Society for Endocrinology - a world-leading authority on hormones
Grants and Awards
SfE BES Conference
SfE BES 2019
11 November 2019
12 November 2019
13 November 2019
Session starts at 15:05
5β-reductase (AKR1D1) is downregulated in patients with non-alcoholic fatty liver disease and protects against hepatocellular carcinoma cell proliferation in vitro.
(University of Oxford, United Kingdom)
5β-reductase (AKR1D1) isoforms differentially regulate natural and synthetic glucocorticoid clearance and glucocorticoid receptor activation in vitro.
Nathan Appanna, Anastasia Arvaniti, Elena Gangitano, Karen Morris, Sherly George, Brian Keevil, Jeremy Tomlinson, Nikolaos Nikolaou
AKR1D1 (5β-reductase) deletion drives hepatic inflammation, fibrosis and tumour development in vivo.
Shelley Harris, Nikolaos Nikolaou, Anastasia Arvaniti, Roger Cox, Laura Gathercole, Jeremy Tomlinson