Members should be aware that Pharmanovia has confirmed the permanent discontinuation of macimorelin due to manufacturing issues. We understand that there is currently no remaining supply available in the UK. If you have any remaining stock of macimorelin, please check the expiry date carefully, as the final batch produced by Pharmanovia had an expiry date of 30 June 2026.

Clinicians who use macimorelin for the diagnosis of adult growth hormone deficiency should consider established alternative diagnostic tests, including the insulin tolerance test (ITT) and glucagon stimulation test (GST), in line with local protocols and clinical judgement.