06 Mar 2012
Heat treatment resulted in decreased blood glucose and non-esterified fatty acids; increased leptin, adiponectin and insulin secretion; and greater glucose disposal. Leptin, adiponectin, leptin and adiponectin receptors, insulin receptor substrate-1 and glucose transporter mRNAs were up-regulated in HS mice. This study provides evidence that HS improves leptin and adiponectin signalling in adipose tissue, muscle and liver. Heat stress was responsible for improving insulin sensitivity and glucose uptake in peripheral tissues, probably mediated by adipokines Collectively, these data indicate that moderate chronic heat treatment could be a potential therapeutic treatment for disorders associated with insulin resistance. Morera et al. (2012) Journal of Molecular Endocrinology 48 129-138.
Read the full article at: DOI: 10.1530/JME-11-0054.