Ronchi and colleagues evaluate the efficacy of gamma knife radiosurgery in a large series of acromegalic patients over a 10 year monitoring period. High cure rates and adequate control with low side effects – such as visual impairment or recurrence – was tempered with an increase in novel pituitary deficiencies in 50% of the patient group such as hypoadrenalism. Ronchi et al., Clinical Endocrinology, DOI:10.1111/j.1365-2265.2009.03589.x