeClinical practice/governance and case reports
P55 A Case of Pseudo-Carcinoid Craig Stiles, Manilka Sumanatilleke, Will DrakeClinical practice/governance and case reports
P56 Investigating for Cushing's syndrome in a patient with increased BMI on rifampicin Mansoor Ali, Julie Andrew, Wycliffe Mbagaya, Steve OrmeClinical practice/governance and case reports
P57 Granulomatous Infiltration of the Pituitary Gland Jackie Gilbert, Victor Oguntolu, Dulka Manawadu, Jon SalisburyClinical practice/governance and case reports
P58 Audit on the Safety of the Insulin Stress Tests in a Tertiary Endocrine Referral Centre: Jen Min Ng, Myint Aye, Leanne Ward, Deepa Narayanan, Stephen L Atkin, Eric S KilpatrickClinical practice/governance and case reports
P59 The use of Insulin Stress Test as an Assessment of Tiredness Srilatha Dampetla, Jen Ng, Deepa Narayanan, Eric Kilpatrick, Stephen AtkinClinical practice/governance and case reports
P60 A case of Hypomagnesemia Pradeep Karur, Godwin SimonClinical practice/governance and case reports
P61 Hyperandrogenism with an abdominal mass but an ovarian source Susan Knox, Colin PerryClinical practice/governance and case reports
P62 Diabetes insipidus secondary to caseating granulomatous disease Taimour Alam, Steven Thomas, Vijay BangarClinical practice/governance and case reports
P63 CASE OF POST MENOPAUSAL STEROID CELL OVARIAN TUMOR ANUPAM BRAHMA, MAYA VENU, T DUNCAN, C GEEVARGHESEClinical practice/governance and case reports
P64 A man with short stature and absent testis Prashant Singh, Pat Pickett, Adwin Rooproy, Probal Moulik, Andrew MacleodClinical practice/governance and case reports
P65 A rare case of isolated Cushing’s disease from an ACTH and growth hormone staining pituitary adenoma Rupa Ahluwalia, Jiten VoraClinical practice/governance and case reports
P66 What a difference a dose makes! Unexpected test results lead to improved communication. Katherine Powell, Sondra Gorick, Mike SampsonClinical practice/governance and case reports
P67 Hypercalcaemia due to PTH-related peptide secretion by small cell carcinoma of the ovary. Katherine Simpson, George Tharakan, Andy Coady, Malcolm Padwick, Michael ClementsClinical practice/governance and case reports
P68 Low Sodium and Neurological Findings: Consider the Diagnosis. Mary Jane Brassill, Antoinette TuthillClinical practice/governance and case reports
P69 Androgen-producing tumour in a transposed ovary: A diagnostic difficulty Wasala M H S Chandrasekara, Saravanan Balaguruswamy, Sid McNulty, Niall FurlongClinical practice/governance and case reports
P70 Insulin Autoimmune Syndrome - A rare case of hypoglycaemia. Suma Sugunendran, Mohamed MalikClinical practice/governance and case reports
P71 Improving Patient Awareness of Antithyroid Medications Lina, Pui Lin Chong, James LawrenceClinical practice/governance and case reports
P72 A case of hypogonadotrophic hypogonadism due a pituitary stalk tuberculoma Amalia Iliopoulou, Joachim Stolte, Dinesh NagiClinical practice/governance and case reports
P73 Recurrent Pituitary Apoplexy Binu Krishnan, Vooi Loh, Gul BanoClinical practice/governance and case reports
P74 A Case of Connective Tissue Disease Complicated by Multiple Metabolic Disorders Milan Piya, Abd Tahrani, Philip Dyer, Jayadave Shakher, Alan JonesClinical practice/governance and case reports
P75 The dangers of drinking liquorice tea James Lawrence, Lina, Pui Lin ChongClinical practice/governance and case reports
P76 A Case of Functional Parathyroid Adenoma Fahad Wali Ahmed, Trevor Wheatley, Mehrdad Khonsari, Charles ZammitClinical practice/governance and case reports
P77 A rare cause of a common problem Rhodri King, Sam Khan, C Rajeswaran, Mark FreemanClinical practice/governance and case reports
P78 Chronic Lymphocytic Infundibulitis With Visual Field Defects, Partial Hypopituitarism and Diabetes Insipidus. Rachel Polock, Katherine Davies, Catrin Barwick, Edward Favill, Avril Wayte, Anthony WiltonClinical practice/governance and case reports
P79 Misdiagnosed Adrenal Carcinoma With Recurrence of Cushing’s Syndrome Complicated By Spontaneous Hypoglycaemia. Samuel Parker, Heledd Roberts, Sarah Wenham, Avril Wayte, Anthony WiltonClinical practice/governance and case reports
P80 Successful treatment of severe Premenstrual dysphoria by a GnRH analogue and hormone add-back Trevor Wheatley, Fahad Wali AhmedClinical practice/governance and case reports
P81 Hypertension in Familial Adenomatous Polyposis (FAP) – Don’t be Conn’d! Tom Hopkins, Tricia Tan, Victoria Salem, Fausto Palazzo, Kareem MeeranClinical practice/governance and case reports
P81.1 Pituitary apoplexy in cushings disease Surya Rajeev, Stephen StanawayClinical practice/governance and case reports
P82 Audit of hypothyroid management in pregnancy Surya Rajeev, Rebecca Jones, Helen WhiteClinical practice/governance and case reports
P83 Severe hypomagnesaemia associated with proton pump inhibitor therapy Sanjaya Dissanayake, Simon Howell, Simon Wallis, Kalpana KaushalClinical practice/governance and case reports
P84 Recurrent pregnancy-related hypokalaemia associated with Gitelman’s syndrome Saravanan Balaguruswamy, WMHS Chandrasekara, Sandhya Rao, Niall Furlong, Tarig AbdallaClinical practice/governance and case reports
P85 An unusual cause of hyperparathyroidism Tanya Hart, Joe Begley, Tristan RichardsonClinical practice/governance and case reports
P86 Cushing’s syndrome -A rare cause of hypertension in pregnancy Maya Venu, Katherine Stanley, Neil Burgess, Francesca SwordsClinical practice/governance and case reports
P87 An Unusual Case of Vitamin D Deficiency and Wernicke-Korsakoff Syndrome. Yee Seun Cheah, Martin Whyte, Simon Aylwin, Jackie GilbertClinical practice/governance and case reports
P88 Phaeochromocytoma / paraganglionoma patients in a joint endocrine genetic clinic setting Sue Stewart, John Ayuk, Chris Campbell, Trevor ColeClinical practice/governance and case reports
P89 Severe Primary Hyperparathyroidism (PHPT) and Osteomalacia in Pregnancy Complicated by Post Parathyroidectomy Hypocalcaemia Related Transient Congestive Cardiac Failure (CCF). Case Report. Natasha Thorogood, Tom Kurzawinski, Gerard Conway, Stephanie BaldewegClinical practice/governance and case reports
P90 Lithium-Induced Hypercalcemia and Parathyroid Dysfunction. Agnieszka Swiecicka, Manjunath MaligeClinical practice/governance and case reports
P91 Failure of Renin Determined by Immunoassay to Suppress in a Case of Adrenocortical Carcinoma Secreting Excess Mineralocorticoid. Thomas Fox, R Mihai, Roy Fisher, John FooteClinical practice/governance and case reports
P92 A case of spontaneously resolving occult ectopic ACTH-dependent Cushing’s syndrome Duncan Browne, John Foote, Thomas FoxClinical practice/governance and case reports
P93 Reasons for treatment changes in hypogonadal men undergoing testosterone replacement. David Dutton, Kate Outterside, Rayin Padinjakara, Martin Weickert, Harpal Randeva, Sailesh SankarClinical practice/governance and case reports
P94 An evaluation of the knowledge, motivation and weight-management service needs of obese young people marc williams, deborah kendall, helena gleeson, rakesh amin, indi banerjee, sarah ehtisham, leena patel, peter clayton, catherine hallClinical practice/governance and case reports
P95 Addison’s Disease – A New Indication for Continuous Subcutaneous Insulin Infusion [CSII]? Rochan Agha-Jaffar, Claire Poulter, David Gable, Stephen RobinsonClinical practice/governance and case reports
P96 Primary Antiphospholipid Syndrome presenting as accelerated hypertension and adrenal haemorrhage associated with elevated urinary catecholamines Ben Thomas, Simon Wordsworth, Neera Agarwal, Steve Davies, Kieron DonovanClinical practice/governance and case reports
P97 The relationship between electrolyte disturbance and treatment with proton pump inhibitors Ana Pokrajac, William StephensClinical practice/governance and case reports
P98 Challenges in management of aggressive GH secreting tumors in adolescents Simona Verzea, Madalina Vintila, Corin BadiuClinical practice/governance and case reports
P99 Vitamin status after gastric bypass and lifestyle intervention: a comparative prospective study Erlend T. Aasheim, Line K. Johnson, Dag Hofsø, Thomas Bøhmer, Jøran HjelmesæthClinical practice/governance and case reports
P113 Is a morning serum cortisol a useful screening test to rule out hypoadrenalism? Ali Chakera, Bijay VaidyaClinical practice/governance and case reports
P114 The Endocrine Consequences of Stem Cell Transplantation Amy Kennedy, Jane Nunnick, Fiona Clark, Charles Craddock, Andrew ToogoodClinical practice/governance and case reports
P115 Endocrinopathy And Low Bone Mineral Density In Thalassaemia Mona Waterhouse, Rebecca Gorrigan, Aldine Thomas, Antonia Brooke, Paul Telfer, Banu Kaya, Scott AkkerClinical practice/governance and case reports
P116 Unemployment and Return to Work after the Diagnosis of a Chronic Endocrine Condition Barbara Alberts, Emily Parker, John WassClinical practice/governance and case reports
P117 THE USE OF THE URINE CALCIUM / CREATININE CLEARANCE RATIO IN PATIENTS WITH HYPERCALCAEMIA Mohammad Mahmud, Channa Jayasena, Fausto Palazzo, Karim Meeran, Waljit DhilloClinical practice/governance and case reports
P118 Salivary Cortisol is a reliable marker to monitor Hydrocortisone replacement Bharat Pahilwani, Sarah Darch, Radha Ramachandran, Jaimini Cegla, Monica Nijher, Karim Meeran, Richard Chapman, Mandy Donaldson, Tricia TanClinical practice/governance and case reports
P119 Screening for glucose intolerance in young women with Polycystic Ovary Syndrome: what is the optimum strategy? Rose-marie Hocking, Aled ReesClinical practice/governance and case reports
P120 The Role of Adrenal Vein Sampling (AVS) in the Diagnosis and Management of Primary Hyperaldosteronism – an Audit of Ten Year’s Experience at a Tertiary Referral Centre. Tom Hopkins, Victoria Salem, Heba El-Gayar, Tricia Tan, Fausto Palazzo, Kareem MeeranClinical practice/governance and case reports
P121 Peripheral blood mononuclear cells from active rheumatoid arthritis patients show a defective induction of Adrenomedullin. Laura Green, Andrew Berry, Rachelle Donn, David RayCytokines and growth factors
P122 Impact of adiposity on dynamic changes of serum adipokines after OGTT Moulinath Banerjee, Phillip Pemberton, Valentyn Charlton-Menys, William Fraser, Kennedy CruickshankCytokines and growth factors
P123 Interaction of endothelin, aldosterone and bone morphogenetic proteins on mitotic actions of pulmonary arterial smooth muscle cells isolated from pulmonary arterial hypertension Fumio Otsuka, Ryutaro Yamanaka, Kazufumi Nakamura, Misuzu Yamashita, Masaya Takeda, Jiro Suzuki, Tomoko Miyoshi, Kenichi Inagaki, Hirofumi MakinoCytokines and growth factors
P124 PTTG promotes mitogenic mechanisms in thyroid cells through autocrine pathways of interaction with TGF-alpha , EGF and IGF-1 Greg Lewy, Gavin Ryan, Martin Read, Vicki Smith, Jim Fong, Adrian Warfield, Margaret Eggo, Robert Seed, Neil Sharma, Kwan Perkin, Jayne Franklyn, Christopher McCabe, Kristien BoelaertCytokines and growth factors
P125 Does SOCS2 Mediate Inflammatory Induced Growth Retardation? Chloe Pass, Vicky MacRae, Syed Ahmed, Colin FarquharsonCytokines and growth factors
P126 Differential effects of eicosapentaenoic acid (EPA) and Palmitate on tumour necrosis factor (TNF-alpha) and insulin-like growth factor (IGF-I) action in murine skeletal muscle cells Amarjit Saini, Nasser Al-Shanti, Claire StewartCytokines and growth factors
P127 Atrophy or Hypertrophy: Differential Responses of C2 and C2C12 Mouse Skeletal Myoblasts in the Absence or Presence of Tumour Necrosis Factor-Alpha (TNF-α). Adam Sharples, Nasser Al-Shanti, Claire StewartCytokines and growth factors
P128 Blood Pressure, Renal Cytokines and Biochemical Parameters Improve in Morbidly Obese Patients after Bariatric Surgery Sukhpreet Singh Dubb, Marco Bueter, Abhijit Gill, Ahmed R Ahmed, Andrew Frankel, Carel W Le Roux, Frederick TamCytokines and growth factors
P129 PROFILE OF ELDERLY PATIENTS WITH DIABETES ADMITTED INTO OBAFEMI AWOLOWO UNIVERSITY TEACHING HOSPITAL ROSEMARY IKEM, DAVID SOYOYE, JOSEPH ADEBAYO, BUSOLA OJO, EJIOFOR UGWU, BABATOPE KOLAWOLEDiabetes, metabolism and cardiovascular
P130 Factitious hypoglycaemia in a patient without diabetes Monika Reddy, Craig Leaper, Upkar Drubra, Ali Abbara, Yetunde Baoku, Daniel Darko, Sanjeev MehtaDiabetes, metabolism and cardiovascular
P133 Pancreatic Polypeptide: A novel substrate for the endopeptidase neprilysin. Jordan Baxter, James Minnion, Joy Shilto-Cuenco, Tricia Tan, Kevin Murphy, Mohammad Ghatei, Stephen BloomDiabetes, metabolism and cardiovascular
P134 BARIATRIC SURGERY IN RENAL TRANSPLANT RECIPIENTS Salma S. Kamaledeen, Marco Bueter, Ahmed Ahmed, Carel W Le RouxDiabetes, metabolism and cardiovascular
P135 Testosterone replacement therapy has no effect on ultrasound assessed carotid artery stiffness and intima-media thickness in men with insulin treated type 2 diabetes Roger Stanworth, T Hugh JonesDiabetes, metabolism and cardiovascular
P136 A novel role for neuropeptide Y in the regulation of energy homeostasis Emma Leavy, James Gardiner, Niki Buckley, Errol Richardson, Niamh Martin, Stephen Bloom, Kirsty SmithDiabetes, metabolism and cardiovascular
P137 Salicylate induces insulin sensitivity by alleviating Endoplasmic Reticulum (ER) stress in cultured primary human adipocytes Gyanendra Tripathi, Saif Alhusaini, Kirsty McGee, Kostantinos Lois, Alison Harte, Philip McTernan, Sudhesh KumarDiabetes, metabolism and cardiovascular
P138 Herbal Remedies as a cause of Recurrent Hypoglycaemia Thompson Whitfield, Subhash Rana, Vijay Bangar, Abdusalam MousaDiabetes, metabolism and cardiovascular
P140 The impact of thiazolidinediones on microalbuminuria in adults with type 2 diabetes mellitus: a systematic review. Mayur Patel, Robert Fowkes, Mike Sampson, Richard HollandDiabetes, metabolism and cardiovascular
P141 Diabetic Keto-Acidosis in patients with Type 2 Diabetes Mellitus: a relatively common occurrence, the severity of which correlates with HbA1C Helen Begbie, Thomas Barber, Narendra Reddy, Hugh SimpsonDiabetes, metabolism and cardiovascular
P142 Healthcare Professionals Frequently Fail to Recognise Severe Obesity Tomas Ahern, Anne McGowan, Maeve Davis, Astrid Billfalk-Kelly, Donal O'SheaDiabetes, metabolism and cardiovascular
P143 Starvation ketoacidosis in pregnancy Charlotte Frise, Lucy MackillopDiabetes, metabolism and cardiovascular
P144 Protective effects of annexin A1 in experimental endotoxaemia are mediated by an FPR-dependent mechanism. Ellen L Hughes, Julia C Buckingham, Felicity NE GavinsDiabetes, metabolism and cardiovascular
P145 Study of Toll-like receptor 2 (TLR2) as a biomarker for cardiovascular diseases in type 2 diabetes mellitus Patients Gihan Mohamed Kamal, Rania Sayed Abd ElBaki, Rehab Saleh ElHagrasi, Rasha Yousif Shaheen, Dina Mohamed SamirDiabetes, metabolism and cardiovascular
P146 Regulation of the Melanocortin receptor accessory protein (MRAP) in Y1 adrenal cells Imran Siddiq, Teng-Teng Chung, Adrian ClarkDiabetes, metabolism and cardiovascular
P147 Annexin 1 Affords Cerebroprotection in Sepsis Felicity Gavins, Ellen Hughes, Honeysha Patel, Julia BuckinghamDiabetes, metabolism and cardiovascular
P148 THE LIPOPROTEINLIPASE HINDIII POLYMORPHISM AND SUSCEPTIBILITY TO HYPERTENSION NEVEEN HEMIMI, MONA ABD-ELSALAM, MAHMOUD ABD-ELWAHABDiabetes, metabolism and cardiovascular
P150 Diabetic Ketoacidosis: A 5-year retrospective analysis. Triona O'Shea, Marie Louise Healy, John Nolan, Siobhan McQuaidDiabetes, metabolism and cardiovascular
P151 Effect of Rimonabant and metformin on oxidative stress in obese patients with polycystic ovary syndrome (PCOS) Myint M Aye, John Shepherd, Liwei Cho, JM Ng, Anne Marie Coady, Eric S Kilpatrick, Stephen L Atkin, Thozhukat SathyapalanDiabetes, metabolism and cardiovascular
P152 At high dietary fat levels, dietary fish–oil may enhance metabolic efficiency but may favour a reduction in the deposition of adipose tissue. Michelle Sleeth, Emily Thompson, Jelena Anastasovska, Jimmy Bell, Gary FrostDiabetes, metabolism and cardiovascular
P153 A role for aquaglyceroporins in adipogenesis James Brown, Matthew Conner, Roslyn Bill, Manjunath Ramanjaneya, Clifford Bailey, Harpal Randeva, Alex ConnerDiabetes, metabolism and cardiovascular
P154 Infidelity of ectopic transcription using a pseudo splice site: lessons from HNF-1beta mutation causing familial juvenile hyperuricaemic nephropathy Sian Piret, Anita Reed, Jennifer Reilly, Neil Turner, Rajesh ThakkerDiabetes, metabolism and cardiovascular
P155 Patients with Turner Syndrome have a high incidence of metabolic abnormalities. Sara Syed, Jane MacDougall, Helen SimpsonDiabetes, metabolism and cardiovascular
P156 Impact of extra cellular matrix changes on adipogenesis Lei Zhang, Robert Steadman, Anna de Lloyd, Jack Ham, Aled Rees, Marian LudgateDiabetes, metabolism and cardiovascular
P158 Nuf mice with an activating calcium sensing receptor mutation, Leu723Gln, have a metabolic acidosis and impaired urinary acidification Fadil Hannan, M. Andrew Nesbit, Chris Esapa, Simona Di Pretoro, Mary Lyon, Roger Cox, Rajesh ThakkerDiabetes, metabolism and cardiovascular
P159 Brain natriuretic peptide shows no response to acute hypobaric hypoxia in humans David Woods, Tim Hooper, Adrian Mellor, Pete Hodkinson, Rob Wakeford, Bob Peaston, Steve Ball, Nic GreenDiabetes, metabolism and cardiovascular
P160 Total pancreatectomy and pancreatic islet autotransplantation in patient with intractable pain caused by chronic pancreatitis Thang Han, Shna Abdurahman, Gareth Jones, Anila Kumar, Mark Lowdell, Julian Pratt, Stephen Powis, Keith Rolles, Miranda Rosenthal, Martin Press, Tomasz KurzawinskiDiabetes, metabolism and cardiovascular
P161 Weight and glycaemic outcomes following bariatric surgery in people with type 2 diabetes. Yared N Demssie, Jhalini Jawaheer, Seleena Farook, John P New, Akheel A SyedDiabetes, metabolism and cardiovascular
P162 Effect of Ramadan fasting on glycaemic control in type 2 diabetic patients on oral hypoglacaemic agents. Abdolreza Norouzy, Mohsen Nematy, Maryam Sabery, Mohammad Reza Mohajeri, Farnaz Shakeri, Sara YariDiabetes, metabolism and cardiovascular
P163 An exploration of the predictive factors for the early pleiotropic responses to exenatide therapy in patients with type 2 diabetes mellitus Thomas Barber, Narendra Reddy, Helen Begbie, Naseem Sophal, Carol McCulloch, Angela Rogers, Auditi Naziat, Diptendra Ghosh, Mamoun Mukhtar, Hugh SimpsonDiabetes, metabolism and cardiovascular
P164 Expression of store-operated Orai channels in normal and diabetic kidney Andrew Green, Sunil Bhandari, Neil Watson, Steve Atkin, Shang-Zhong XuDiabetes, metabolism and cardiovascular
P165 METABOLIC PHENOTYPE IN BROTHERS` OF WOMEN WITH POLYCYSTIC OVARIAN SYNDROME Mohammad Siddiqui, Mukul Gupta, Subhash WangnooDiabetes, metabolism and cardiovascular
P166 Nuf mice with an activating calcium-sensing receptor mutation, Leu723Gln, have impaired glucose tolerance and reduced insulin secretion Fadil Hannan, M. Andrew Nesbit, Liz Bentley, Roger Cox, Rajesh ThakkerDiabetes, metabolism and cardiovascular
P167 Liraglutide prevents endothelial damage triggered by glucose oscillations. Bruno Schisano, Claire Radford, Allison Harte, Phillip Mc TernanDiabetes, metabolism and cardiovascular
P168 Glucocorticoid and Insulin Regulation of Lipid Metabolism in Human Adipocytes Laura Gathercole, Iwona Bujalska, Stuart Morgan, Dave Hauton, Paul Stewart, Jeremy TomlinsonDiabetes, metabolism and cardiovascular
P169 MOPDII and Alström Syndrome: two centrosomopathies featuring severe insulin resistance and impaired adipogenesis Isabel Huang-Doran, Keith Porter, Stephen O'Rahilly, Andrew Jackson, Robert SempleDiabetes, metabolism and cardiovascular
P170 A Novel Syndrome of IGF-1 and Insulin Supersensitivity Isabel Huang-Doran, Matthijs Groeneveld, Hemantha Chandrasekera, Keith Porter, Stephen O'Rahilly, Sid McNulty, Niall Furlong, Robert SempleDiabetes, metabolism and cardiovascular
P171 Biomarkers of the hypothalamic-pituitary-adrenal (HPA) axis for analysis of in vivo 11β-hydroxysteroid dehydrogenase 1 inhibition Erika Harno, Alice Yu, Brendan Leighton, Andrew Turnbull, Anne WhiteDiabetes, metabolism and cardiovascular
P172 ALDOSTERONE PRODUCTION BY THE MOUSE ADRENAL GLAND IS COMPROMISED BY A HIGH FAT DIET AND 11Β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 DEFICIENCY Frida Nilsson, Hamish Morrison, Lynne Ramage, Nicholas Morton, Jonathan Seckl, Steven Morley, Christopher KenyonDiabetes, metabolism and cardiovascular
P174 Low Testosterone Level Is Associated With Significant Increase In Mortality In Patients With Type 2 Diabetes Vakkat Muraleedharan, Hazel Marsh, Hugh JonesDiabetes, metabolism and cardiovascular
P176 Testosterone Replacement May Be Beneficial In Hypogonadal Men With Cardiovascular Disease Vakkat Muraleedharan, Caroline Dugdale, Roger Stanworth, Hugh JonesDiabetes, metabolism and cardiovascular
P177 Mice harbouring the Familial Juvenile Hyperuricaemic Nephropathy (FJHN) disease-causing Uromodulin (Tamm-Horsfall Glycoprotein) mutation Cys125Arg, have a urine concentrating defect, progressive renal failure, and altered uric acid handling. Sian Piret, Anita Reed, M. Andrew Nesbit, Tertius Hough, Liz Bentley, Roger Cox, Rajesh ThakkerDiabetes, metabolism and cardiovascular
P178 Investigating the role of ventromedial hypothalamic glucose-sensing neurones in the response to hypoglycaemia. Errol Richardson, Syed Sufyan Hussain, John Robert Counsell, Gavin Bewick, Stephen Bloom, James GardinerDiabetes, metabolism and cardiovascular
P179 Functional muscarinic acetylcholine receptors are expressed in white and brown adipose tissue Mark Stephens, Aled Rees, Marian LudgateDiabetes, metabolism and cardiovascular
P180 Impact of Glucocorticoids upon Lipogenesis and β-Oxidation in Skeletal Muscle Stuart Morgan, Laura Gathercole, Paul Stewart, Dave Smith, Jeremy TomlinsonDiabetes, metabolism and cardiovascular
P181 The Influence of HIV Status and Antiretroviral (ARV) Therapy on Expression of Genes Related to Mitochondrial Metabolism in Human Adipose Tissue (AT). Kirsty McGee, Meg Boothby, Alison Harte, Jeremy Tomlinson, Margaret Hill, Laura Gathercole, Sudhesh Kumar, Mohsen Shahmanesh, Philip McTernanDiabetes, metabolism and cardiovascular
P182 Deficiency in 11β-hydroxysteroid dehydrogenase type 1 reduces systemic inflammation and inflammatory cell infiltration in atherosclerotic lesions of ApoE-/- mice Tiina Kipari, Tak-Yung Man, Patrick Hadoke, Christopher White, Karen Chapman, Jonathan SecklDiabetes, metabolism and cardiovascular
P183 Short Sleep Duration is Independently Associated with Obesity in with Type 2 Diabetes Abd Tahrani, Safia Begum, Shanaz Mughal, Kiran Dubb, Dev Banerjee, G Neil Thomas, Asad Ali, Biju Jose, Milan Piya, Martin Stevens, Anthony barnett, Shahrad TaheriDiabetes, metabolism and cardiovascular
P184 Vitamin D status independently associates with aortic stiffness in South Asians – a novel risk factor for cardiovascular disease? David Webb, Melanie Davies, Kamlesh KhuntiDiabetes, metabolism and cardiovascular
P185 Diet-induced obesity in C57Bl/6 mice is associated with sex-specific changes in glucocorticoid metabolism Rachel Dakin, Patrick Hadoke, Jonathan Seckl, Brian Walker, Amanda DrakeDiabetes, metabolism and cardiovascular
P186 Circadian rhythmicity is altered in hepatic corticosterone-related genes from diet induced obese mice Erika Harno, Alice Yu, Henry Brown, Andrew Turnbull, Brendan Leighton, Anne WhiteDiabetes, metabolism and cardiovascular
P187 Down-regulation of adipose 11βHSD1 mediates the insulin sensitising effects of salicylate in obesity Mark Nixon, Dawn Livingstone, Ruth Andrew, Brian WalkerDiabetes, metabolism and cardiovascular
P189 Laparoscopic versus Open Adrenalectomy and Adjuvant Mitotane in Adrenocortical Carcinoma Sarah Ali, Asjid Qureshi, Ian Clarke, Fausto PalazzoEndocrine tumours and neoplasia
P190 An unusual presentation of Insulinoma with postabsorptive Hypoglycaemia? Joachim Stolte, Amalia Iliopoulou, Simon Holmes, Dinesh NagiEndocrine tumours and neoplasia
P191 A family with functional extraadrenal paragangliomas and positive SDHB gene mutation Doro Polydorou, Sami Kenz, Daniel Kannapan, Tara KearneyEndocrine tumours and neoplasia
P193 2 cases of Meningitis as a complication of pituitary adenoma Horng Kai Tan, Acharya Jayashekara, Daniel FlanaganEndocrine tumours and neoplasia
P194 A case of Phaeochromocytoma mimicking an acute ischemic limb - An unusual presentation Ridwan Ahmed, U Y Raja, Bheemasenachar Prasad, Matthew Rooney, R Govindan, Harish Kumar, Sharad Karandikar, Jayadave ShakherEndocrine tumours and neoplasia
P195 Ectopic Cushings complicated by paraneoplastic cerebral vasculopathy requiring high-dose steroid therapy. Alice Jordan, John Parr, Cecil Thomas, Shahid WahidEndocrine tumours and neoplasia
P196 Cranioplasty for extensive skull deposit in the management of differentiated thyroid cancer. Sudeep Putta-Manohar, Abby Cyriac, Rachel Pearson, Ujjal Mallick, Petros PerrosEndocrine tumours and neoplasia
P197 Pseudophaeochromocytoma syndrome associated with Modafinil Nyi Htwe, Koshy JacobEndocrine tumours and neoplasia
P198 An Unusual Case of Rapidly Progressing Pituitary Lesion Rashmi Manjunatha, Ullal Ananth Nayak, Senthil Krishnaswamy, Harit BuchEndocrine tumours and neoplasia
P199 Cinacalcet treatment of resistant hypercalcaemia due to MEN1-associated primary hyperparathyroidism in pregnancy Barbara Wysota, Stephanie Horne, Angharad Smyth, Aresh Anwar, Sailesh Sankar, Martin WeickertEndocrine tumours and neoplasia
P200 A case of Carcinoid Syndrome without liver metastasis Nilushi Ranaweera, Tristan RichardsonEndocrine tumours and neoplasia
P201 Choroidal Malignant Melanoma in a patient with Carney Complex Seleena Farook, Christine Gibson, Julian DavisEndocrine tumours and neoplasia
P202 A rare case of steroid responsive non-islet cell tumour hypoglycemia (NICTH) secondary to metastatic haemangiopericytoma Aung Mon, Rupa Ahluwalia, Saffia Tehseen, Ali Rathore, Philip Weston, Aftab AhmadEndocrine tumours and neoplasia
P203 Adrenal Venous Sampling for Catecholamines: A Normal Value Study E Marie Freel, Anthony Stanson, Geoffrey Thompson, Clive Grant, David Farley, Melanie Richards, William YoungEndocrine tumours and neoplasia
P204 Temozolomide-induced regression of hepatic metastases in a pituitary corticotroph carcinoma with low O6-methylguanine-DNA methyltransferase (MGMT) expression Hannah Burton, Anand K Annamalai, Andrew Dean, Kalman Kovacs, Nagui Antoun, Ramez W Kirollos, Helen L Simpson, Sarah J Jeffries, Neil G Burnet, Mark GurnellEndocrine tumours and neoplasia
P205 Secretory glomus jugulare tumour treated with steriotactic radio surgery RN KULAMBIL PADINJAKARA, SUBASH SIVARAMAN, DAVID DUTTON, NPN MURTHY, MARTIN WEICKERT, ATEEQ SAYED, HARPAL RANDEVA, SAILESH SHANKAREndocrine tumours and neoplasia
P206 Case Report; Multiple Endocrine Neoplasia type 2A and Hereditary Haemorrhagic Telangiectasia Presenting Consecutively in a Single Patient Hussein O, Crowley R, Sheahan P, Brady A. Tuthill A. Omer Hussein, Rachel Crowley, Patrick Sheahan, Adrian Brady, Antoinette TuthillEndocrine tumours and neoplasia
P207 PARATHYROIDECTOMY HAS NO IMPACT ON HAEMOGLOBIN LEVELS ON PATIENTS WITH PRIMARY HYPERPARATHYROIDISM Siva Sundar, Gregory Sadler, Radu MihaiEndocrine tumours and neoplasia
P208 LOW INCIDENCE OF HYPOCALCAEMIA AFTER THYROIDECTOMY IN PATIENTS ADMINISTERED ROUTINELY ORAL CALCIUM SUPPLEMENTS Jan Herzog, Radu MihaiEndocrine tumours and neoplasia
P209 Utilization of various imaging modalities in the localization of tumours in MEN-1 and insulinoma. Claire Ma, Dimuthu Muthukuda, Nicholas Carroll, Sobhan Whitley, Helen SimpsonEndocrine tumours and neoplasia
P210 Functional characterisation of aryl hydrocarbon receptor interacting protein (AIP) promoter and silent mutations Susana Igreja, Harvinder Chahal, Peter King, Graeme Bolger, Umasuthan Srirangalingam, Leonardo Guasti, Paul Chappel, Maria Gueorguiev, Katie Guegan, Karen Stals, Bernard Khoo, Ajith Kumar, Sian Ellard, Ashley B. Grossman, Márta KorbonitsEndocrine tumours and neoplasia
P211 Investigating the role of HIF-1α in tumour growth and metastasis in an in vivo model of thyroid cancer Natalie Burrows, Julia Resch, Melissa Mejin, Georg Brabant, Kaye WilliamsEndocrine tumours and neoplasia
P212 ROUTINE CENTRAL COMPARTMENT LYMPH NODE DISSECTION FOR PAPILLARY THYROID CANCER HAS MINIMAL IMPACT ON EARLY POSTOPERATIVE PARAMETERS Rajeev Parameswaran, Michael Stechman, Andrew Weaver, Gregory Sadler, Radu MihaiEndocrine tumours and neoplasia
P213 Concordance between Thyroglobulin antibody assays. Damon Parkington, Sonia Littleboy, Kevin Taylor, Sarah Jeffries, Helen Simpson, David HalsallEndocrine tumours and neoplasia
P214 Mutations of the transcription factor, GATA3, in Oestrogen Receptor positive Breast Cancers. Katherine Gaynor, Irina Grigorieva, Chris Esapa, Rosie Head, Paul Christie, Andrew Nesbit, Louise Jones, Rajesh ThakkerEndocrine tumours and neoplasia
P215 Receptor-based scintigraphic imaging of insulinoma and glucagonoma in MEN-1. Sivasubramaniam Sivappriyan, Tom Kurzawinski, Jamshed Bomanji, Gerard Conway, James AhlquistEndocrine tumours and neoplasia
P216 Expression and regulation of oestrogen sulfotransferase (EST) in human ovarian surface epithelium (OSE) and epithelial ovarian cancer (EOC). Xia Ren, Chris Harlow, Scott Fegan, Ian Mason, Hilary Critchley, Stephen HillierEndocrine tumours and neoplasia
P217 IS THE ANTI-PROLIFERATIVE EFFECT OF AIP (ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN) VIA ZAC TRANSCRIPTION FACTOR? Neda Alband, Susanna Igreja, Harvinder S. Chahal, Ashley. B Grossman, Marta KorbonitsEndocrine tumours and neoplasia
P218 The role of PBF in NIS and MCT8 cellular trafficking Vicki Smith, Martin Read, Rachel Watkins, Gregory Lewy, Jim Fong, Robert Seed, Neil Sharma, Gavin Ryan, Kristien Boelaert, Jayne Franklyn, Christopher McCabeEndocrine tumours and neoplasia
P219 MEN2B patients with a RET A883F mutation have less aggressive MTC than those with the common RET M918T mutation Gabriella Worth, Fausto Palazzo, Neil Tolley, Stephen Robinson, Jeremy Cox, Graham Williams, Duncan BassettEndocrine tumours and neoplasia
P220 First report of SOX2 loss of function associated with a large hypothalamo-pituitary tumour; further insights into the role of SOX2 in pituitary development. Kyriaki S Alatzoglou, Maria Cristina Arriazu, John Crolla, Juan Pedro Martinez-Barbera, Martin Roubicek, Charles Buchanan, Mehul T. DattaniEndocrine tumours and neoplasia
P221 Pro-opiomelanocortin (POMC) is a novel biomarker for small cell lung cancer. Rachel Stovold, Adam Stevens, David Ray, Paula Sommers, Caroline Dive, Fiona Blackhall, Anne WhiteEndocrine tumours and neoplasia
P222 Parafibromin, a tumour suppressor protein, interacts with transforming acidic coiled coil protein 3 (TACC3) and kinesin family member 5B (KIF5B) Paul Newey, Michael Bowl, Fanni Gergely, Rajesh ThakkerEndocrine tumours and neoplasia
P223 Open or Laparoscopic Surgery for Phaeochromocytoma Tarek Ezzat, James Skipworth, Dimitris Raptis, Gerard Conway, Stefie Baldweg, Jamshed Bomanji, Pierre Bouloux, Keith Rolles, Bernard Khoo, Penny Hyatt, Michaela Rossi, Maria Barnard, Karen Anthony, Nemanja Stojanovic, Mark Cohen, Jonathan Katz, Christopher Baynes, Sabina Russel, James Ahlquist, Tom KurzawinskiEndocrine tumours and neoplasia
P224 PBF is induced by ionising radiation and functionally inactivates p53 in thyroid cancer Robert Seed, Martin Read, Jim Fong, Gregory Lewy, Vicki Smith, Rachel Watkins, Perkin Kwan, Neil Sharma, Gavin Ryan, Jayne Franklyn, Kristien Boelaert, Christopher McCabeEndocrine tumours and neoplasia
P225.1 The microRNA let-7a is downregulated in pituitary tumours from a Multiple Endocrine Neoplasia type-1 (MEN1) mouse model Rebecca Dyar, Paul Newey, Andrew Nesbit, Gerard Walls, Rajesh ThakkerEndocrine tumours and neoplasia
P225 MITOTANE TREATMENT HAS PROFOUND EFFECTS ON CORTISOL CATABOLISM. Lea Ghataore, Hagosa Abraha, Indrani Chakraborti, Norman Taylor, Simon Aylwin, K-M SchulteEndocrine tumours and neoplasia
P226 Klinefelter’s Syndrome Often Remains Undiagnosed or Diagnosed Late Subhash Rana, Joan Adiotomre, Vijay Bangar, Abdusalam MousaGrowth and development
P227 Altered Responses to GH and IGF-I in Children Born Small for Gestational Age Without Post- Natal Catch Up Growth Imogen Butcher, Andrew Whatmore, Philip Murray, Melissa Westwood, Peter ClaytonGrowth and development
P228 Delayed puberty in children with inflammatory bowel disease may be associated with gonadotrophin resistance Jarod Wong, Avril Mason, Richard Russell, Paraic McGrogan, Jonathan Bishop, Faisal AhmedGrowth and development
P229 Familial Growth Hormone Deficiency - Response to Growth Hormone Therapy & Analysis of the GH-1 and GHRH-R genes Mark Hannon, Vivian Crowley, Domhnall O'HalloranGrowth and development
P230 The Impact of IBD on Pubertal Growth is Most Marked in Boys with Crohn’s Disease Avril Mason, Paraic McGrogan, Richard Russell, Jonathan Bishop, Salma Malik, Faisal AhmedGrowth and development
P231 Phenotypic presentation of P450 oxidoreductase deficiency during puberty Jan Idkowiak, Stephen O'Riordan, Nicole Reisch, Vivek Dhir, Ewa Malunowicz, Michiel Kerstens, Dominique Maiter, Felicity Collines, Martin Silink, Mehul Dattani, Cedric Shackleton, Nils Krone, Wiebke ArltGrowth and development
P232 Loss of the Golgi Localised E3 Ubiquitin Ligase containing Cullin 7 in the Growth Disorder 3-M syndrome leads to Reduced Cell Proliferation and Reduced IGF-1 mediated Activation of Akt Philip Murray, Daniel Hanson, Amit Sud, Ajibola Omokanye, Waqas Khan, Naz Khan, Kate Chandler, Mona Aglan, Graeme Black, Peter ClaytonGrowth and development
P233 A novel dominant-negative Glial Cells Missing B (GCMB) mutation (Asn502His) is associated with autosomal dominant hypoparathyroidism and results in reduced transactivation activity. Michael Bowl, Samantha Mirzcuk, Carl Fratter, Treena Cranston, Jeremy Allgrove, Caroline Brain, Andrew Nesbit, Rajesh ThakkerGrowth and development
P234 Sleep is Frequently Disordered in Patients Irradiated for Brain Tumours Rowena Abraham, Ilonka Kreitschmann-Andermahr, Kashinet Dixit, Ric Swindell, Georg BrabantNeuroendocrinology and behaviour
P235 Intra Cerebral Haemorrhage in a young woman with Phaeochromocytoma. Sami Kenz, Daniel Kanappan, Doros polydorou, Tara KearneyNeuroendocrinology and behaviour
P236 The endocrine and behavioural effects of high fat feeding Alison McNeilly, David Balfour, Caroline StewartNeuroendocrinology and behaviour
P237 Profiling the metabolic clearance and enzymatic degradation of the gut hormone Peptide YY as a tool to design long-acting PYY3-36 analogues in treating obesity Melisande Addison, Emily Thompson, James Minnion, Kevin Murphy, Samar Ghourab, Klara Hostomska, Mohammad Ghatei, Stephen BloomNeuroendocrinology and behaviour
P238 Characterising the role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1 ) in viral meningitis James Lai, Graham Wallace, Lei Liu, Radhika Susarla, Khillan Shah, Paul Stewart, Elizabeth Walker, Saaeha Rauz, Alexandra SinclairNeuroendocrinology and behaviour
P239 ALARIN STIMULATES FOOD INTAKE AND THE HYPOTHALAMO-PITUITARY-GONADAL AXIS IN MALE RATS Charlotte Boughton, Michael Patterson, Gavin Bewick, John Tadross, James Gardiner, Faizan Chaudery, George Hunter, Mohammad Ghatei, Stephen Bloom, Kevin MurphyNeuroendocrinology and behaviour
P240 Transgenic disruption of 5alpha-reductase 1 in mice results in a blunted stress response Dawn Livingstone, Yang Chenjing, Di Rollo Emma, Kara Madina, Mathews John, Codrington Lucy, Kenyon Christopher, Walker Brian, Andrew RuthNeuroendocrinology and behaviour
P241 Stress hormone response in men at high altitude: effect of ethnicity Meenakshi Sachidhanandam, Som Nath Singh, Ashok Kumar Salhan, UdaySankar RayPituitary
P242 Hypopituitarism secondary to Pituitary Apoplexy- Is it due to high dose Aspirin?? DANIEL KANNAPPAN, DOROS POLYDOROU, SAMI KENZ, ANGELA PAISLEY, TARA KEARNEYPituitary
P243 Not Every Pituitary Apoplexy is Caused By Pituitary Haemorrhage Gideon Mlawa, Khalifa ShaafiPituitary
P246 Management of Diabetes Insipidus during pregnancy. Atif Munir, Anjali Santhakumar, Vincent ConollyPituitary
P247 Thyrotropin-secreting pituitary tumour causing high output cardiac failure Julie Kyaw Tun, Haliza Haniff, Cornelle ParkerPituitary
P248 Is it Pituitary adenoma Or Metastasis?- An unusual presentation of Carcinoma Prostate DANIEL KANNAPPAN, SAMI KENZ, DOROS POLYDORO, TARA KEARNEY, KANNA GNANALINGHAMPituitary
P249 Sub-optimal Testosterone replacement in Acromegaly Mohammed Choudhury, Tristan RichardsonPituitary
P250 TSH-secreting pituitary adenoma: potential benefits of pre-operative octreotide. Ian Wallace, Estelle Healy, Steve Cooke, Roy Harper, Steven HunterPituitary
P251 An uncommon cause of hypopituitarism VARUN BUCH, SENTHILKUMAR KRISHNASAMY, SANJAY VYDIANATH, VARADARAJAN BASKAR, JOHN MATHEWS, HARIT BUCHPituitary
P252 Herpes encephalitis causing hypopituitarism Krishnamurthy Chikkaveerappa, Ian MacfarlanePituitary
P253 The effects of 3 year growth hormone replacement on the lipid profile of adults with growth hormone deficiency using a fixed graded initiation, followed by a titration phase method: 3-year retrospective analysis Victor Oguntolu, Simon AylwinPituitary
P254 Adverse prognosis in breast cancer patients who develop pituitary metastases Simeen Akhtar, Simon J Howell, Kalpana KaushalPituitary
P255 High Incidence Of Survivors Of Childhood Malignancy In An Endocrine Transition Service Anna-Louise Dennis, Carol Acerini, Helen SimpsonPituitary
P256 Hypopituitarism following Russell’s Viper Bite: A case Report Charles Antonypillai, John Wass, Henry RajarantamPituitary
P257 Carcinomatous change in a craniopharyngioma: a case report Simeen Akhtar, Aprajay Golash, Windsor Gunawardena, Andrew Hindley, Simon HowellPituitary
P258 Outcome of treatment for patients with acromegaly in a single referral centre Sanjaya Dissanayake, Kate Millar, Kalpana Kaushal, Simon HowellPituitary
P259 An interesting case of intrasellar cavernous carotid aneurysm mimicking pituitary adenoma. Cynthia Mohandas, Ian ScobiePituitary
P260 Solitary pituitary metastasis from carcinoma of the prostate – A case report Seleena Farook, Kanna Gnanalingham, Pyali Pal, Tara KearneyPituitary
P262 Prolonged remission of acromegaly after cessation of somatostatin analogue treatment Vivien Thornton-Jones, Niki Karavitaki, John A H WassPituitary
P263 Spontaneous remission of Cushing’s Disease: apoplexy of a pituitary microadenoma? Paolo Dalino Ciaramella, Erika Grossrubatscher, Paola LoliPituitary
P264 Both acetylcholine and choline stimulate externalisation of annexin 1 from S100-positive folliculo-stellate cells of the pituitary gland Damian Lees, John Morris, Susan Greenfield, Helen ChristianPituitary
P265 Gender differences in presentation and response to treatment for prolactin-secreting adenoma Sara Luck, Paul Carroll, Jake Powrie, Barbara McGowan, Stephen ThomasPituitary
P266 Cabergoline therapy is associated with successful abolition of abnormal cycles of excess steroid excretion in a case of pituitary dependent Cushing’s disease Una Graham, Karen Mullan, Hiliary Leslie, Peter Ellis, A Brew AtkinsonPituitary
P267 Endocrine Outcomes of Pituitary Surgery Kate Millar, Sanjaya Dissanayake, Kaushik Ghosh, Nisha Kaimal, David Walmsley, Kalpana Kaushal, Simon HowellPituitary
P268 Recurrent meningitis secondary to an invasive TSH oma A Santhakumar, V ConnollyPituitary
P269 When should an MRI pituitary scan be performed in hypogonadal men with low or low normal LH? Emma Rigby, Hugh JonesPituitary
P270 Hypothalamic resistance to signals of energy reserve, rather than excess appetite stimulation, may contribute to obesity in CP patients Rachel K Crowley, Patricia Barrett, Conor Woods, Michelle Fleming, LucyAnn Behan, Eoin P O'Sullivan, Bairbre Rogers, Amar Agha, Diarmuid Smith, Christopher J ThompsonPituitary
P271 The effect of pituitary surgery on VEGF, MMP 2 and MMP 9 levels in acromegaly and non-functioning pituitary adenomas. Haiju Chirayath, Julia Hoppmann, Harpal Randeva, John WassPituitary
P272 Obesity and cardiovascular risk factors in adult patients with acquired structural hypothalamic damage. Caroline Steele, Ian MacFarlane, Mohsen Javadpour, Christina DaousiPituitary
P273 The R304X mutation of the Aryl hydrocarbon receptor interacting protein (AIP) gene in familial isolated pituitary adenomas: mutational Hot-Spot or founder effect? Giampaolo Trivellin, Gianluca Occhi, Marie-Lise Jaffrain-Rea, Nora Albiger, Filippo Ceccato, Ernesto De Menis, Mariolina Angelini, Sergio Ferasin, Franco Mantero, Albert Beckers, Carla ScaroniPituitary
P274 Rathke’s cleft cysts in need of regular follow-up in case of recurrence Raluca Trifanescu, Alexandra Mandecka, Haiju Chirayath, Olaf Ansorge, Simon Cudlip, John AH Wass, Niki KaravitakiPituitary
P275 Recurrence rates in patients with non-functioning pituitary adenomas presenting with acute apoplexy: a long-term follow-up study Aparna Pal, Niki Karavitaki, Christina Capatina, Alma Tenreiro, Patricia Guardiola, John WassPituitary
P276 Pituitary gonadotrophinoma and ovarian hyperfunctioning: link or coincidence? Rajeev Raghavan, Suzanne Phillips, Jo Bailey, Richard Nelson, Andrew Levy, Karin BradleyPituitary
P277 Somatotroph adenoma subtype and responsiveness to somatostatin analogues in patients with acromegaly Raghava Reddy Gubbihal, Niki Karavitaki, Olaf Ansorge, Vivien Thornton-Jones, John AH WassPituitary
P278 Remission rate in microprolactinomas treated with dopamine agonists Monica Livia Gheorghiu, Raluca Trifanescu, Andra Caragheorgheopol, Dan Hortopan, Anda Dumitrascu, Mihai CoculescuPituitary
P279 Echocardiography in patients with hyperprolactinaemia treated with dopamine agonists. What happens in daily clinical practice and what do we find? Audrey Soo, Stephanie E BaldewegPituitary
P280 Treatment experience in 11 patients with Gigantism. Claire E Higham, Phillipe Emy, Diego Ferone, Reinhard Finke, Peter Laurberg, Katharina Main, P Maffei, C Martini, Francesco Minuto, Isabelle Rainegard, Kirsten Salzgeber, C Vogel, Maria Koltowska-Haggstrom, Peter J TrainerPituitary
P281 The actions of long term opioids for persistent pain on anterior pituitary hormones Victor Oguntolu, Simon Alwyn, Arun Natarajan, Jean HesterPituitary
P282 Cortisol but not growth hormone responses are dependent on symptoms during the glucagon stimulation test. Yee Seun Cheah, Kristy Lau, Jackie Gilbert, Alan McGregor, Simon AylwinPituitary
P283 Presentation, management and outcomes in acute pituitary apoplexy: A single centre experience from the United Kingdom William Bleaney, Ian MacFarlane, Nicola Rothwell, Carmel Noonan, Mohsen Javadpour, Christina DaousiPituitary
P284 Validity of the new pituitary apoplexy guideline group scoring system (PAGGS) in the management of pituitary apoplexy: a large retrospective review of 46 patients with classical pituitary apoplexy. Senthil Rajasekaran, Narendra Reddy, Thang Han, Mark Vanderpump, Stephanie Baldeweg, John WassPituitary
P285 ELECTROCARDIOGRAPHIC FEATURES IN CUSHING’S DISEASE: ARE THERE SPECIFIC ECG CHANGES ASSOCIATED WITH HYPERCORTISOLAEMIA? Krystallenia Alexandraki, Gregory Kaltsas, Apostolos Vouliotis, Theodoros Papaioannou, Nikolaos Apostolopoulos, Lauren Trisk, Athanasios Zilos, Scott Akker, Shern Chew, William Drake, Aris Anastasakis, Ashley GrossmanPituitary
P287 Patients with pituitary disease are at risk of under-replacement with levothyroxine Olympia Koulouri, Mohammed A Auldin, Ravi Agarwal, Veronica Kieffer, Carole Robertson, James Falconer Smith, Miles J Levy, Trevor A HowlettPituitary
P288 Anti-allergic cromolyn drugs facilitate annexin 1 secretion from pituitary folliculo-stellate cells David Thomson, John Morris, Helen ChristianPituitary
P289 A fall in serum prolactin level after a 2 hour rest predicts a normal MRI in patients using dopamine antagonist treatment Martin Whyte, Matthew Allum, Sesha Pramodh, Simon AylwinPituitary
P290 Adult Growth Hormone Replacement and Risk of Tumour Recurrence – 15 Year Experience from a Large Single Centre Scott Mackenzie, Georg BrabantPituitary
P291 Fish and Chicks: C-type natriuretic peptide and the development of the pituitary gland in Gallus gallus and Danio rerio. Annisa Chand, Sophia Akbareian, Alex McSloy, Derek Renshaw, Imelda McGonnell, Robert FowkesPituitary
P292 Circadian and pulsatile secretion of copeptin, an arginine vasopressin (AVP) marker, argues against a physiological role of AVP in cortisol release Ken Darzy, Kashinath Dixit, Stephen Shalet, Nils Morgenthaler, Georg BrabantPituitary
P293 Long-term unsynchronised transcriptional cycles in individual living pituitary cells Claire Harper, Barbel Finkenstadt, Dan Woodcock, Sonke Friedrichsen, Sabrina Semprini, Dave Spiller, John Mullins, David Rand, Julian Davis, Mike WhitePituitary
P294 Can we ever stop imaging in surgically treated and radiotherapy naive patients with non-functioning pituitary adenoma? Raghava Reddy Gubbihal, Niki Karavitaki, Nassim Parvizi, Vicky Sangha, Mikiko Watanabe, Simon Cudlip, John AH WassPituitary
P295 Effects on insulin action of dehydroepiandrosterone sulphate replacement in hypopituitary females Claire McHenry, Patrick Bell, Steven Hunter, Christopher Thompson, Hamish Courtney, Cieran Ennis, Brian Sheridan, David McCance, Karen Mullan, Brew AtkinsonPituitary
P296 Cabergoline suppression test - Assessment tool for management of hyperprolactinemia Corin Badiu, Luigi Silvestro, Simona Verzea, Andra CaragheorgheopolPituitary
P297 Should we take macroprolactinoma patients off dopamine agonists at 3 or 5 years as they almost invariably recur? Rebecca Scott, Thomas Barber, Julia Kenkre, Catherine Garnet, John WassPituitary
P298 Onset of Prolactin Gene Transcription in Nascent Pituitary Lactotroph Cells Karen Featherstone, Claire Harper, Anne McNamara, Sabrina Semprini, David Spiller, Alan McNeilly, John Mullins, Michael White, Julian DavisPituitary
P299 Immuno-modulatory Role of Prolactin in Immune Tissues Driven by the Alternative Promoter Anne McNamara, Raheela Awais, Sabrina Semprini, Claire Harper, Karen Featherstone, Dave Spiller, Julian Davis, John Mullins, Mike WhitePituitary
P300 Genetic screening for variability in regulatory regions of SOX2 and implications for hypothalamo-pituitary development. Kyriaki S Alatzoglou, Daniel Kelberman, Charles Buchanan, Mehul T. DattaniPituitary
P302 The effect of the familial pituitary adenoma gene AIP on apoptosis Asil Tahir, Márta Korbonits, Ashley B Grossman, Harvinder S Chahal, Susana Igreja, Chrysanthia A LeontiouPituitary
P303 ONCOGENE-INDUCED SENESCENCE OCCURS IN HUMAN PITUITARY ADENOMAS Munayem Khan, Harvinder Chahal, Suzzane Jordan, Marta Korbonits, Ashley GrossmanPituitary
P304 Pituitary tumours of mice deleted for a multiple endocrine neoplasia type 1 allele have alterations in apoptotic pathway components. Gerard Walls, Paul Newey, Jeshmi Jeyabalan, A Michael Nesbit, Herbert Schulz, Norbert Huebner, Rajesh ThakkerPituitary
P305 MicroRNAs, miR-15a and miR-16-1, are implicated in pituitary tumourigenesis via regulation of cyclin D1. Paul Newey, Rebecca Dyar, Andrew Nesbit, Mahsa Javid, Gerard Walls, Anita Reed, Michael Bowl, Rajesh ThakkerPituitary
P306 Direct control of ovarian functions by ghrelin Alexander SirotkinReproduction
P308 In vivo validation of potential natural products’ abortifacient property mediated through modulation of uterine protein and Vascular Endothelial Growth Factor-C expression in foetal-maternal interface in albino rats Moushumi Das, Anju Jaishi, Hirendra N SarmaReproduction
P309 Alteration of uterine receptivity and modulation of uterine protein expression during periimplantation by natural product from Piper species leads to pregnancy disruption in albino rats Anju Jaishi, Moushumi Das, Hirendra N SarmaReproduction
P310 Factors That Influence The Decision To Perform A Karyotype In Suspected Disorders Of Sex Development: Lessons From The Scottish Genital Anomaly Network Register. Martina Rodie, Ruth McGowan, Amalia Mayo, Paula Midgley, Christopher Driver, Maureen Kinney, David Young, S. Faisal AhmedReproduction
P311 A Possible Cardioprotective Role for Metformin in PCOS: A Study of Clot Structure and Fibrinolysis Ramzi A Ajjan, Reena Aggarwal, Peter J Grant, Eric S Kilpatrick, Thozhukat Sathyapalan, Anne-Marie Coady, Stephen L AtkinReproduction
P312 Clinical Experience of Nebido: Monitoring the efficacy and safety of testosterone undecanoate in men over 60 years of age Diana Mantripp, Rachel Smith, Niki Karavitaki, John WassReproduction
P313 A simple modification of a commercial radioimmunoassay to enable the more accurate measurement of serum testosterone in women Joseph Montalto, Alan McNeil, Chen-Fee Lim, Que Lam, David MitchellReproduction
P314 GLUT4 expression and translocation in immortalised mouse granulosa cells Jalini Joharatnam, Angelos Skodras, Kate Hardy, Stephen FranksReproduction
P315 The role of Thyroid Hormone Transporters MCT8 and MCT10 in the EVT-like cell line HTR8-SVneo Juhela Choudhury, Laurence Loubiere, Elisavet Vasilopoulou, Christopher McCabe, Jayne Franklyn, Mark Kilby, Shiao ChanReproduction
P316 The tyrosine phosphatase, SHP-1, acts on multiple tyrosine kinase receptors to negatively regulate human cytotrophoblast proliferation Karen Forbes, Laura Skinner, John Aplin, Melissa WestwoodReproduction
P317 Localisation of adiponectin receptors in normal and polycystic ovaries Fabio Comim, Sharron Stubbs, Kate Hardy, Stephen FranksReproduction
P318 Expression of Adhesion Molecules in Preantral Mouse Follicles Jocelyn Mora, Mark Fenwick, Stephen Franks, Kate HardyReproduction
P319 Establishment of an in vitro model to study oocyte regulation of gene expression in granulosa cells of preantral follicles Mark Fenwick, Jocelyn Mora, Stephen Franks, Kate HardyReproduction
P320 Activation of testicular melanocortin 3 receptors (MC3-R) inhibits LH-stimulated testosterone production Kemi AKINDELE, Monika HORANIN, Stephen GETTING, Caroline SMITH, Joanne MurrayReproduction
P321 Study of serum visfatin in Egyptian women with polycystic ovary syndrome Rania Sayed Abd ElBaki, Tahany Abd EL MoneimReproduction
P324 Apparent under-reporting of polycystic ovary syndrome in primary care Hamidreza Mani, Miles Levy, Trever Howlett, Laura Gray, David Webb, Bala Srinivasan, Kamlesh Khunti, Melanie DaviesReproduction
P325 Pregnancy adversely affects ability to recall previously seen spatial locations Diane Farrar, Derek Tuffnell, Jo Neill, Kay MarshallReproduction
P326 Female mice expressing constitutively active FSH receptor present with a phenotype of premature follicle depletion, premature aging and teratomas. Hellevi Peltoketo, Leena Strauss, Riikka Karjalainen, Meilin Zhang, Gordon Stamp, Deborah Segaloff, Matti Poutanen, Ilpo HuhtaniemiReproduction
P327 Sexual dimorphism in experimental endotoxaemia. Ellen L Hughes, Julia C Buckingham, Felicity NE GavinsReproduction
P328 Twice-weekly administration of kisspeptin leads to long-term stimulation of reproductive hormone release in infertile women with hypothalamic amenorrhoea Channa N Jayasena, Gurjinder MK Nijher, Ali Abbara, Kevin G Murphy, Adrian Lim, Daksha Patel, Amrish Mehta, Catriona Todd, Radha Ramachandran, Mandy Donaldson, Geoffrey Trew, Mohammad A Ghatei, Stephen R Bloom, Waljit S DhilloReproduction
P329 Metyrapone interference in serum cortisol immunoassay. David Halsall, Laura Owen, Adam Viljoen, Kevin Taylor, Helen Simpson, Krishna Chatterjee, Mark GurnellSteroids
P330 Cyclical epilepsy associated with testosterone replacement Acharya Jayashekara, Daniel FlanaganSteroids
P332 Steroid analysis in patients receiving metyrapone therapy Laura Owen, David Halsall, Alexandra Yates, Brian KeevilSteroids
P333 Reference range data on androsterone glucuronide in healthy male and female volunteers and clinical uses of the assay. Joanne Adaway, Adrian Miller, FCW Wu, Brian KeevilSteroids
P334 A rare cause of massive bilateral adrenal enlargement complicating management of Congenital Adrenal Hyperplasia Sath Nag, Atif Munir, Arif Ullah, Anjali SanthakumarSteroids
P335 DIAGNOSTICALLY DIFFICULT CUSHING’S SYNDROME IN A PHARMACY STUDENT Haris Marath, Ketan DhatariyaSteroids
P336 POST-TRAUMATIC HYPOADRENALISM CASE REPORT Sarika Deshpande, Nishan Wijenaike, John ClarkSteroids
P337 Determination of tandem mass spectrometry specific reference ranges for testosterone, androstenedione and DHEAS Philip Macdonald, Frederick Wu, Laura Owen, Brian KeevilSteroids
P338 A sensitive and specific tandem mass spectrometry assay for the measurement of salivary testosterone Philip Macdonald, Laura Owen, Brian KeevilSteroids
P339 Analysis of cortisol by stable isotope dilution liquid chromatography tandem mass spectrometry (LC-MS/MS) – benefits and pitfalls of rapid analysis of clinical samples Natalie Homer, Scott Denham, Roland Stimson, David Watson, Brian Walker, Ruth AndrewSteroids
P340 Steroid therapy: an unusual alternative to oral replacement via 24 hour subcutaneous infusion device. Sue Stewart, Parth Narendon, Barbara Hudson, Peter Hindmarsh, Nils Krone, Wiebke ArltSteroids
P341 Moderate liquorice consumption enhances salivary DHEA and testosterone levels in healthy volunteers Emad A S Al-Dujaili, Claire Macdonald, Chris KenyonSteroids
P342 Is a raised DHEAS significant when analysed as part of an androgen profile Carrie Chadwick, Brian KeevilSteroids
P343 Application of a highly specific and sensitive ELISA for the estimation of cortisone in biological fluids Hussam Baghdadi, Emad Al-Dujaili, Suzana Almoosawi, Forbes Howie, Ian MasonSteroids
P344 Successful fecundity with addition of night-time dexamethasone to hydrocortisone in a patient with congenital adrenal hyperplasia (CAH) and testicular adrenal rest tumours (TART) Haliza Haniff, Stephen GilbeySteroids
P345 Dexamethasone testing and visceral:subcutaneous fat ratios in patients with adrenal incidentalomas Miguel Debono, Tim Hughes, Charlotte Durrington, Scott Williams, John Newell-PriceSteroids
P346 Salivary aldosterone is a useful marker of serum aldosterone in normotensive individuals Emily McMurray, Brew Atkinson, Karen Mullan, Jennifer Cundick, Brian Sheridan, Patrick BellSteroids
P347 Regulation of Glucocorticoid Receptor Activity by Cellular Stress Laura Davies, Malihah Sadeq, Constantinos Demonacos, Marija Krstic-DemonacosSteroids
P348 -344 C/T polymorphism of aldosterone synthase gene (CYP11B2) and cortisol synthesis in heart failure patients Ioannis Tsorlalis, Robert Fraser, Colette Jackson, Mary Ingram, Christine Holloway, John McMurray, John ConnellSteroids
P349 Urinary steroid metabolite profiling in 11β-HSD1 and H6PDH transgenic mice Nina Semjonous, Beverly Hughes, Elizabeth Walker, Gareth Lavery, Paul StewartSteroids
P350 Epitopes of Pterin-Dependent Hydroxylases in Autoimmune Polyendocrine Syndrome Type 1 Ng'weina Francis Magitta, Eirik Bratland, Anette S.B Wolff, Jan Haavik, Per Motern Knappskog, Eystein Sverre HusebyeSteroids
P351 Responses of putative adrenocortical stem/progenitor cells and transiently amplifying cells to ACTH Hamish Morrison, Frida Nilsson, Su-Ping Chang, John West, Christopher Kenyon, Steven MorleySteroids
P352 Assessing adrenal status in patients before and after coronary artery bypass graft surgery Miguel Debono, Lorcan Sheppard, Sarah Irving, Zoe Brookes, John Newell-Price, John Ross, Richard RossSteroids
P353 Ongoing symptoms in treated Addison’s disease significantly impair health-related quality of life Katherine White, Alick MackaySteroids
P354 Low testosterone and Androgen Receptor Insensitivity Results in Decreased AMP-Activated Protein Kinase Activity (AMPK) in the Liver in the Testicular Feminised (Tfm) Mouse Susana Igreja, Joanne E. Nettleship, Richard D. Jones, Kevin S. Channer, T. Hugh Jones, Márta KorbonitsSteroids
P355 Salivary annexin 1 has a diurnal rhythm but does not share an awakening response with cortisol at 30 minutes Derek Renshaw, Marta Korbonits, Rod Flower, Mauro Perretti, Robert FowkesSteroids
P356 Use of Bioluminescence Resonance Energy Transfer to reveal the structural dynamics of the ACTH receptor complex Sadani Cooray, Adrian ClarkSteroids
P357 6-Phosphogluconate dehydrogenase – an NADPH-generating enzyme in the lumen of the endoplasmic reticulum Iwona Bujalska, Jonathan Ride, Paul Stewart, Elizabeth WalkerSteroids
P358 Hepatic vein cannulation and stable isotope tracer infusion reveals that liver cortisol regeneration by 11β-HSD1 is sustained in obese men with type 2 diabetes mellitus, providing a target for enzyme inhibition Roland Stimson, Ruth Andrew, Norma McAvoy, Dhiraj Tripathi, Peter Hayes, Brian WalkerSteroids
P359 Variation in the aldosterone synthase gene may alter gene transcription via altered transcription factor binding. Frances McManus, William Sands, Eleanor Davies, John ConnellSteroids
P360 Replicated association of regions at CYP11B1/B2 locus with hypertension in Caucasians Samantha Alvarez-Madrazo, Sandosh Padmanabhan, Elaine Friel, Scott MacKenzie, Morris Brown, Mark Caulfield, Patricia Munroe, Martin Farrall, John Webster, Nilesh Samani, Anna Dominiczak, Olle Melander, Eleanor Davies, John ConnellSteroids
P361 Anti-inflammatory effects of SGRMs: are they dependent on DUSP1? Eugenie Joanny, Joana Martins, Andrew ClarkSteroids
P362 MicroRNA expression profiling of non-tumorous adrenal tissue and modulation of 11β-hydroxylase (CYP11B1) & aldosterone synthase (CYP11B2) genes by miR-24. Stacy Wood, Scott MacKenzie, Paul Stewart, Robert Fraser, John Connell, Eleanor DaviesSteroids
P363 Is increased 11β-HSD1 expression a key factor underpinning intrinsic and extrinsic skin aging? Ana Tiganescu, Andrew Mayes, Rowan Hardy, Paul Stewart, Elizabeth WalkerSteroids
P364 Functional characterisation of 21-hydroxylase gene mutations is a valuable tool for genetic counselling – in vitro and in silico analysis of six novel CYP21A2 sequence variants. Silvia Parajes, Lourdes Loidi, Vivek Dhir, Marcos Morey, Fernando Dominguez, Wiebke Arlt, Nils KroneSteroids
P365 Chronic glucocorticoid treatment causes de-novo methylation of Tpit and causes continued reduction in POMC expression after glucocorticoid withdrawal Alia Munir, Rachel Powell, Adim Eltobgi, John Newell-PriceSteroids
P366 SPECTRUM OF THYROID DISORDERS IN OBAFEMI AWOLOWO UNIVERSITY TEACHING HOSPITAL COMPLEX, ILE-IFE. ROSEMARY IKEM, JOSEPH ADEBAYO, DAVID SOYOYE, BUSOLA OJO, EJIOFOR UGWU, BABATOPE KOLAWOLEThyroid
P368 A case of Severe Hypothyroidism treated with supervised weekly thyroxine. Shankar Dhandabani, Muthuram Rajaram, Haroon SiddiqueThyroid
P369 A difficult case of very aggressive Thyroid eye disease Saravanan Balaguruswamy, WMHS Chandrasekara, S McNultyThyroid
P370 A case of non-Graves thyroid eye disease Leila Faghahati, Ritwik BanerjeeThyroid
P372 Technetium Pertechnetate Scanning In The Differential Diagnosis of Benign Thyroid Disease Caryn Wujanto, Edward Wallitt, Khalid AhmedThyroid
P373 AUDIT ON FINE NEEDLE ASPIRATION OF THYROID Kumar Thulasidass, Penny HyattThyroid
P374 THE MANY FACES OF HYPERTHYROIDISM IN PRIMARY CARE Anh Tran, Vidhu Nayyar, Steve Hyer, Andrew RodinThyroid
P375 A Case of Spousal Abuse Secondary to Thyrotoxicosis Darshna Patel, Jackie GilbertThyroid
P376 A 10-year retrospective analysis of variable-dose radioactive iodine therapy for hyperthyroidism R Abdul Wahab, MJ Cullen, JJ Nolan, ML Healy, SE McQuaid, G O'ReillyThyroid
P377 An unusual presentation of hyperthyroidism Simon Holmes, VKB PrabhakarThyroid
P381 Do we warn patients about the risk of neutropenia associated with the use of anti-thyroid drugs? Muhammad Butt, Itopa Abedo, Fong Chau, Andrew JohnsonThyroid
P382 Severe thyrotoxicosis due to metastatic differentiated thyroid carcinoma Thomas Dacruz, Christine Kotonya, Roger Morgan, M Keston JonesThyroid
P383 Pancytopenia and Nephrotic syndrome related to autoimmune hypothyroidism: a case report MANJUSHA RATHI, STEVE PEACEYThyroid
P384 Radioactive-Iodine therapy: A patient satisfaction survey Sarah Ali, Linda Pontello, Sanjeev Mehta, Daniel Darko, Stuart McHardy-YoungThyroid
P385 Atypical Presentation of Riedel`s Thyroiditis: Multifocal Nodular Fibrosis & Resolution with Levothyroxine Sampath Satish Kumar, Fraser Sheila, Andrew Scarsbrook, Ken Maclennan, Mark Lansdown, Robert MurrayThyroid
P386 Interpreting adrenal status in thyrotoxicosis Louise Breen, Barbara McGowan, Paul Carroll, Stephen ThomasThyroid
P387 Bulbar myopathy as a rare presenting feature of severe thyrotoxicosis in an elderly man Allison Martin, Kenneth Foster, Sunil ZachariahThyroid
P388 Radioactive Iodine (RAI) therapy for benign thyroid disease – Joint RAI clinic Hassan Kahal, Alpa Modi, Divya Santosh, Kamal El Rashid, Saima Almas, Mohamed MalikThyroid
P389 TSH Receptor Antibody assay: its use in a tertiary centre. Aikaterini Theodoraki, Gareth L. Jones, Sithara Perera, Darshna Patel, Jennifer C. Parker, Chris C. Bunn, Mike Thomas, Pierre-Mark Bouloux, Mark VanderpumpThyroid
P390 Thyrotoxicosis presenting as intussusception Hala Alsafadi, David Dutton, Sailesh SankerThyroid
P391 Practical value of 131I Whole Body Scan in follow up of patients with differentiated thyroid cancer. Agnieszka Pazderska, Michael Cullen, Geraldine O'Reilly, Vivion Crowley, Marie Louise HealyThyroid
P392 An audit of the management of all patients with thyroid cancer treated with 131 I for remnant ablation or persistent disease at a tertiary referral hospital between 2003 and 2008. Agnieszka Pazderska, Michael Cullen, Geraldine O'Reilly, Marie Louise HealyThyroid
P393 Radioiodine for Graves’ Disease: what do patients really think? Rebecca Fletcher, Kenneth Muir, John Bevan, Prakash AbrahamThyroid
P394 Treated Grave's Disease? think again! Aswathiah Srinath, Ben Whitelaw, Sharaf IbrahimThyroid
P395 An evidence based protocol for the early identification and management of hypocalcaemia following total thyroidectomy Neil Sharma, David Howe, Neil Gittoes, John WatkinsonThyroid
P396 A case of thyroid hormone resistance in a family with 3 generations of thyroid disease Doros Polydorou, Daniel Kannapan, Sami Kenz, Angela Paisley, Tara KearneyThyroid
P397 The Use of District-Wide Laboratory Database to Identify New Patients with Persistent Hyperthyroidism Yasmeen Khalid, B M Singh, Varadarajan Baskar, Harit N BuchThyroid
P398 Dilated cardiomyopathy and atrial fibrillation secondary to Resistance to Thyroid Hormone Arif Ullah, Atif Munir, Sath NagThyroid
P399 Iopanoic Acid – a Bridge to Surgery When All Else Fails in Complicated Hyperthyroidism Victoria Parker, Alistair Green, Piyush Jani, David Halsall, Krishna Chatterjee, Helen SimpsonThyroid
P400 Selective malabsorption of thyroid hormone or selective intake? Rajeev Raghavan, Wolf Woltersdorf, Colin DayanThyroid
P401 Management and follow up of post operative hypocalcemia after thyroidectomy- a pilot study Anjali Santhakumar, Atif Munir, Pat Durning, Sath NagThyroid
P402 Clinical Management and Outcomes of Anti-TSH Receptor Antibody Positive Pregnancies AJ Stears, R Stewart, DJ Halsall, AL Ogilvy-Stuart, CJ Patient, HL Simpson, A Swamy, VK ChatterjeeThyroid
P403 123I uptake scanning after radioiodine treatment for thyrotoxicosis prevents delayed diagnosis of radioiodine induced hypothyroidism Eleanor Murray, Doreen Foulis, E Marie FreelThyroid
P404 Sunitinib induced hypothyroidism - a retrospective analysis Koteshwara Muralidhara, Debra Joseph, Rustom Guzder, Sarah Rudman, Barbara McGowan, Simon Chowdhury, Paul Carroll, Jake PowrieThyroid
P405 Screening and Management of thyroid dysfunction in pregnancy Srikanth Mada, Safira Tazeen, Ferrari Kwan, Ravi Erakulapati, Mary Bilous, Rudy BilousThyroid
P406 Diagnostic and financial benefits of checking TSH receptor antibodies in patients with thyrotoxicosis Violet Fazal-Sanderson, Theingi Aung, John AH Wass, Niki KaravitakiThyroid
P407 Should the cytological finding of Thy3 mandate surgical excision? Indrani Chakraborti, Simon Aylwin, Alan McGregor, Klaus Martin Schulte, Salvador Diaz-Cano, Jackie GilbertThyroid
P408 Characteristics of patients requiring more than one dose of radioactive iodine to induce cure of hyperthyroidism Barbara Torlinska, Jayne Franklyn, Kristien BoelaertThyroid
P409 Screening of six novel candidate genes for association with Graves’ disease Ruth Tisdall, Matthew Simmonds, Paul Newby, Jayne Franklyn, Stephen Gough, Oliver BrandThyroid
P410 The Physiological Role of Thyroid Hormone in the Hypothalamic Ventromedial Nucleus John R Counsell, Errol Richardson, James V GardinerThyroid