Cistromics of hormone-dependent cancer
Mathieu Lupien and Myles Brown review the wealth of
information derived from cistrome-based studies and
describe how this reveals the core concepts of
transcriptional regulation. Since this has a direct impact
on signaling through nuclear receptors, these discoveries
should significantly influence the development of novel
therapeutic strategies directed against multiple types of
cancer. Lupien, M and Brown, M. Endocrine-Related Cancer 16 (2) 381 -389, DOI: 10.1677/ERC-09-0038